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Carboxyamidotriazole-orotate inhibits the growth of imatinib-resistant chronic myeloid leukaemia cells and modulates exosomes-stimulated angiogenesis

PloS one, 2012-08, Vol.7 (8), p.e42310

2012

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Abstract A233: Pharmacodynamic Transcriptional markers of carboxyamidotriazole orotate (CTO) exposure in anagen hair

Molecular cancer therapeutics, 2013-11, Vol.12 (11_Supplement), p.A233-A233

2013

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Combinatorial treatment using CTO with paclitaxel or paclitaxel orotate in sc-implanted human OVCAR-5 ovarian tumor model

Journal of clinical oncology, 2012-05, Vol.30 (15_suppl), p.e15515-e15515

2012

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Combinatorial treatment with CTO and temozolomide in sc-implanted human LOX 1MVI melanoma

Journal of clinical oncology, 2012-05, Vol.30 (15_suppl), p.e19006-e19006

2012

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Multicenter Phase IB trial of carboxyamidotriazole orotate (CTO) combined with temozolomide (TMZ) for recurrent glioblastoma (GBM) and other malignant gliomas (MG)

Journal of clinical oncology, 2016-05, Vol.34 (15_suppl), p.2064-2064

2016

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Phase IB trial of carboxyamidotriazole orotate (CTO) and temozolomide for recurrent malignant glioma (MG): A novel mechanism for modulation of multiple oncogenic pathways

Journal of clinical oncology, 2014-05, Vol.32 (15_suppl), p.2071-2071

2014

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Phase 1 clinical trial of carboxyamidotriazole orotate (CTO) in combination with lomustine (CCNU) for adult patients with recurrent malignant glioma (MG)

Journal of clinical oncology, 2015-05, Vol.33 (15_suppl), p.e13004-e13004

2015

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Carboxyamidotriazole orotate (CTO) in combination with bevacizumab (BEV) for adult patients with recurrent malignant glioma post-BEV failure: Phase 1

Journal of clinical oncology, 2015-05, Vol.33 (15_suppl), p.2067-2067

2015

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Phase IB trial of carboxyamidotriazole orotate (CTO) and radiotherapy (RT) with concurrent and adjuvant temozolomide (TMZ) in newly diagnosed glioblastoma (GBM)

Journal of clinical oncology, 2016-05, Vol.34 (15_suppl), p.2060-2060

2016

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Comparative Response of SC CAKI-1 Renal Tumor to Treatment with Doxorubicin HCl and Doxorubicin Orotate

Journal of cancer therapy, 2014, Vol.5 (5), p.427-441

2014

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AT-48A PHASE 1 TRIAL OF CARBOXYAMIDOTRIAZOLE OROTATE (CTO) IN COMBINATION WITH BEVACIZUMAB FOR ADULT PATIENTS WITH RECURRENT MALIGNANT GLIOMA POST-BEVACIZUMAB FAILURE

Neuro-oncology (Charlottesville, Va.), 2014-11, Vol.16 (Suppl 5), p.v19-v19

2014

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Phase IB trial of carboxyamidotriazole orotate (CTO) and radiotherapy (RT) with concurrent and adjuvant temozolomide (TMZ) in newly diagnosed glioblastoma (GBM)

Journal of clinical oncology, 2015-05, Vol.33 (15_suppl), p.2062-2062

2015

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A phase I study of carboxyamidotriazole orotate (CTO) in of advanced solid tumors

Journal of clinical oncology, 2013-05, Vol.31 (15_suppl), p.2518-2518

2013

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Treatment with Paclitaxel Orotate and Carboxyamidotriazole Orotate in SC-Implanted OVCAR-5 Human Ovarian Tumor Xenografts

