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Targeting the CD40-CD40L pathway in autoimmune diseases: Humoral immunity and beyond

Advanced drug delivery reviews, 2019-02, Vol.141, p.92-103

2019

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In or out of control: Modulating regulatory T cell homeostasis and function with immune checkpoint pathways

Frontiers in immunology, 2022-12, Vol.13, p.1033705-1033705

2022

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Galectin-9 inhibits TLR7-mediated autoimmunity in murine lupus models

The Journal of clinical investigation, 2018-05, Vol.128 (5), p.1873-1887

2018

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Mycophenolic acid differentially impacts B cell function depending on the stage of differentiation

The Journal of immunology (1950), 2011-10, Vol.187 (7), p.3603-3612

2011

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Quetiapine has an additive effect to triiodothyronine in inducing differentiation of oligodendrocyte precursor cells through induction of cholesterol biosynthesis

PloS one, 2019-09, Vol.14 (9), p.e0221747

2019

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Effects of CXCL13 inhibition on lymphoid follicles in models of autoimmune disease

European journal of clinical investigation, 2013-05, Vol.43 (5), p.501-509

2013

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Discovery and characterization of potent IL-21 neutralizing antibodies via a novel alternating antigen immunization and humanization strategy

PloS one, 2019-01, Vol.14 (1), p.e0211236-e0211236

2019

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Role of CD11c+ T-bet+ B cells in human health and disease

Cellular immunology, 2017-11, Vol.321, p.40-45

2017

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Pathogenic mechanisms of IgE-mediated inflammation in self-destructive autoimmune responses

Autoimmunity (Chur, Switzerland), 2017-02, Vol.50 (1), p.25-36

2017

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The Interplay of IL-21 and BAFF in the Formation and Maintenance of Human B Cell Memory

Frontiers in immunology, 2012-01, Vol.3, p.2-2

2012

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IL-21 drives expansion and plasma cell differentiation of autoreactive CD11chiT-bet+ B cells in SLE

Nature communications, 2018-05, Vol.9 (1), p.1-14, Article 1758

2018

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Self-reactive IgE exacerbates interferon responses associated with autoimmunity

Nature immunology, 2016-02, Vol.17 (2), p.196-203

2016

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B7-H7 (HHLA2) inhibits T-cell activation and proliferation in the presence of TCR and CD28 signaling

Cellular & molecular immunology, 2021-06, Vol.18 (6), p.1503-1511

2021

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A CD40L-targeting protein reduces autoantibodies and improves disease activity in patients with autoimmunity

Science translational medicine, 2019-04, Vol.11 (489)

2019

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Depleting plasmacytoid dendritic cells reduces local type I interferon responses and disease activity in patients with cutaneous lupus

Science translational medicine, 2021-05, Vol.13 (595)

2021

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CD19 and CD32b differentially regulate human B cell responsiveness

The Journal of immunology (1950), 2014-02, Vol.192 (4), p.1480-1490

2014

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SLE Plasma Profiling Identifies Unique Signatures of Lupus Nephritis and Discoid Lupus

Scientific reports, 2019-10, Vol.9 (1), p.14433-12, Article 14433

2019

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Discerning the kinetics of autoimmune manifestations in a model of Sjögren's syndrome

Molecular immunology, 2014-12, Vol.62 (2), p.277-282

2014

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Characterisation of anifrolumab, a fully human anti-interferon receptor antagonist antibody for the treatment of systemic lupus erythematosus

Lupus science & medicine, 2018-01, Vol.5 (1), p.e000261-e000261

2018

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Autoimmune manifestations in aged mice arise from early-life immune dysregulation

Science translational medicine, 2016-10, Vol.8 (361), p.361ra137

2016

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Distinct roles for PTEN in prevention of T cell lymphoma and autoimmunity in mice

The Journal of clinical investigation, 2010-07, Vol.120 (7), p.2497-2507

2010

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Comprehensive proteomic profiling of Sjogren’s syndrome revealed dysregulation of interferon and other immunologic pathways

The Journal of immunology (1950), 2017-05, Vol.198 (1_Supplement), p.55-55.17

2017

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Role and Regulation of CD11chi T-bet+ B cells in SLE

The Journal of immunology (1950), 2017-05, Vol.198 (1_Supplement), p.54-54.4

2017

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Effects of CXCL 13 inhibition on lymphoid follicles in models of autoimmune disease

European journal of clinical investigation, 2013-05, Vol.43 (5), p.501-509

2013

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IL-21 drives expansion and plasma cell differentiation of autoreactive CD11c hi T-bet + B cells in SLE

Nature communications, 2018-05, Vol.9 (1), p.1758

2018

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Targeting the CD40-CD40L pathway in autoimmune diseases: Humoral immunity and beyond

In or out of control: Modulating regulatory T cell homeostasis and function with immune checkpoint pathways

Galectin-9 inhibits TLR7-mediated autoimmunity in murine lupus models

Mycophenolic acid differentially impacts B cell function depending on the stage of differentiation

Quetiapine has an additive effect to triiodothyronine in inducing differentiation of oligodendrocyte precursor cells through induction of cholesterol biosynthesis

Effects of CXCL13 inhibition on lymphoid follicles in models of autoimmune disease

Discovery and characterization of potent IL-21 neutralizing antibodies via a novel alternating antigen immunization and humanization strategy

Role of CD11c+ T-bet+ B cells in human health and disease

Pathogenic mechanisms of IgE-mediated inflammation in self-destructive autoimmune responses

The Interplay of IL-21 and BAFF in the Formation and Maintenance of Human B Cell Memory

IL-21 drives expansion and plasma cell differentiation of autoreactive CD11chiT-bet+ B cells in SLE

Self-reactive IgE exacerbates interferon responses associated with autoimmunity

B7-H7 (HHLA2) inhibits T-cell activation and proliferation in the presence of TCR and CD28 signaling

A CD40L-targeting protein reduces autoantibodies and improves disease activity in patients with autoimmunity

Depleting plasmacytoid dendritic cells reduces local type I interferon responses and disease activity in patients with cutaneous lupus

CD19 and CD32b differentially regulate human B cell responsiveness

SLE Plasma Profiling Identifies Unique Signatures of Lupus Nephritis and Discoid Lupus

Discerning the kinetics of autoimmune manifestations in a model of Sjögren's syndrome

Characterisation of anifrolumab, a fully human anti-interferon receptor antagonist antibody for the treatment of systemic lupus erythematosus

Autoimmune manifestations in aged mice arise from early-life immune dysregulation

Distinct roles for PTEN in prevention of T cell lymphoma and autoimmunity in mice

Comprehensive proteomic profiling of Sjogren’s syndrome revealed dysregulation of interferon and other immunologic pathways

Role and Regulation of CD11chi T-bet+ B cells in SLE

Effects of CXCL 13 inhibition on lymphoid follicles in models of autoimmune disease

IL-21 drives expansion and plasma cell differentiation of autoreactive CD11c hi T-bet + B cells in SLE

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