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An agent cleaving glucose-derived protein crosslinks in vitro and in vivo

Nature (London), 1996-07, Vol.382 (6588), p.275-278

1996

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Designed CXCR4 mimic acts as a soluble chemokine receptor that blocks atherogenic inflammation by agonist-specific targeting

Nature communications, 2020-11, Vol.11 (1), p.5981-18, Article 5981

2020

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Design of a Mimic of Nonamyloidogenic and Bioactive Human Islet Amyloid Polypeptide (IAPP) as Nanomolar Affinity Inhibitor of IAPP Cytotoxic Fibrillogenesis

Proceedings of the National Academy of Sciences - PNAS, 2006-02, Vol.103 (7), p.2046-2051

2006

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Amyloidogenicity and cytotoxicity of islet amyloid polypeptide

Biopolymers, 2001, Vol.60 (6), p.438-459

Kapurniotu, Aphrodite

2001

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Rapid and transient activation of the ERK MAPK signalling pathway by macrophage migration inhibitory factor (MIF) and dependence on JAB1/CSN5 and Src kinase activity

Cellular signalling, 2006-05, Vol.18 (5), p.688-703

2006

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Structure-based design and study of non-amyloidogenic, double N-methylated IAPP amyloid core sequences as inhibitors of IAPP amyloid formation and cytotoxicity

Journal of molecular biology, 2002, Vol.315 (3), p.339-350

2002

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Heterocomplexes between the atypical chemokine MIF and the CXC-motif chemokine CXCL4L1 regulate inflammation and thrombus formation

Cellular and molecular life sciences : CMLS, 2022-10, Vol.79 (10), p.512-512, Article 512

2022

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Activated protein C inhibits tumor necrosis factor and macrophage migration inhibitory factor production in monocytes

European cytokine network (Montrouge), 2000-09, Vol.11 (3), p.407-413

2000

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A Novel Drug-Eluting Stent Coated With an Integrin-Binding Cyclic Arg-Gly-Asp Peptide Inhibits Neointimal Hyperplasia by Recruiting Endothelial Progenitor Cells

Journal of the American College of Cardiology, 2006-05, Vol.47 (9), p.1786-1795

2006

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Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1

Nature (London), 2000-11, Vol.408 (6809), p.211-216

2000

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Conformational transitions of islet amyloid polypeptide (IAPP) in amyloid formation in Vitro

Journal of molecular biology, 1999-04, Vol.287 (4), p.781-796

1999

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Identification of a penta- and hexapeptide of islet amyloid polypeptide (IAPP) with amyloidogenic and cytotoxic properties

Journal of molecular biology, 2000-01, Vol.295 (4), p.1055-1071

2000

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Disulfide analysis reveals a role for macrophage migration inhibitory factor (MIF) as thiol-protein oxidoreductase

Journal of molecular biology, 1998-07, Vol.280 (1), p.85-102

1998

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Contribution of conformationally constrained calcitonin (Ct) analogs to the understanding of the structural and conformational requirements of calcitonin bioactivity and to the design of potent agonists

Current medicinal chemistry, 2004-11, Vol.11 (21), p.2845-2865

Kapurniotu, Aphrodite

2004

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A 16-Residue Peptide Fragment of Macrophage Migration Inhibitory Factor, MIF-(50–65), Exhibits Redox Activity and Has MIF-like Biological Functions

The Journal of biological chemistry, 2003-09, Vol.278 (36), p.33654-33671

2003

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Macrophage Migration Inhibitory Factor Increases Neuronal Delayed Rectifier K+ Current

Journal of neurophysiology, 2006-02, Vol.95 (2), p.1042-1048

2006

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Specific reduction of insulin disulfides by macrophage migration inhibitory factor (MIF) with glutathione and dihydrolipoamide: potential role in cellular redox processes

FEBS letters, 1998-07, Vol.430 (3), p.191-196

1998

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[11] Advanced glycation end products: Detection and reversal

Methods in Enzymology, 1999, Vol.309, p.152-172

1999

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Structural and Conformational Requirements for Human Calcitonin Activity: Design, Synthesis, and Study of Lactam-Bridged Analogs

Journal of medicinal chemistry, 1995-03, Vol.38 (5), p.836-847

1995

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Charakterisierung und ex vivo physiologische Wirkung eines neu-entwickelten löslichen Amylin-Analogons

