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Enlightening amyloid fibrils linked to type 2 diabetes and cross-interactions with Aβ

Nature structural & molecular biology, 2020-11, Vol.27 (11), p.1006-1008

Kapurniotu, Aphrodite

2020

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The Human Host‐Defense Peptide Cathelicidin LL‐37 is a Nanomolar Inhibitor of Amyloid Self‐Assembly of Islet Amyloid Polypeptide (IAPP)

Angewandte Chemie International Edition, 2020-07, Vol.59 (31), p.12837-12841

International ed. in English, 2020

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The Multitasking Potential of Alarmins and Atypical Chemokines

Frontiers in medicine, 2019-01, Vol.6, p.3-3

2019

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Strategien zur Inhibition der Protein-aggregation bei Amyloidkrankheiten

Biospektrum, 2012-11, Vol.18 (7), p.734-736

Kapurniotu, Aphrodite

2012

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Designed Macrocyclic Peptides as Nanomolar Amyloid Inhibitors Based on Minimal Recognition Elements

Angewandte Chemie International Edition, 2018-10, Vol.57 (44), p.14503-14508

International ed. in English, 2018

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Key aromatic/hydrophobic amino acids controlling a cross-amyloid peptide interaction versus amyloid self-assembly

The Journal of biological chemistry, 2017-09, Vol.292 (35), p.14587-14602

2017

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Molecular characterization of the hetero-assembly of β-amyloid peptide with islet amyloid polypeptide

Current pharmaceutical design, 2014-03, Vol.20 (8), p.1182-1191

2014

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Macrophage migration inhibitory factor (MIF) and its homolog D-dopachrome tautomerase (D-DT) are significant promotors of UVB- but not chemically induced non-melanoma skin cancer

Scientific reports, 2023-07, Vol.13 (1), p.11611-11611, Article 11611

2023

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Structural determinants of MIF functions in CXCR2-mediated inflammatory and atherogenic leukocyte recruitment

Proceedings of the National Academy of Sciences - PNAS, 2008-10, Vol.105 (42), p.16278-16283

2008

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Mif‐deficiency favors an atheroprotective autoantibody phenotype in atherosclerosis

The FASEB journal, 2018-08, Vol.32 (8), p.4428-4443

2018

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Peptide‐Based Molecular Strategies To Interfere with Protein Misfolding, Aggregation, and Cell Degeneration

Angewandte Chemie International Edition, 2020-02, Vol.59 (9), p.3372-3384

International ed. in English, 2020

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Suppression of IAPP fibrillation at anionic lipid membranes via IAPP-derived amyloid inhibitors and insulin

Biophysical chemistry, 2010-08, Vol.150 (1-3), p.73-79

2010

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Amyloidogenicity and cytotoxicity of islet amyloid polypeptide

Biopolymers, 2001, Vol.60 (6), p.438-459

Kapurniotu, Aphrodite

2001

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Structure-based design and study of non-amyloidogenic, double N-methylated IAPP amyloid core sequences as inhibitors of IAPP amyloid formation and cytotoxicity

Journal of molecular biology, 2002, Vol.315 (3), p.339-350

2002

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Interaction between amyloid beta peptide and an aggregation blocker peptide mimicking islet amyloid polypeptide

PloS one, 2011-05, Vol.6 (5), p.e20289-e20289

2011

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Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1

Nature (London), 2000-11, Vol.408 (6809), p.211-216

2000

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Cytotoxicity of Insulin within its Self-assembly and Amyloidogenic Pathways

Journal of molecular biology, 2007-07, Vol.370 (2), p.372-384

2007

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Development of Accessible Peptidic Tool Compounds To Study the Phosphatase PTP1B in Intact Cells

ACS chemical biology, 2014-03, Vol.9 (3), p.769-776

2014

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Conformational transitions of islet amyloid polypeptide (IAPP) in amyloid formation in Vitro

