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Evaluating the rate of reversal of fentanyl-induced respiratory depression using a novel long-acting naloxone nanoparticle, cNLX-NP

Frontiers in psychiatry, 2024-03, Vol.15, p.1366186-1366186

2024

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Slow‐sustained delivery of naloxone reduces typical naloxone‐induced precipitated opioid withdrawal effects in male morphine‐dependent mice

Journal of neuroscience research, 2022-01, Vol.100 (1), p.339-352

2022

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SuFEx-based strategies for the preparation of functional particles and cation exchange resins

Chemical communications (Cambridge, England), 2019-04, Vol.55 (27), p.3891-3894

2019

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A de Novo Enantioselective Total Synthesis of (−)-Laulimalide

Journal of the American Chemical Society, 2002-11, Vol.124 (46), p.13654-13655

2002

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Anti-Strychnine Immunoconjugate Reduces the Effects of Strychnine-Induced Toxicity in Mice

ACS chemical neuroscience, 2023-04, Vol.14 (7), p.1291-1298

2023

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Design, synthesis, and biological evaluation of C6-difluoromethylenated epoxymorphinan Mu opioid receptor antagonists

RSC medicinal chemistry, 2022-02, Vol.13 (2), p.175-182

2022

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Hit-to-Lead Optimization and Discovery of 5‑((5-([1,1′-Biphenyl]-4-yl)-6-chloro‑1H‑benzo[d]imidazol-2-yl)oxy)-2-methylbenzoic Acid (MK-3903): A Novel Class of Benzimidazole-Based Activators of AMP-Activated Protein Kinase

Journal of medicinal chemistry, 2017-11, Vol.60 (21), p.9040-9052

2017

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Multivalent Vaccination Strategies Protect against Exposure to Polydrug Opioid and Stimulant Mixtures in Mice and Rats

ACS pharmacology & translational science, 2024-02, Vol.7 (2), p.363-374

2024

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Efficacy and Selectivity of Monovalent and Bivalent Vaccination Strategies to Protect against Exposure to Carfentanil, Fentanyl, and Their Mixtures in Rats

ACS pharmacology & translational science, 2022-05, Vol.5 (5), p.331-343

2022

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Design, synthesis, and biological evaluation of C 6 -difluoromethylenated epoxymorphinan Mu opioid receptor antagonists

RSC medicinal chemistry, 2022-02, Vol.13 (2), p.175-182

2022

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Covalently Loaded Naloxone Nanoparticles as a Long-Acting Medical Countermeasure to Opioid Poisoning

ACS pharmacology & translational science, 2021-10, Vol.4 (5), p.1654-1664

2021

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Covalent Poly(lactic acid) Nanoparticles for the Sustained Delivery of Naloxone

ACS applied bio materials, 2019-08, Vol.2 (8), p.3418-3428

2019

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Osteoconductive Enhancement of Polyether Ether Ketone: A Mild Covalent Surface Modification Approach

ACS applied bio materials, 2018-10, Vol.1 (4), p.1047-1055

2018

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One-Pot Phenolic-Initiated Mechanochemical Synthesis of Poly(lactic acid) Nanoparticles: Application of the Artificial Neural Network Algorithm to Perform Sensitivity Assessment Models

Macromolecules, 2022-11, Vol.55 (21), p.9740-9750

2022

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Systems cell biology knowledge created from high content screening

Assay and drug development technologies, 2005-10, Vol.3 (5), p.501-514

2005

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An Investigation of Imidazole and Oxazole Syntheses Using Aryl-Substituted TosMIC Reagents1

Journal of organic chemistry, 2000-03, Vol.65 (5), p.1516-1524

2000

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Design, synthesis, and biological evaluation of C-difluoromethylenated epoxymorphinan Mu opioid receptor antagonists

RSC medicinal chemistry, 2022-02, Vol.13 (2), p.175-182

2022

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A Highly Enantioselective Conjugate Reduction of 3-Arylinden-1-ones Using Bakers' Yeast for the Preparation of (S)-3-Arylindan-1-ones

Organic letters, 1999-12, Vol.1 (11), p.1839-1842

1999

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Unexpected Reactivity of Imidazo[2,1-b]thiazolines with Organometallic Reagents

Organic letters, 2000-09, Vol.2 (18), p.2877-2880

2000

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Hit-to-Lead Optimization and Discovery of 5-((5-([1,1′-Biphenyl]-4-yl)-6-chloro-1 H -benzo[ d ]imidazol-2-yl)oxy)-2-methylbenzoic Acid (MK-3903): A Novel Class of Benzimidazole-Based Activators of AMP-Activated Protein Kinase