Journal of cancer therapy, 2013, Vol.4 (4), p.857-871

2013

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NI-57DYNAMIC CONTRAST-ENHANCED MAGNETIC RESONANCE PERFUSION WEIGHTED IMAGING (DCE-MRI) AND DIFFUSION WEIGHTED IMAGING (DWI) FOR PHARMACODYNAMIC EVALUATION OF CARBOXYAMIDOTRIAZOLE OROTATE (CTO) AND TEMOZOLOMIDE IN MALIGNANT GLIOMA

Neuro-oncology (Charlottesville, Va.), 2014-11, Vol.16 (Suppl 5), p.v150-v151

2014

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AT-48 A PHASE 1 TRIAL OF CARBOXYAMIDOTRIAZOLE OROTATE (CTO) IN COMBINATION WITH BEVACIZUMAB FOR ADULT PATIENTS WITH RECURRENT MALIGNANT GLIOMA POST-BEVACIZUMAB FAILURE

Neuro-oncology (Charlottesville, Va.), 2014-11, Vol.16 (suppl 5), p.v19-v19

2014

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NI-57 DYNAMIC CONTRAST-ENHANCED MAGNETIC RESONANCE PERFUSION WEIGHTED IMAGING (DCE-MRI) AND DIFFUSION WEIGHTED IMAGING (DWI) FOR PHARMACODYNAMIC EVALUATION OF CARBOXYAMIDOTRIAZOLE OROTATE (CTO) AND TEMOZOLOMIDE IN MALIGNANT GLIOMA

Neuro-oncology (Charlottesville, Va.), 2014-11, Vol.16 (suppl 5), p.v150-v151

2014

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Effect of Carboxyamidotriazole Orotate, a Modulator of Calcium-Dependent Signaling Pathways, on Advanced Solid Tumors

Journal of cancer therapy, 2015, Vol.6 (4), p.322-333

2015

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Combinatorial treatment with carboxyamidotriazole- orotate and temozolomide in sc-implanted human LOX IMVI melanoma xenografts

Journal of solid tumors, 2012-10, Vol.2 (5), p.13-13

2012

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Effect of flurbiprofen and 16,16-dimethyl prostaglandin E2 on gastrointestinal tumorigenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in rats: glandular epithelium of stomach and duodenum

Cancer research (Chicago, Ill.), 1990-01, Vol.50 (2), p.381-384

1990

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Historical perspective and potential use of n-3 fatty acids in therapy of cancer cachexia

Nutrition (Burbank, Los Angeles County, Calif.), 1996, Vol.12 (1), p.S2-S4

Karmali, Rashida A.

1996

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Influence of Exogenous Cyclic 3′: 5′-AMP on Growth, Prostaglandin Biosynthesis, and Prolactin Binding Capacity of Cultured Mammary Tumor Cells

Annals of the New York Academy of Sciences, 1986-05, Vol.463 (1), p.171-173

1986

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Effect of Omega-3 Fatty Acids on Growth of a Rat Mammary Tumor

JNCI : Journal of the National Cancer Institute, 1984-08, Vol.73 (2), p.457-461

1984

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Historical perspective and potential use of n-3 fatty acids in therapy of cancer cachexia

Nutrition (Burbank, Los Angeles County, Calif.), 1996, Vol.12, p.S2-S4

Karmali, Rashida A.

1996

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Multicenter Phase IB Trial of Carboxyamidotriazole Orotate and Temozolomide for Recurrent and Newly Diagnosed Glioblastoma and Other Anaplastic Gliomas

Carboxyamidotriazole-orotate inhibits the growth of imatinib-resistant chronic myeloid leukaemia cells and modulates exosomes-stimulated angiogenesis

Abstract A233: Pharmacodynamic Transcriptional markers of carboxyamidotriazole orotate (CTO) exposure in anagen hair

Combinatorial treatment using CTO with paclitaxel or paclitaxel orotate in sc-implanted human OVCAR-5 ovarian tumor model

Combinatorial treatment with CTO and temozolomide in sc-implanted human LOX 1MVI melanoma

