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Biology of Tissue Inhibitor of Metalloproteinase 3 (TIMP3), and Its Therapeutic Implications in Cardiovascular Pathology

Frontiers in physiology, 2020-06, Vol.11, p.661-661

2020

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Extracellular matrix, regional heterogeneity of the aorta, and aortic aneurysm

Experimental and Molecular Medicine, 2019, 51(0), , pp.1-15

2019

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Cardiac fibroblasts, fibrosis and extracellular matrix remodeling in heart disease

Fibrogenesis & tissue repair, 2012-09, Vol.5 (1), p.15-15, Article 15

2012

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Guidelines for measuring cardiac physiology in mice

American journal of physiology. Heart and circulatory physiology, 2018-04, Vol.314 (4), p.H733-H752

2018

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Cell-Specific Functions of ADAM17 Regulate the Progression of Thoracic Aortic Aneurysm

Circulation research, 2018-07, Vol.123 (3), p.372-388

2018

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Angiotensin II induced proteolytic cleavage of myocardial ACE2 is mediated by TACE/ADAM-17: A positive feedback mechanism in the RAS

Journal of molecular and cellular cardiology, 2014-01, Vol.66, p.167-176

2014

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Angiotensin-Converting Enzyme 2 Suppresses Pathological Hypertrophy, Myocardial Fibrosis, and Cardiac Dysfunction

Circulation (New York, N.Y.), 2010-08, Vol.122 (7), p.717-728

2010

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Divergent roles of matrix metalloproteinase 2 in pathogenesis of thoracic aortic aneurysm

Arteriosclerosis, thrombosis, and vascular biology, 2015-04, Vol.35 (4), p.888

2015

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Myocardial overexpression of TIMP3 after myocardial infarction exerts beneficial effects by promoting angiogenesis and suppressing early proteolysis

American journal of physiology. Heart and circulatory physiology, 2017-08, Vol.313 (2), p.H224-H236

2017

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Modulation of Cardiac Fibrosis in and Beyond Cells

Frontiers in molecular biosciences, 2021-10, Vol.8, p.750626-750626

2021

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Tissue inhibitor of metalloproteinases (TIMPs) in heart failure

Heart failure reviews, 2012-09, Vol.17 (4-5), p.693-706

2012

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Prevention of Angiotensin II–Mediated Renal Oxidative Stress, Inflammation, and Fibrosis by Angiotensin-Converting Enzyme 2

Hypertension (Dallas, Tex. 1979), 2011-02, Vol.57 (2), p.314-322

2011

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Guidelines for in vivo mouse models of myocardial infarction

American journal of physiology. Heart and circulatory physiology, 2021-12, Vol.321 (6), p.H1056-H1073

2021

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Cardiomyocyte-specific disruption of soluble epoxide hydrolase limits inflammation to preserve cardiac function

American journal of physiology. Heart and circulatory physiology, 2022-10, Vol.323 (4), p.H670-H687

2022

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The Non-Fibrillar Side of Fibrosis: Contribution of the Basement Membrane, Proteoglycans, and Glycoproteins to Myocardial Fibrosis

Journal of cardiovascular development and disease, 2019-09, Vol.6 (4), p.35

2019

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PI3Kα-regulated gelsolin activity is a critical determinant of cardiac cytoskeletal remodeling and heart disease

Nature communications, 2018-12, Vol.9 (1), p.5390-14, Article 5390

2018

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Iron-overload injury and cardiomyopathy in acquired and genetic models is attenuated by resveratrol therapy

Scientific reports, 2015-12, Vol.5 (1), p.18132-18132, Article 18132

2015

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Fenofibrate, but not ezetimibe, prevents fatty liver disease in mice lacking phosphatidylethanolamine N-methyltransferase

Journal of lipid research, 2017-04, Vol.58 (4), p.656-667

2017

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Circulating levels of tumor necrosis factor-alpha receptor 2 are increased in heart failure with preserved ejection fraction relative to heart failure with reduced ejection fraction: evidence for a divergence in pathophysiology

PloS one, 2014-06, Vol.9 (6), p.e99495-e99495

2014

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Human Recombinant ACE2 Reduces the Progression of Diabetic Nephropathy

Diabetes (New York, N.Y.), 2010-02, Vol.59 (2), p.529-538

2010

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Vitamin E alleviates non-alcoholic fatty liver disease in phosphatidylethanolamine N-methyltransferase deficient mice

