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Chemical modification of hammerhead ribozymes. Catalytic activity and nuclease resistance

The Journal of biological chemistry, 1995-10, Vol.270 (43), p.25702-25708

1995

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Chemically Modified Hammerhead Ribozymes with Improved Catalytic Rates

Biochemistry (Easton), 1996-11, Vol.35 (45), p.14090-14097

1996

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Functional groups on the cleavage site pyrimidine nucleotide are required for stabilization of the hammerhead transition state

RNA (Cambridge), 1997-10, Vol.3 (10), p.1135-1142

1997

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Formation and properties of S-protein complex with S-peptide-containing fusion protein

FEBS letters, 1994, Vol.339 (3), p.209-212

1994

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Synthesis and properties of 3′- C-methylnucleosides and their phosphoric esters

Carbohydrate research, 1983-01, Vol.124 (1), p.75-96

1983

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A route to 2',5'-oligoadenylates with increased stability towards phosphodiesterases

Antimicrobial agents and chemotherapy, 1988, Vol.236 (2), p.325-328

1988

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New syntheses of 2'-C-methynucleosides starting from D-glucose and D-ribose

Carbohydrate research, 1987, Vol.166 (2), p.219-232

1987

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ChemInform Abstract: A New Scheme for the Synthesis of 5′‐Nucleotide Phosphonate Analogs

ChemInform, 1988-01, Vol.19 (3), p.no-no

1988

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ChemInform Abstract: New Syntheses of 2′‐C‐Methylnucleosides Starting from D‐Glucose and D‐Ribose

ChemInform, 1988-03, Vol.19 (10), p.no-no

1988

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Distinct mechanisms of bisphosphonate action between osteoblasts and breast cancer cells: identity of a potent new bisphosphonate analogue

Breast cancer research and treatment, 2002-02, Vol.71 (3), p.257-268

2002

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Base and sugar requirements for RNA cleavage of essential nucleoside residues in internal loop B of the hairpin ribozyme: implications for secondary structure

Nucleic acids research, 1996-02, Vol.24 (4), p.573

1996

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Ribozyme Catalysis from the Major Groove of Group II Intron Domain 5

Molecular cell, 1998-02, Vol.1 (3), p.433-441

1998

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Formation and properties of S-protein complex with S-peptide-containing fusion protein

FEBS letters, 1994-02, Vol.339 (3), p.209-212

1994

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Localization and analysis of nonpolar regions in onconase

Cellular and molecular life sciences : CMLS, 2000-08, Vol.57 (8-9), p.1306-1316

2000

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Optimizing the cell efficacy of synthetic ribozymes. Site selection and chemical modifications of ribozymes targeting the proto-oncogene c-myb

The Journal of biological chemistry, 1996-11, Vol.271 (46), p.29107-29112

1996

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Analysis of non-polar regions in proteins

Journal of molecular biology, 1992-04, Vol.224 (3), p.629-638

1992

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RNA cleavage without hydrolysis. Splitting the catalytic activities of binase with Asn101 and Thr101 mutations

Protein engineering, 1997-03, Vol.10 (3), p.273-278

1997

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Interaction of HIV-1 Reverse Transcriptase and T7 RNA Polymerase with Phosphonate Analogs of NTP and Inorganic Pyrophosphate

Molecular biology (New York), 2001-09, Vol.35 (5), p.717-729

2001

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Site-Specific Cross-Linking of Amino Acids in the Basic Region of Human Immunodeficiency Virus Type 1 Tat Peptide to Chemically Modified TAR RNA Duplexes

Biochemistry (Easton), 1998-03, Vol.37 (9), p.3096-3108

1998

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Biological activities of human interferon and 2'-5' oligoadenylates in plants

Plant molecular biology, 1992-11, Vol.20 (3), p.383-393

1992

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Investigation of the Proposed Interdomain Ribose Zipper in Hairpin Ribozyme Cleavage Using 2‘-Modified Nucleosides

Biochemistry (Easton), 2000-05, Vol.39 (21), p.6410-6421

2000

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Investigation of the Proposed Interdomain Ribose Zipper in Hairpin Ribozyme Cleavage Using 2‘-Modified Nucleosides

Biochemistry (Easton), 2001-06, Vol.40 (24), p.7350-7350

2001

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Intramolecular interactions in pancreatic ribonucleases

Protein science, 1992-08, Vol.1 (8), p.1050-1060

1992

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Site-directed mutagenesis of the base recognition loop of ribonuclease from Bacillus intermedius (binase)

FEBS letters, 1996-04, Vol.384 (2), p.143-146

1996

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Chemical modification of hammerhead ribozymes. Catalytic activity and nuclease resistance

Chemically Modified Hammerhead Ribozymes with Improved Catalytic Rates

Functional groups on the cleavage site pyrimidine nucleotide are required for stabilization of the hammerhead transition state

Formation and properties of S-protein complex with S-peptide-containing fusion protein

Synthesis and properties of 3′- C-methylnucleosides and their phosphoric esters

A route to 2',5'-oligoadenylates with increased stability towards phosphodiesterases

New syntheses of 2'-C-methynucleosides starting from D-glucose and D-ribose

ChemInform Abstract: A New Scheme for the Synthesis of 5′‐Nucleotide Phosphonate Analogs

ChemInform Abstract: New Syntheses of 2′‐C‐Methylnucleosides Starting from D‐Glucose and D‐Ribose

A promising approach for treatment of tumor-induced bone diseases: Utilizing bisphosphonate derivatives of nucleoside antimetabolites

Distinct mechanisms of bisphosphonate action between osteoblasts and breast cancer cells: identity of a potent new bisphosphonate analogue

Base and sugar requirements for RNA cleavage of essential nucleoside residues in internal loop B of the hairpin ribozyme: implications for secondary structure

Ribozyme Catalysis from the Major Groove of Group II Intron Domain 5

Formation and properties of S-protein complex with S-peptide-containing fusion protein

Localization and analysis of nonpolar regions in onconase

Optimizing the cell efficacy of synthetic ribozymes. Site selection and chemical modifications of ribozymes targeting the proto-oncogene c-myb

Analysis of non-polar regions in proteins

RNA cleavage without hydrolysis. Splitting the catalytic activities of binase with Asn101 and Thr101 mutations

Interaction of HIV-1 Reverse Transcriptase and T7 RNA Polymerase with Phosphonate Analogs of NTP and Inorganic Pyrophosphate

Site-Specific Cross-Linking of Amino Acids in the Basic Region of Human Immunodeficiency Virus Type 1 Tat Peptide to Chemically Modified TAR RNA Duplexes

Biological activities of human interferon and 2'-5' oligoadenylates in plants

Investigation of the Proposed Interdomain Ribose Zipper in Hairpin Ribozyme Cleavage Using 2‘-Modified Nucleosides

Investigation of the Proposed Interdomain Ribose Zipper in Hairpin Ribozyme Cleavage Using 2‘-Modified Nucleosides

Intramolecular interactions in pancreatic ribonucleases

Site-directed mutagenesis of the base recognition loop of ribonuclease from Bacillus intermedius (binase)

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