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The translation of cell-based therapies: clinical landscape and manufacturing challenges

Regenerative medicine, 2015-01, Vol.10 (1), p.49-64

2015

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Development of a process control strategy for the serum-free microcarrier expansion of human mesenchymal stem cells towards cost-effective and commercially viable manufacturing

Biochemical engineering journal, 2019-01, Vol.141, p.200-209

2019

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Characterization of human mesenchymal stem cells from multiple donors and the implications for large scale bioprocess development

Biochemical engineering journal, 2016-04, Vol.108, p.14-23

2016

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Generation and characterization of multipotent stem cells from established dermal cultures

PloS one, 2012-11, Vol.7 (11), p.e50742-e50742

2012

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Assessment of Protocol Impact on Subjectivity Uncertainty When Analyzing Peripheral Blood Mononuclear Cell Flow Cytometry Data Files

Methods and protocols, 2021-03, Vol.4 (2), p.24

2021

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Multivariate data analysis in cell gene therapy manufacturing

Biotechnology advances, 2020-12, Vol.45, p.107637-107637, Article 107637

2020

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Human hair follicle dermal sheath and papilla cells support keratinocyte growth in monolayer coculture

Experimental dermatology, 2013-03, Vol.22 (3), p.236-238

2013

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Lentiviral vector bioprocess economics for cell and gene therapy commercialization

Biochemical engineering journal, 2021-03, Vol.167, p.107868, Article 107868

2021

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Gene therapy process change evaluation framework: Transient transfection and stable producer cell line comparison

Biochemical engineering journal, 2021-12, Vol.176, p.108202, Article 108202

2021

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Expansion, harvest and cryopreservation of human mesenchymal stem cells in a serum-free microcarrier process

Biotechnology and bioengineering, 2015-08, Vol.112 (8), p.1696-1707

2015

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Agitation and aeration of stirred-bioreactors for the microcarrier culture of human mesenchymal stem cells and potential implications for large-scale bioprocess development

Biochemical engineering journal, 2018-08, Vol.136, p.9-17

2018

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Understanding the contribution of operator measurement variability within Flow Cytometry data analysis for Quality Control of Cell and Gene Therapy manufacturing

Measurement : journal of the International Measurement Confederation, 2020-01, Vol.150, p.106998, Article 106998

2020

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Scalability and process transfer of mesenchymal stromal cell production from monolayer to microcarrier culture using human platelet lysate

Cytotherapy (Oxford, England), 2016-04, Vol.18 (4), p.523-535

2016

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Serum-free process development: improving the yield and consistency of human mesenchymal stromal cell production

Cytotherapy (Oxford, England), 2015-11, Vol.17 (11), p.1524-1535

2015

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Studies related to antibody fragment (Fab) production in Escherichia coli W3110 fed-batch fermentation processes using multiparameter flow cytometry

Cytometry. Part A, 2009-02, Vol.75A (2), p.148-154

2009

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Novel systems for rapid fermentation process development of biopharmaceuticals

Journal of biotechnology, 2007-09, Vol.131 (2), p.S153-S153

2007

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Utilisation of key descriptors from protein sequence data to aid bioprocess route selection

Food and bioproducts processing, 2012-10, Vol.90 (4), p.755-761

2012

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Rapid analysis of the expression of heterologous proteins in Escherichia coli using pyrolysis mass spectrometry and Fourier transform infrared spectroscopy with chemometrics: application to alpha 2-interferon production

Journal of biotechnology, 1999-07, Vol.72 (3), p.157-167

1999

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On data-based modelling techniques for fermentation processes

Process biochemistry (1991), 1996, Vol.31 (2), p.147-155

1996

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Application of radial basis function and feedforward artificial neural networks to the Escherichia coli fermentation process

Neurocomputing (Amsterdam), 1998-08, Vol.20 (1), p.67-82

1998

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Structure of a specific peptide complex of the carboxy‐terminal SH2 domain from the p85 alpha subunit of phosphatidylinositol 3‐kinase

The EMBO journal, 1996-07, Vol.15 (14), p.3579-3589

1996

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Secondary Structure and Backbone Dynamics of Human Granulocyte Colony-Stimulating Factor in Solution

Biochemistry (Easton), 1994-06, Vol.33 (23), p.7184-7192

1994

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Comparing Different Modelling Techniques for the Escherichia Coli Fermentation Process

IFAC Proceedings Volumes, 1995-05, Vol.28 (3), p.142-147

1995

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COMPARING DIFFERENT MODELLING TECHNIQUES FOR THE ESCHERICHIA COLI FERMENTATION PROCESS

Computer Applications in Biotechnology, 1995, p.142-147

1995

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Global burden of stroke and risk factors in 188 countries, during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

Lancet neurology, 2016-08, Vol.15 (9), p.913-924

2016

Volltextzugriff (PDF)

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The translation of cell-based therapies: clinical landscape and manufacturing challenges

Development of a process control strategy for the serum-free microcarrier expansion of human mesenchymal stem cells towards cost-effective and commercially viable manufacturing

Characterization of human mesenchymal stem cells from multiple donors and the implications for large scale bioprocess development

Generation and characterization of multipotent stem cells from established dermal cultures

Assessment of Protocol Impact on Subjectivity Uncertainty When Analyzing Peripheral Blood Mononuclear Cell Flow Cytometry Data Files

Multivariate data analysis in cell gene therapy manufacturing

Human hair follicle dermal sheath and papilla cells support keratinocyte growth in monolayer coculture

Lentiviral vector bioprocess economics for cell and gene therapy commercialization

Gene therapy process change evaluation framework: Transient transfection and stable producer cell line comparison

Expansion, harvest and cryopreservation of human mesenchymal stem cells in a serum-free microcarrier process

Agitation and aeration of stirred-bioreactors for the microcarrier culture of human mesenchymal stem cells and potential implications for large-scale bioprocess development

Understanding the contribution of operator measurement variability within Flow Cytometry data analysis for Quality Control of Cell and Gene Therapy manufacturing

Scalability and process transfer of mesenchymal stromal cell production from monolayer to microcarrier culture using human platelet lysate

Serum-free process development: improving the yield and consistency of human mesenchymal stromal cell production

Studies related to antibody fragment (Fab) production in Escherichia coli W3110 fed-batch fermentation processes using multiparameter flow cytometry

Novel systems for rapid fermentation process development of biopharmaceuticals

Utilisation of key descriptors from protein sequence data to aid bioprocess route selection

Rapid analysis of the expression of heterologous proteins in Escherichia coli using pyrolysis mass spectrometry and Fourier transform infrared spectroscopy with chemometrics: application to alpha 2-interferon production

On data-based modelling techniques for fermentation processes

Application of radial basis function and feedforward artificial neural networks to the Escherichia coli fermentation process

Structure of a specific peptide complex of the carboxy‐terminal SH2 domain from the p85 alpha subunit of phosphatidylinositol 3‐kinase

Secondary Structure and Backbone Dynamics of Human Granulocyte Colony-Stimulating Factor in Solution

Comparing Different Modelling Techniques for the Escherichia Coli Fermentation Process

COMPARING DIFFERENT MODELLING TECHNIQUES FOR THE ESCHERICHIA COLI FERMENTATION PROCESS

Global burden of stroke and risk factors in 188 countries, during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

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