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25 years and still going strong: 2′-O-(pyren-1-yl)methylribonucleotides - versatile building blocks for applications in molecular biology, diagnostics and materials science

Organic & biomolecular chemistry, 2017-11, Vol.15 (46), p.976-9774

2017

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Nicked Invader probes: multistranded and sequence-unrestricted recognition of double-stranded DNA

Organic & biomolecular chemistry, 2022-02, Vol.20 (5), p.1019-1030

2022

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Recognition of double-stranded DNA using LNA-modified toehold Invader probes

Organic & biomolecular chemistry, 2021-11, Vol.19 (42), p.9276-929

2021

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Factors Impacting Invader-Mediated Recognition of Double-Stranded DNA

Molecules (Basel, Switzerland), 2022-12, Vol.28 (1), p.127

2022

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Invader probes: Harnessing the energy of intercalation to facilitate recognition of chromosomal DNA for diagnostic applications

Chemical science (Cambridge), 2015-08, Vol.6 (8), p.5006-5015

2015

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Mixed-Sequence Recognition of Double-Stranded DNA Using Enzymatically Stable Phosphorothioate Invader Probes

Molecules (Basel, Switzerland), 2015-07, Vol.20 (8), p.13780-13793

2015

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Identification and Characterization of Second-Generation Invader Locked Nucleic Acids (LNAs) for Mixed-Sequence Recognition of Double-Stranded DNA

Journal of organic chemistry, 2013-10, Vol.78 (19), p.9560-9570

2013

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New Organocatalyst Scaffolds with High Activity in Promoting Hydrazone and Oxime Formation at Neutral pH

Organic letters, 2015-01, Vol.17 (2), p.274-277

2015

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Serine-γPNA, Invader probes, and chimeras thereof: three probe chemistries that enable sequence-unrestricted recognition of double-stranded DNA

Organic & biomolecular chemistry, 2022-11, Vol.2 (44), p.8714-8724

2022

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Understanding structure activity relationships of Good HEPES lipids for lipid nanoparticle mRNA vaccine applications

Biomaterials, 2023-10, Vol.301, p.122243-122243, Article 122243

2023

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Head-to-head comparison of LNA, γPNA, INA and Invader probes targeting mixed-sequence double-stranded DNA

Organic & biomolecular chemistry, 2020-01, Vol.18 (1), p.56-65

2020

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Bulged Invader probes: activated duplexes for mixed-sequence dsDNA recognition with improved thermodynamic and kinetic profiles

Chemical communications (Cambridge, England), 2015-10, Vol.51 (81), p.15051-15054

2015

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Inhalable dry powder product (DPP) of mRNA lipid nanoparticles (LNPs) for pulmonary delivery

Drug delivery and translational research, 2024-02, Vol.14 (2), p.360-372

2024

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Synthesis and biophysical characterization of oligonucleotides modified with O2′-alkylated RNA monomers featuring substituted pyrene moietiesElectronic supplementary information (ESI) available: General experimental section; protocol for synthesis of 7-neo-pentyl-1-pyrenemethanol and 7-tert-butyl-1-methoxy-5-pyrenemethanol; MS data for modified ONs; representative thermal denaturation curves; additional denaturation and thermodynamic data; additional absorption and steady-state fluorescence emis

2019-01

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DNA strands with alternating incorporations of LNA and 2′-O-(pyren-1-yl)methyluridine: SNP-discriminating RNA detection probes

Chemical science (Cambridge), 2013-09, Vol.4 (9), p.3447

2013

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Recognition of mixed-sequence DNA targets using spermine-modified Invader probes

Organic & biomolecular chemistry, 2019-10, Vol.17 (39), p.8795-8799

2019

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Bulged Invader probes: activated duplexes for mixed-sequence dsDNA recognition with improved thermodynamic and kinetic profilesElectronic supplementary information (ESI) available: Experimental protocols; MS data for modified ONs; representative thermal denaturation curves; additional gel electrophoretograms, kinetics plots, and Tm and dsDNA-recognition data. See DOI: 10.1039/c5cc06264k

2015-09

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Impact of non-nucleotidic bulges on recognition of mixed-sequence dsDNA by pyrene-functionalized Invader probes