Zeitschrift für Gastroenterologie, 2013, Vol.51 (8)

2013

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Side-Chain Lactam-Bridge Conformational Constraints Differentiate the Activities of Salmon and Human Calcitonins and Reveal a New Design Concept for Potent Calcitonin Analogues

Journal of medicinal chemistry, 2002-02, Vol.45 (5), p.1108-1121

2002

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Structure activity studies of the cytokine macrophage migration inhibitory factor (MIF) reveal a critical role for its carboxy terminus

FEBS letters, 1997-09, Vol.414 (2), p.226-232

1997

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Characterization of catalytic centre mutants of macrophage migration inhibitory factor (MIF) and comparison to Cys81Ser MIF

European journal of biochemistry, 1999-05, Vol.261 (3), p.753-766

1999

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Conformationally constrained human calcitonin (hCt) analogues reveal a critical role of sequence 17–21 for the oligomerization state and bioactivity of hCt

European journal of biochemistry, 2002-02, Vol.269 (3), p.780-791

2002

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Targeting α-Synuclein in Parkinson's Disease

Chemistry & Biology, 2004-11, Vol.11 (11), p.1476-1478

Kapurniotu, Aphrodite

2004

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An agent cleaving glucose-derived protein crosslinks in vitro and in vivo

Designed CXCR4 mimic acts as a soluble chemokine receptor that blocks atherogenic inflammation by agonist-specific targeting

Design of a Mimic of Nonamyloidogenic and Bioactive Human Islet Amyloid Polypeptide (IAPP) as Nanomolar Affinity Inhibitor of IAPP Cytotoxic Fibrillogenesis

Amyloidogenicity and cytotoxicity of islet amyloid polypeptide

Rapid and transient activation of the ERK MAPK signalling pathway by macrophage migration inhibitory factor (MIF) and dependence on JAB1/CSN5 and Src kinase activity

Structure-based design and study of non-amyloidogenic, double N-methylated IAPP amyloid core sequences as inhibitors of IAPP amyloid formation and cytotoxicity

Heterocomplexes between the atypical chemokine MIF and the CXC-motif chemokine CXCL4L1 regulate inflammation and thrombus formation

Activated protein C inhibits tumor necrosis factor and macrophage migration inhibitory factor production in monocytes

A Novel Drug-Eluting Stent Coated With an Integrin-Binding Cyclic Arg-Gly-Asp Peptide Inhibits Neointimal Hyperplasia by Recruiting Endothelial Progenitor Cells

Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1

Conformational transitions of islet amyloid polypeptide (IAPP) in amyloid formation in Vitro

Identification of a penta- and hexapeptide of islet amyloid polypeptide (IAPP) with amyloidogenic and cytotoxic properties

Disulfide analysis reveals a role for macrophage migration inhibitory factor (MIF) as thiol-protein oxidoreductase

Contribution of conformationally constrained calcitonin (Ct) analogs to the understanding of the structural and conformational requirements of calcitonin bioactivity and to the design of potent agonists

A 16-Residue Peptide Fragment of Macrophage Migration Inhibitory Factor, MIF-(50–65), Exhibits Redox Activity and Has MIF-like Biological Functions

Macrophage Migration Inhibitory Factor Increases Neuronal Delayed Rectifier K+ Current

Specific reduction of insulin disulfides by macrophage migration inhibitory factor (MIF) with glutathione and dihydrolipoamide: potential role in cellular redox processes

[11] Advanced glycation end products: Detection and reversal

Structural and Conformational Requirements for Human Calcitonin Activity: Design, Synthesis, and Study of Lactam-Bridged Analogs

Charakterisierung und ex vivo physiologische Wirkung eines neu-entwickelten löslichen Amylin-Analogons

Side-Chain Lactam-Bridge Conformational Constraints Differentiate the Activities of Salmon and Human Calcitonins and Reveal a New Design Concept for Potent Calcitonin Analogues

Structure activity studies of the cytokine macrophage migration inhibitory factor (MIF) reveal a critical role for its carboxy terminus

Characterization of catalytic centre mutants of macrophage migration inhibitory factor (MIF) and comparison to Cys81Ser MIF

Conformationally constrained human calcitonin (hCt) analogues reveal a critical role of sequence 17–21 for the oligomerization state and bioactivity of hCt

Targeting α-Synuclein in Parkinson's Disease

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