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Quinazolinone-Based Anticancer Agents: Synthesis, Antiproliferative SAR, Antitubulin Activity, and Tubulin Co-crystal Structure

Journal of medicinal chemistry, 2018-02, Vol.61 (3), p.1031-1044

2018

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In Vitro Evaluation of the Potential for Drug Interactions by Salidroside

Nutrients, 2023-08, Vol.15 (17), p.3723

2023

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Safety of a Sustainably Produced, Bioengineered, Nature-Identical Salidroside Compound

Nutrients, 2022-06, Vol.14 (11), p.2330

2022

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STX140, but not paclitaxel, inhibits mammary tumour initiation and progression in C3(1)/SV40 T/t-antigen transgenic mice

PloS one, 2013-12, Vol.8 (12), p.e80305

2013

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IRC‐083864, a novel bis quinone inhibitor of CDC25 phosphatases active against human cancer cells

International journal of cancer, 2009-03, Vol.124 (6), p.1449-1456

2009

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Inhibition of human tumor cell growth in vivo by an orally bioavailable inhibitor of CDC25 phosphatases

Molecular cancer therapeutics, 2005-09, Vol.4 (9), p.1378-1387

2005

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3,17-Disubstituted 2-Alkylestra-1,3,5(10)-trien-3-ol Derivatives: Synthesis, In Vitro and In Vivo Anticancer Activity

Journal of medicinal chemistry, 2007-09, Vol.50 (18), p.4431-4443

2007

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Tetrahydroisoquinolinone-Based Steroidomimetic and Chimeric Microtubule Disruptors

ChemMedChem, 2014-01, Vol.9 (1), p.85-108

2014

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Synthesis, Antitubulin, and Antiproliferative SAR of C3/C1-Substituted Tetrahydroisoquinolines

ChemMedChem, 2014-02, Vol.9 (2), p.350-370

2014

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Membrane structure modulation, protein kinase C alpha activation, and anticancer activity of minerval

Molecular pharmacology, 2005-02, Vol.67 (2), p.531-540

2005

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Anticancer Activity of BIM-46174, a New Inhibitor of the Heterotrimeric G alpha /G beta gamma Protein Complex

Cancer research (Chicago, Ill.), 2006-09, Vol.66 (18), p.9227-9234

2006

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2-MeOE2bisMATE and 2-EtE2bisMATE induce cell cycle arrest and apoptosis in breast cancer xenografts as shown by a novel ex vivo technique

Breast cancer research and treatment, 2008-09, Vol.111 (2), p.251-260

2008

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Anticancer activity of BIM-46174, a new inhibitor of the heterotrimeric Gα/Gβγ protein complex

Cancer research (Chicago, Ill.), 2006-09, Vol.66 (18), p.9227-9234

2006

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Homocamptothecins: Synthesis and Antitumor Activity of Novel E-Ring-Modified Camptothecin Analogues

Journal of medicinal chemistry, 1998-12, Vol.41 (27), p.5410-5419

1998

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Cover Picture: Tetrahydroisoquinolinone-Based Steroidomimetic and Chimeric Microtubule Disruptors (ChemMedChem 1/2014)

ChemMedChem, 2014-01, Vol.9 (1), p.1-1

2014

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A novel synthetic inhibitor of CDC25 phosphatases: BN82002

Cancer research (Chicago, Ill.), 2004-05, Vol.64 (9), p.3320-3325

2004

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IRC-083927 is a new tubulin binder that inhibits growth of human tumor cells resistant to standard tubulin-binding agents

Molecular cancer therapeutics, 2008-08, Vol.7 (8), p.2426-2434

2008

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IIn Vitro/I Evaluation of the Potential for Drug Interactions by Salidroside

Nutrients, 2023-08, Vol.15 (17)

2023

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Recombinant Anti-ErbB2 Immunotoxins Containing Pseudomonas Exotoxin

Proceedings of the National Academy of Sciences - PNAS, 1992-07, Vol.89 (13), p.5867-5871

