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Diagnosis, management and prevention of drug-induced liver injury

Gut, 2009-11, Vol.58 (11), p.1555-1564

2009

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Case Definition and Phenotype Standardization in Drug-Induced Liver Injury

Clinical pharmacology and therapeutics, 2011-06, Vol.89 (6), p.806-815

2011

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JNK interaction with Sab mediates ER stress induced inhibition of mitochondrial respiration and cell death

Cell death & disease, 2014-01, Vol.5 (1), p.e989-e989

2014

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Drug-induced liver disorders. Implications for drug development and regulation

Drug safety, 2001, Vol.24 (7), p.483-490

KAPLOWITZ, Neil

2001

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Idiosyncratic drug hepatotoxicity

Nature reviews. Drug discovery, 2005-06, Vol.4 (6), p.489-499

Kaplowitz, Neil

2005

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Causality assessment versus guilt-by-association in drug hepatotoxicity

Hepatology (Baltimore, Md.), 2001, Vol.33 (1), p.308-310

Kaplowitz, Neil

2001

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In Vitro Assays of Mitochondrial Function/Dysfunction

Clinical pharmacology and therapeutics, 2014-12, Vol.96 (6), p.665-668

2014

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Is Sensitivity the Key Measure to Predict Acute Liver Failure in Drug-Induced Liver Injury Patients?

Clinical gastroenterology and hepatology, 2016-06, Vol.14 (6), p.918-918

2016

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Drug-Induced Liver Injury

Clinical infectious diseases, 2004-03, Vol.38 (Supplement-2), p.S44-S48

Kaplowitz, Neil

2004

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Recurrent Drug-Induced Liver Injury (DILI) with different drugs in the Spanish Registry: The dilemma of the relationship to autoimmune hepatitis

Journal of hepatology, 2011-10, Vol.55 (4), p.820-827

2011

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Hepatotoxicity of herbal remedies: Insights into the intricacies of plant-animal warfare and cell death

Gastroenterology (New York, N.Y. 1943), 1997-10, Vol.113 (4), p.1408-1412

Kaplowitz, N

1997

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Selective glutathione depletion of mitochondria by ethanol sensitizes hepatocytes to tumor necrosis factor

Gastroenterology (New York, N.Y. 1943), 1998-12, Vol.115 (6), p.1541-1551

1998

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Gut microbiota mediates diurnal variation of acetaminophen induced acute liver injury in mice

Journal of hepatology, 2018-07, Vol.69 (1), p.51-59

2018

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Mechanisms of liver cell injury

Journal of hepatology, 2000, Vol.32 (1 Suppl), p.39-47

Kaplowitz, Neil

2000

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Biochemical and Cellular Mechanisms of Toxic Liver Injury

Seminars in liver disease, 2002, Vol.22 (2), p.137-144

Kaplowitz, Neil

2002

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GSH transport in mitochondria: defense against TNF-induced oxidative stress and alcohol-induced defect

American journal of physiology: Gastrointestinal and liver physiology, 1997-07, Vol.273 (1 Pt 1), p.G7-G17

1997

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P338 ROLE OF ACID SPHINGOMYELINASE IN APAP-INDUCED LIVER INJURY

Journal of hepatology, 2014-04, Vol.60 (1), p.S179-S179

2014

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Acetaminophen hepatoxicity: What do we know, what don't we know, and what do we do next?

Hepatology (Baltimore, Md.), 2004-07, Vol.40 (1), p.23-26

Kaplowitz, Neil

2004

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Mechanisms of pathogenesis in drug hepatotoxicity putting the stress on mitochondria

Molecular interventions, 2010-04, Vol.10 (2), p.98-111

2010

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P309 PROGNOSTIC MODEL FOR PREDICTING DRUG-INDUCED ACUTE LIVER FAILURE

Journal of hepatology, 2014-04, Vol.60 (1), p.S169-S169

2014

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Cell death at the millennium. Implications for liver diseases

Clinics in liver disease, 2000-02, Vol.4 (1), p.1-23

Kaplowitz, N

2000

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Microcystin Uptake and Inhibition of Protein Phosphatases: Effects of Chemoprotectants and Self-Inhibition in Relation to Known Hepatic Transporters

Toxicology and applied pharmacology, 1995-10, Vol.134 (2), p.264-272

1995

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Role of JNK Translocation to Mitochondria Leading to Inhibition of Mitochondria Bioenergetics in Acetaminophen-induced Liver Injury

The Journal of biological chemistry, 2008-05, Vol.283 (20), p.13565-13577

2008

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Glycycoumarin protects mice against acetaminophen‐induced liver injury predominantly via activating sustained autophagy

British journal of pharmacology, 2018-10, Vol.175 (19), p.3747-3757

2018

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Role of oxidative stress generated from the mitochondrial electron transport chain and mitochondrial glutathione status in loss of mitochondrial function and activation of transcription factor nuclear factor-kappa B: studies with isolated mitochondria and rat hepatocytes

Molecular pharmacology, 1995-11, Vol.48 (5), p.825

1995

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Diagnosis, management and prevention of drug-induced liver injury

Case Definition and Phenotype Standardization in Drug-Induced Liver Injury

JNK interaction with Sab mediates ER stress induced inhibition of mitochondrial respiration and cell death

Drug-induced liver disorders. Implications for drug development and regulation

Idiosyncratic drug hepatotoxicity

Causality assessment versus guilt-by-association in drug hepatotoxicity

In Vitro Assays of Mitochondrial Function/Dysfunction

Is Sensitivity the Key Measure to Predict Acute Liver Failure in Drug-Induced Liver Injury Patients?

Drug-Induced Liver Injury

Recurrent Drug-Induced Liver Injury (DILI) with different drugs in the Spanish Registry: The dilemma of the relationship to autoimmune hepatitis

Hepatotoxicity of herbal remedies: Insights into the intricacies of plant-animal warfare and cell death

Selective glutathione depletion of mitochondria by ethanol sensitizes hepatocytes to tumor necrosis factor

Gut microbiota mediates diurnal variation of acetaminophen induced acute liver injury in mice

Mechanisms of liver cell injury

Biochemical and Cellular Mechanisms of Toxic Liver Injury

GSH transport in mitochondria: defense against TNF-induced oxidative stress and alcohol-induced defect

P338 ROLE OF ACID SPHINGOMYELINASE IN APAP-INDUCED LIVER INJURY

Acetaminophen hepatoxicity: What do we know, what don't we know, and what do we do next?

Mechanisms of pathogenesis in drug hepatotoxicity putting the stress on mitochondria

P309 PROGNOSTIC MODEL FOR PREDICTING DRUG-INDUCED ACUTE LIVER FAILURE

Cell death at the millennium. Implications for liver diseases

Microcystin Uptake and Inhibition of Protein Phosphatases: Effects of Chemoprotectants and Self-Inhibition in Relation to Known Hepatic Transporters

Role of JNK Translocation to Mitochondria Leading to Inhibition of Mitochondria Bioenergetics in Acetaminophen-induced Liver Injury

Glycycoumarin protects mice against acetaminophen‐induced liver injury predominantly via activating sustained autophagy

Role of oxidative stress generated from the mitochondrial electron transport chain and mitochondrial glutathione status in loss of mitochondrial function and activation of transcription factor nuclear factor-kappa B: studies with isolated mitochondria and rat hepatocytes

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