Multicenter Phase IB trial of carboxyamidotriazole orotate (CTO) combined with temozolomide (TMZ) for recurrent glioblastoma (GBM) and other malignant gliomas (MG)

Phase IB trial of carboxyamidotriazole orotate (CTO) and temozolomide for recurrent malignant glioma (MG): A novel mechanism for modulation of multiple oncogenic pathways

Phase 1 clinical trial of carboxyamidotriazole orotate (CTO) in combination with lomustine (CCNU) for adult patients with recurrent malignant glioma (MG)

Carboxyamidotriazole orotate (CTO) in combination with bevacizumab (BEV) for adult patients with recurrent malignant glioma post-BEV failure: Phase 1

Phase IB trial of carboxyamidotriazole orotate (CTO) and radiotherapy (RT) with concurrent and adjuvant temozolomide (TMZ) in newly diagnosed glioblastoma (GBM)

Comparative Response of SC CAKI-1 Renal Tumor to Treatment with Doxorubicin HCl and Doxorubicin Orotate

AT-48A PHASE 1 TRIAL OF CARBOXYAMIDOTRIAZOLE OROTATE (CTO) IN COMBINATION WITH BEVACIZUMAB FOR ADULT PATIENTS WITH RECURRENT MALIGNANT GLIOMA POST-BEVACIZUMAB FAILURE

Phase IB trial of carboxyamidotriazole orotate (CTO) and radiotherapy (RT) with concurrent and adjuvant temozolomide (TMZ) in newly diagnosed glioblastoma (GBM)

A phase I study of carboxyamidotriazole orotate (CTO) in of advanced solid tumors

Treatment with Paclitaxel Orotate and Carboxyamidotriazole Orotate in SC-Implanted OVCAR-5 Human Ovarian Tumor Xenografts

NI-57DYNAMIC CONTRAST-ENHANCED MAGNETIC RESONANCE PERFUSION WEIGHTED IMAGING (DCE-MRI) AND DIFFUSION WEIGHTED IMAGING (DWI) FOR PHARMACODYNAMIC EVALUATION OF CARBOXYAMIDOTRIAZOLE OROTATE (CTO) AND TEMOZOLOMIDE IN MALIGNANT GLIOMA

AT-48 A PHASE 1 TRIAL OF CARBOXYAMIDOTRIAZOLE OROTATE (CTO) IN COMBINATION WITH BEVACIZUMAB FOR ADULT PATIENTS WITH RECURRENT MALIGNANT GLIOMA POST-BEVACIZUMAB FAILURE

NI-57 DYNAMIC CONTRAST-ENHANCED MAGNETIC RESONANCE PERFUSION WEIGHTED IMAGING (DCE-MRI) AND DIFFUSION WEIGHTED IMAGING (DWI) FOR PHARMACODYNAMIC EVALUATION OF CARBOXYAMIDOTRIAZOLE OROTATE (CTO) AND TEMOZOLOMIDE IN MALIGNANT GLIOMA

Effect of Carboxyamidotriazole Orotate, a Modulator of Calcium-Dependent Signaling Pathways, on Advanced Solid Tumors

Combinatorial treatment with carboxyamidotriazole- orotate and temozolomide in sc-implanted human LOX IMVI melanoma xenografts

Effect of flurbiprofen and 16,16-dimethyl prostaglandin E2 on gastrointestinal tumorigenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in rats: glandular epithelium of stomach and duodenum

Historical perspective and potential use of n-3 fatty acids in therapy of cancer cachexia

Influence of Exogenous Cyclic 3′: 5′-AMP on Growth, Prostaglandin Biosynthesis, and Prolactin Binding Capacity of Cultured Mammary Tumor Cells

Effect of Omega-3 Fatty Acids on Growth of a Rat Mammary Tumor

Historical perspective and potential use of n-3 fatty acids in therapy of cancer cachexia

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