1992

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Therapy of an animal model of human gastric cancer using a combination of anti-erbB-2 monoclonal antibodies

Cancer research (Chicago, Ill.), 1992-05, Vol.52 (10), p.2771-2776

1992

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AR36A36.11.1, a monoclonal antibody targeting CD59, enhances complement activity and exhibits potent in vivo efficacy in multiple human cancer models

Molecular immunology, 2007-09, Vol.44 (16), p.3948-3949

2007

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A Novel Synthetic Inhibitor of CDC25 Phosphatases

Cancer research (Chicago, Ill.), 2004-05, Vol.64 (9), p.3320-3325

2004

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A Mitogenic Peptide Amide Encoded within the E Peptide Domain of the Insulin-Like Growth Factor IB Prohormone

Proceedings of the National Academy of Sciences - PNAS, 1992-09, Vol.89 (17), p.8107-8111

1992

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STX140, but Not Paclitaxel, Inhibits Mammary Tumour Initiation and Progression in C3

PloS one, 2013-12, Vol.8 (12), p.e80305

2013

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The homocamptothecin BN 80915 is a highly potent orally active topoisomerase I poison

Anti-cancer drugs, 2001-01, Vol.12 (1), p.9-19

2001

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Quinazolinone-Based Anticancer Agents: Synthesis, Antiproliferative SAR, Antitubulin Activity, and Tubulin Co-crystal Structure

In Vitro Evaluation of the Potential for Drug Interactions by Salidroside

Safety of a Sustainably Produced, Bioengineered, Nature-Identical Salidroside Compound

STX140, but not paclitaxel, inhibits mammary tumour initiation and progression in C3(1)/SV40 T/t-antigen transgenic mice

IRC‐083864, a novel bis quinone inhibitor of CDC25 phosphatases active against human cancer cells

Inhibition of human tumor cell growth in vivo by an orally bioavailable inhibitor of CDC25 phosphatases

3,17-Disubstituted 2-Alkylestra-1,3,5(10)-trien-3-ol Derivatives: Synthesis, In Vitro and In Vivo Anticancer Activity

Tetrahydroisoquinolinone-Based Steroidomimetic and Chimeric Microtubule Disruptors

Synthesis, Antitubulin, and Antiproliferative SAR of C3/C1-Substituted Tetrahydroisoquinolines

Membrane structure modulation, protein kinase C alpha activation, and anticancer activity of minerval

Anticancer Activity of BIM-46174, a New Inhibitor of the Heterotrimeric G alpha /G beta gamma Protein Complex

2-MeOE2bisMATE and 2-EtE2bisMATE induce cell cycle arrest and apoptosis in breast cancer xenografts as shown by a novel ex vivo technique

Anticancer activity of BIM-46174, a new inhibitor of the heterotrimeric Gα/Gβγ protein complex

Homocamptothecins: Synthesis and Antitumor Activity of Novel E-Ring-Modified Camptothecin Analogues

Cover Picture: Tetrahydroisoquinolinone-Based Steroidomimetic and Chimeric Microtubule Disruptors (ChemMedChem 1/2014)

A novel synthetic inhibitor of CDC25 phosphatases: BN82002

IRC-083927 is a new tubulin binder that inhibits growth of human tumor cells resistant to standard tubulin-binding agents

IIn Vitro/I Evaluation of the Potential for Drug Interactions by Salidroside

Recombinant Anti-ErbB2 Immunotoxins Containing Pseudomonas Exotoxin

Therapy of an animal model of human gastric cancer using a combination of anti-erbB-2 monoclonal antibodies

AR36A36.11.1, a monoclonal antibody targeting CD59, enhances complement activity and exhibits potent in vivo efficacy in multiple human cancer models

A Novel Synthetic Inhibitor of CDC25 Phosphatases

A Mitogenic Peptide Amide Encoded within the E Peptide Domain of the Insulin-Like Growth Factor IB Prohormone

STX140, but Not Paclitaxel, Inhibits Mammary Tumour Initiation and Progression in C3

The homocamptothecin BN 80915 is a highly potent orally active topoisomerase I poison

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