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Rescue Treatment with L-Citrulline Inhibits Hypoxia-Induced Pulmonary Hypertension in Newborn Pigs

American journal of respiratory cell and molecular biology, 2015-08, Vol.53 (2), p.255-264

2015

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Combined l-citrulline and tetrahydrobiopterin therapy improves NO signaling and ameliorates chronic hypoxia-induced pulmonary hypertension in newborn pigs

American journal of physiology. Lung cellular and molecular physiology, 2020-04, Vol.318 (4), p.L762-L772

2020

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Tetrahydrobiopterin oral therapy recouples eNOS and ameliorates chronic hypoxia-induced pulmonary hypertension in newborn pigs

American journal of physiology. Lung cellular and molecular physiology, 2016-10, Vol.311 (4), p.L743-L753

2016

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l‐Citrulline treatment alters the structure of the pulmonary circulation in hypoxic newborn pigs

Pediatric pulmonology, 2020-10, Vol.55 (10), p.2762-2772

2020

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Reactive oxygen species modulate Na + -coupled neutral amino acid transporter 1 expression in piglet pulmonary arterial endothelial cells

American journal of physiology. Heart and circulatory physiology, 2019-04, Vol.316 (4), p.H911-H919

2019

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Impact of l‐citrulline on nitric oxide signaling and arginase activity in hypoxic human pulmonary artery endothelial cells

Pulmonary circulation, 2023-04, Vol.13 (2), p.e12221-n/a

2023

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Folic acid, either solely or combined with L‐citrulline, improves NO signaling and ameliorates chronic hypoxia‐induced pulmonary hypertension in newborn pigs

Physiological reports, 2021-11, Vol.9 (21), p.e15096-n/a

2021

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L-citrulline increases arginase II protein levels and arginase activity in hypoxic piglet pulmonary artery endothelial cells

Pulmonary circulation, 2021-04, Vol.11 (2), p.1-10

2021

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Reactive oxygen species from NADPH oxidase contribute to altered pulmonary vascular responses in piglets with chronic hypoxia-induced pulmonary hypertension

American journal of physiology. Lung cellular and molecular physiology, 2008-11, Vol.295 (5), p.L881-L888

2008

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L-Citrulline ameliorates chronic hypoxia-induced pulmonary hypertension in newborn piglets

American journal of physiology. Lung cellular and molecular physiology, 2009-09, Vol.297 (3), p.L506-L511

2009

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Protein complex formation with heat shock protein 90 in chronic hypoxia-induced pulmonary hypertension in newborn piglets

American journal of physiology. Heart and circulatory physiology, 2010-10, Vol.299 (4), p.H1190-H1204

2010

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Pulmonary Arterial Responses to Reactive Oxygen Species Are Altered in Newborn Piglets With Chronic Hypoxia-Induced Pulmonary Hypertension

Pediatric research, 2011-08, Vol.70 (2), p.136-141

2011

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Heat shock protein 90-eNOS interactions mature with postnatal age in the pulmonary circulation of the piglet

American journal of physiology. Lung cellular and molecular physiology, 2009-03, Vol.296 (3), p.L555-L564

2009

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Thromboxane inhibition reduces an early stage of chronic hypoxia-induced pulmonary hypertension in piglets

Journal of applied physiology (1985), 2005-08, Vol.99 (2), p.670-676

2005

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Chronic hypoxia decreases nitric oxide production and endothelial nitric oxide synthase in newborn pig lungs

American journal of physiology. Lung cellular and molecular physiology, 1998-04, Vol.274 (4), p.517-L526

1998

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Voltage-gated K+ channels at an early stage of chronic hypoxia-induced pulmonary hypertension in newborn piglets

American journal of physiology. Lung cellular and molecular physiology, 2006-12, Vol.291 (6), p.L1169-L1176

2006

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A potential therapeutic role for angiotensin-converting enzyme 2 in human pulmonary arterial hypertension

The European respiratory journal, 2018-06, Vol.51 (6), p.1702638-1702638

2018

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Impaired NO signaling in small pulmonary arteries of chronically hypoxic newborn piglets