Journal of molecular biology, 1999-04, Vol.287 (4), p.781-796

1999

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Shedding Light on Alzheimer's β-Amyloid Aggregation with Chemical Tools

Chembiochem : a European journal of chemical biology, 2012-01, Vol.13 (1), p.27-29

Kapurniotu, Aphrodite

2012

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Disulfide analysis reveals a role for macrophage migration inhibitory factor (MIF) as thiol-protein oxidoreductase

Journal of molecular biology, 1998-07, Vol.280 (1), p.85-102

1998

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Macrophage Migration Inhibitory Factor (MIF)-Based Therapeutic Concepts in Atherosclerosis and Inflammation

Thrombosis and haemostasis, 2019-04, Vol.119 (4), p.553-566

2019

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Iris Antes 1969-2021

Bioinformatics advances, 2022-01, Vol.2 (1), p.vbac024-vbac024

2022

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Terminating the Amyloid Zipper by Design

Angewandte Chemie (International ed.), 2011-11, Vol.50 (48), p.11293-11294

Kapurniotu, Aphrodite

International ed. in English, 2011

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Contribution of conformationally constrained calcitonin (Ct) analogs to the understanding of the structural and conformational requirements of calcitonin bioactivity and to the design of potent agonists

Current medicinal chemistry, 2004-11, Vol.11 (21), p.2845-2865

Kapurniotu, Aphrodite

2004

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Enlightening amyloid fibrils linked to type 2 diabetes and cross-interactions with Aβ

The Human Host‐Defense Peptide Cathelicidin LL‐37 is a Nanomolar Inhibitor of Amyloid Self‐Assembly of Islet Amyloid Polypeptide (IAPP)

The Multitasking Potential of Alarmins and Atypical Chemokines

Strategien zur Inhibition der Protein-aggregation bei Amyloidkrankheiten

Designed Macrocyclic Peptides as Nanomolar Amyloid Inhibitors Based on Minimal Recognition Elements

Key aromatic/hydrophobic amino acids controlling a cross-amyloid peptide interaction versus amyloid self-assembly

Molecular characterization of the hetero-assembly of β-amyloid peptide with islet amyloid polypeptide

Macrophage migration inhibitory factor (MIF) and its homolog D-dopachrome tautomerase (D-DT) are significant promotors of UVB- but not chemically induced non-melanoma skin cancer

Structural determinants of MIF functions in CXCR2-mediated inflammatory and atherogenic leukocyte recruitment

Mif‐deficiency favors an atheroprotective autoantibody phenotype in atherosclerosis

Peptide‐Based Molecular Strategies To Interfere with Protein Misfolding, Aggregation, and Cell Degeneration

Suppression of IAPP fibrillation at anionic lipid membranes via IAPP-derived amyloid inhibitors and insulin

Amyloidogenicity and cytotoxicity of islet amyloid polypeptide

Structure-based design and study of non-amyloidogenic, double N-methylated IAPP amyloid core sequences as inhibitors of IAPP amyloid formation and cytotoxicity

Interaction between amyloid beta peptide and an aggregation blocker peptide mimicking islet amyloid polypeptide

Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1

Cytotoxicity of Insulin within its Self-assembly and Amyloidogenic Pathways

Development of Accessible Peptidic Tool Compounds To Study the Phosphatase PTP1B in Intact Cells

Conformational transitions of islet amyloid polypeptide (IAPP) in amyloid formation in Vitro

Shedding Light on Alzheimer's β-Amyloid Aggregation with Chemical Tools

Disulfide analysis reveals a role for macrophage migration inhibitory factor (MIF) as thiol-protein oxidoreductase

Macrophage Migration Inhibitory Factor (MIF)-Based Therapeutic Concepts in Atherosclerosis and Inflammation

Iris Antes 1969-2021

Terminating the Amyloid Zipper by Design

Contribution of conformationally constrained calcitonin (Ct) analogs to the understanding of the structural and conformational requirements of calcitonin bioactivity and to the design of potent agonists

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