Biochimica et biophysica acta. Molecular basis of disease, 2019-01, Vol.1865 (1), p.14-25

2019

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Antenatal Sildenafil Treatment Attenuates Pulmonary Hypertension in Experimental Congenital Diaphragmatic Hernia

Circulation (New York, N.Y.), 2011-05, Vol.123 (19), p.2120-2131

2011

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Cardioprotective Effects Mediated by Angiotensin II Type 1 Receptor Blockade and Enhancing Angiotensin 1-7 in Experimental Heart Failure in Angiotensin-Converting Enzyme 2–Null Mice

Hypertension (Dallas, Tex. 1979), 2012-06, Vol.59 (6), p.1195-1203

2012

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TIMP2 Deficiency Accelerates Adverse Post–Myocardial Infarction Remodeling Because of Enhanced MT1-MMP Activity Despite Lack of MMP2 Activation

Circulation research, 2010-03, Vol.106 (4), p.796-808

2010

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MMP-2 Mediates Angiotensin II–Induced Hypertension Under the Transcriptional Control of MMP-7 and TACE

Hypertension (Dallas, Tex. 1979), 2011-01, Vol.57 (1), p.123-130

2011

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Biology of Tissue Inhibitor of Metalloproteinase 3 (TIMP3), and Its Therapeutic Implications in Cardiovascular Pathology

Extracellular matrix, regional heterogeneity of the aorta, and aortic aneurysm

Cardiac fibroblasts, fibrosis and extracellular matrix remodeling in heart disease

Guidelines for measuring cardiac physiology in mice

Cell-Specific Functions of ADAM17 Regulate the Progression of Thoracic Aortic Aneurysm

Angiotensin II induced proteolytic cleavage of myocardial ACE2 is mediated by TACE/ADAM-17: A positive feedback mechanism in the RAS

Angiotensin-Converting Enzyme 2 Suppresses Pathological Hypertrophy, Myocardial Fibrosis, and Cardiac Dysfunction

Divergent roles of matrix metalloproteinase 2 in pathogenesis of thoracic aortic aneurysm

Myocardial overexpression of TIMP3 after myocardial infarction exerts beneficial effects by promoting angiogenesis and suppressing early proteolysis

Modulation of Cardiac Fibrosis in and Beyond Cells

Tissue inhibitor of metalloproteinases (TIMPs) in heart failure

Prevention of Angiotensin II–Mediated Renal Oxidative Stress, Inflammation, and Fibrosis by Angiotensin-Converting Enzyme 2

Guidelines for in vivo mouse models of myocardial infarction

Cardiomyocyte-specific disruption of soluble epoxide hydrolase limits inflammation to preserve cardiac function

The Non-Fibrillar Side of Fibrosis: Contribution of the Basement Membrane, Proteoglycans, and Glycoproteins to Myocardial Fibrosis

PI3Kα-regulated gelsolin activity is a critical determinant of cardiac cytoskeletal remodeling and heart disease

Iron-overload injury and cardiomyopathy in acquired and genetic models is attenuated by resveratrol therapy

Fenofibrate, but not ezetimibe, prevents fatty liver disease in mice lacking phosphatidylethanolamine N-methyltransferase

Circulating levels of tumor necrosis factor-alpha receptor 2 are increased in heart failure with preserved ejection fraction relative to heart failure with reduced ejection fraction: evidence for a divergence in pathophysiology

Human Recombinant ACE2 Reduces the Progression of Diabetic Nephropathy

Vitamin E alleviates non-alcoholic fatty liver disease in phosphatidylethanolamine N-methyltransferase deficient mice

Antenatal Sildenafil Treatment Attenuates Pulmonary Hypertension in Experimental Congenital Diaphragmatic Hernia

Cardioprotective Effects Mediated by Angiotensin II Type 1 Receptor Blockade and Enhancing Angiotensin 1-7 in Experimental Heart Failure in Angiotensin-Converting Enzyme 2–Null Mice

TIMP2 Deficiency Accelerates Adverse Post–Myocardial Infarction Remodeling Because of Enhanced MT1-MMP Activity Despite Lack of MMP2 Activation

MMP-2 Mediates Angiotensin II–Induced Hypertension Under the Transcriptional Control of MMP-7 and TACE

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