Organic & biomolecular chemistry, 2020-06, Vol.18 (24), p.4645-4655

2020

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Recognition of mixed-sequence DNA using double-stranded probes with interstrand zipper arrangements of O2′-triphenylene- and coronene-functionalized RNA monomersElectronic supplementary information (ESI) available: General experimental section; MS-data for modified ONs; representative thermal denaturation curves; additional denaturation and thermodynamic data; additional steady-state fluorescence emission spectra; NMR spectra for nucleosides 2X, 3X and 4X. See DOI: 10.1039/c7ob01920c

2017-11

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Recognition of Mixed-Sequence DNA Duplexes: Design Guidelines for Invaders Based on 2′‑O‑(Pyren-1-yl)methyl-RNA Monomers

Journal of organic chemistry, 2013-12, Vol.78 (23), p.12040-12048

2013

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Recognition of mixed-sequence DNA using double-stranded probes with interstrand zipper arrangements of O2'-triphenylene- and coronene-functionalized RNA monomers

Organic & biomolecular chemistry, 2017-11, Vol.15 (44), p.9362-9371

2017

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Head-to-head comparison of LNA, MP γPNA, INA and Invader probes targeting mixed-sequence double-stranded DNA

Organic & biomolecular chemistry, 2020-01, Vol.18 (1), p.56-65

2020

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Sandwich assay for mixed-sequence recognition of double-stranded DNA: invader-based detection of targets specific to foodborne pathogens

Chemical communications (Cambridge, England), 2013-10, Vol.49 (84), p.9851-9853

2013

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Synthesis and biophysical characterization of oligonucleotides modified with O2'-alkylated RNA monomers featuring substituted pyrene moieties

Organic & biomolecular chemistry, 2019-01, Vol.17 (3), p.609-621

2019

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Organocatalytic removal of formaldehyde adducts from RNA and DNA bases

Nature chemistry, 2015-09, Vol.7 (9), p.752-758

2015

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25 years and still going strong: 2′-O-(pyren-1-yl)methylribonucleotides - versatile building blocks for applications in molecular biology, diagnostics and materials science

Nicked Invader probes: multistranded and sequence-unrestricted recognition of double-stranded DNA

Recognition of double-stranded DNA using LNA-modified toehold Invader probes

Factors Impacting Invader-Mediated Recognition of Double-Stranded DNA

Invader probes: Harnessing the energy of intercalation to facilitate recognition of chromosomal DNA for diagnostic applications

Mixed-Sequence Recognition of Double-Stranded DNA Using Enzymatically Stable Phosphorothioate Invader Probes

Identification and Characterization of Second-Generation Invader Locked Nucleic Acids (LNAs) for Mixed-Sequence Recognition of Double-Stranded DNA

New Organocatalyst Scaffolds with High Activity in Promoting Hydrazone and Oxime Formation at Neutral pH

Serine-γPNA, Invader probes, and chimeras thereof: three probe chemistries that enable sequence-unrestricted recognition of double-stranded DNA

Understanding structure activity relationships of Good HEPES lipids for lipid nanoparticle mRNA vaccine applications

Head-to-head comparison of LNA, γPNA, INA and Invader probes targeting mixed-sequence double-stranded DNA

Bulged Invader probes: activated duplexes for mixed-sequence dsDNA recognition with improved thermodynamic and kinetic profiles

Inhalable dry powder product (DPP) of mRNA lipid nanoparticles (LNPs) for pulmonary delivery

DNA strands with alternating incorporations of LNA and 2′-O-(pyren-1-yl)methyluridine: SNP-discriminating RNA detection probes

Recognition of mixed-sequence DNA targets using spermine-modified Invader probes

Impact of non-nucleotidic bulges on recognition of mixed-sequence dsDNA by pyrene-functionalized Invader probes

Recognition of Mixed-Sequence DNA Duplexes: Design Guidelines for Invaders Based on 2′‑O‑(Pyren-1-yl)methyl-RNA Monomers

Recognition of mixed-sequence DNA using double-stranded probes with interstrand zipper arrangements of O2'-triphenylene- and coronene-functionalized RNA monomers

Head-to-head comparison of LNA, MP γPNA, INA and Invader probes targeting mixed-sequence double-stranded DNA

Sandwich assay for mixed-sequence recognition of double-stranded DNA: invader-based detection of targets specific to foodborne pathogens

Synthesis and biophysical characterization of oligonucleotides modified with O2'-alkylated RNA monomers featuring substituted pyrene moieties

Organocatalytic removal of formaldehyde adducts from RNA and DNA bases

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