Journal of medicinal chemistry, 2017-11, Vol.60 (21), p.9040-9052

2017

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An investigation of imidazole and oxazole syntheses using aryl-substituted TosMIC reagents

Journal of organic chemistry, 2000-03, Vol.65 (5), p.1516-1524

2000

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An Investigation of Imidazole and Oxazole Syntheses Using Aryl-Substituted TosMIC Reagents 1

Journal of organic chemistry, 2000-03, Vol.65 (5), p.1516-1524

2000

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Catalytic, asymmetric acyl halide-aldehyde cyclocondensations in complex molecule synthesis and application to the installation of quaternary carbon stereocenters

Kassick, Andrew J

2004

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Evaluating the rate of reversal of fentanyl-induced respiratory depression using a novel long-acting naloxone nanoparticle, cNLX-NP

Slow‐sustained delivery of naloxone reduces typical naloxone‐induced precipitated opioid withdrawal effects in male morphine‐dependent mice

SuFEx-based strategies for the preparation of functional particles and cation exchange resins

A de Novo Enantioselective Total Synthesis of (−)-Laulimalide

Anti-Strychnine Immunoconjugate Reduces the Effects of Strychnine-Induced Toxicity in Mice

Design, synthesis, and biological evaluation of C6-difluoromethylenated epoxymorphinan Mu opioid receptor antagonists

Hit-to-Lead Optimization and Discovery of 5‑((5-([1,1′-Biphenyl]-4-yl)-6-chloro‑1H‑benzo[d]imidazol-2-yl)oxy)-2-methylbenzoic Acid (MK-3903): A Novel Class of Benzimidazole-Based Activators of AMP-Activated Protein Kinase

Multivalent Vaccination Strategies Protect against Exposure to Polydrug Opioid and Stimulant Mixtures in Mice and Rats

Efficacy and Selectivity of Monovalent and Bivalent Vaccination Strategies to Protect against Exposure to Carfentanil, Fentanyl, and Their Mixtures in Rats

Design, synthesis, and biological evaluation of C 6 -difluoromethylenated epoxymorphinan Mu opioid receptor antagonists

Covalently Loaded Naloxone Nanoparticles as a Long-Acting Medical Countermeasure to Opioid Poisoning

Covalent Poly(lactic acid) Nanoparticles for the Sustained Delivery of Naloxone

Osteoconductive Enhancement of Polyether Ether Ketone: A Mild Covalent Surface Modification Approach

2‑[(3aR,4R,5S,7aS)‑5-{(1S)‑1-[3,5-Bis(trifluoromethyl)phenyl]-2-hydroxyethoxy}-4-(2-methylphenyl)octahydro‑2H‑isoindol-2-yl]-1,3-oxazol-4(5H)‑one: A Potent Human NK1 Receptor Antagonist with Multiple Clearance Pathways

One-Pot Phenolic-Initiated Mechanochemical Synthesis of Poly(lactic acid) Nanoparticles: Application of the Artificial Neural Network Algorithm to Perform Sensitivity Assessment Models

Systems cell biology knowledge created from high content screening

An Investigation of Imidazole and Oxazole Syntheses Using Aryl-Substituted TosMIC Reagents1

Design, synthesis, and biological evaluation of C-difluoromethylenated epoxymorphinan Mu opioid receptor antagonists

A Highly Enantioselective Conjugate Reduction of 3-Arylinden-1-ones Using Bakers' Yeast for the Preparation of (S)-3-Arylindan-1-ones

Unexpected Reactivity of Imidazo[2,1-b]thiazolines with Organometallic Reagents

Hit-to-Lead Optimization and Discovery of 5-((5-([1,1′-Biphenyl]-4-yl)-6-chloro-1 H -benzo[ d ]imidazol-2-yl)oxy)-2-methylbenzoic Acid (MK-3903): A Novel Class of Benzimidazole-Based Activators of AMP-Activated Protein Kinase

An investigation of imidazole and oxazole syntheses using aryl-substituted TosMIC reagents

2-[(3a R ,4 R ,5 S ,7a S )-5-{(1 S )-1-[3,5-Bis(trifluoromethyl)phenyl]-2-hydroxyethoxy}-4-(2-methylphenyl)octahydro-2 H -isoindol-2-yl]-1,3-oxazol-4(5 H )-one: A Potent Human NK 1 Receptor Antagonist with Multiple Clearance Pathways

An Investigation of Imidazole and Oxazole Syntheses Using Aryl-Substituted TosMIC Reagents 1

Catalytic, asymmetric acyl halide-aldehyde cyclocondensations in complex molecule synthesis and application to the installation of quaternary carbon stereocenters

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