American journal of physiology. Lung cellular and molecular physiology, 2004-06, Vol.286 (6), p.L1244-L1254

2004

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Cyclooxygenase-2 and an early stage of chronic hypoxia-induced pulmonary hypertension in newborn pigs

Journal of applied physiology (1985), 2005-03, Vol.98 (3), p.1111-1118

2005

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Reactive oxygen species scavengers improve voltage-gated K+ channel function in pulmonary arteries of newborn pigs with progressive hypoxia-induced pulmonary hypertension

Pulmonary circulation, 2013-09, Vol.3 (3), p.551-563

2013

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Sildenafil and an early stage of chronic hypoxia-induced pulmonary hypertension in newborn piglets

Pediatric pulmonology, 2005-07, Vol.40 (1), p.72-80

2005

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Cyclooxygenase contracting factors and altered pulmonary vascular responses in chronically hypoxic newborn pigs

Journal of applied physiology (1985), 2002-01, Vol.92 (1), p.67-74

2002

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Chronic hypoxia alters nitric oxide-dependent pulmonary vascular responses in lungs of newborn pigs

Journal of applied physiology (1985), 1996-11, Vol.81 (5), p.2078-2087

1996

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Superoxide and Chronic Hypoxia-Induced Pulmonary Hypertension in Newborn Piglets

Chest, 2005-12, Vol.128 (6), p.555S-556S

2005

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L-Arginine increases nitric oxide production in isolated lungs of chronically hypoxic newborn pigs

Journal of applied physiology (1985), 2000-05, Vol.88 (5), p.1797-1803

2000

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Rescue Treatment with L-Citrulline Inhibits Hypoxia-Induced Pulmonary Hypertension in Newborn Pigs

Combined l-citrulline and tetrahydrobiopterin therapy improves NO signaling and ameliorates chronic hypoxia-induced pulmonary hypertension in newborn pigs

Tetrahydrobiopterin oral therapy recouples eNOS and ameliorates chronic hypoxia-induced pulmonary hypertension in newborn pigs

l‐Citrulline treatment alters the structure of the pulmonary circulation in hypoxic newborn pigs

Reactive oxygen species modulate Na + -coupled neutral amino acid transporter 1 expression in piglet pulmonary arterial endothelial cells

Impact of l‐citrulline on nitric oxide signaling and arginase activity in hypoxic human pulmonary artery endothelial cells

Folic acid, either solely or combined with L‐citrulline, improves NO signaling and ameliorates chronic hypoxia‐induced pulmonary hypertension in newborn pigs

L-citrulline increases arginase II protein levels and arginase activity in hypoxic piglet pulmonary artery endothelial cells

Reactive oxygen species from NADPH oxidase contribute to altered pulmonary vascular responses in piglets with chronic hypoxia-induced pulmonary hypertension

L-Citrulline ameliorates chronic hypoxia-induced pulmonary hypertension in newborn piglets

Protein complex formation with heat shock protein 90 in chronic hypoxia-induced pulmonary hypertension in newborn piglets

Pulmonary Arterial Responses to Reactive Oxygen Species Are Altered in Newborn Piglets With Chronic Hypoxia-Induced Pulmonary Hypertension

Heat shock protein 90-eNOS interactions mature with postnatal age in the pulmonary circulation of the piglet

Thromboxane inhibition reduces an early stage of chronic hypoxia-induced pulmonary hypertension in piglets

Chronic hypoxia decreases nitric oxide production and endothelial nitric oxide synthase in newborn pig lungs

Voltage-gated K+ channels at an early stage of chronic hypoxia-induced pulmonary hypertension in newborn piglets

A potential therapeutic role for angiotensin-converting enzyme 2 in human pulmonary arterial hypertension

Impaired NO signaling in small pulmonary arteries of chronically hypoxic newborn piglets

Cyclooxygenase-2 and an early stage of chronic hypoxia-induced pulmonary hypertension in newborn pigs

Reactive oxygen species scavengers improve voltage-gated K+ channel function in pulmonary arteries of newborn pigs with progressive hypoxia-induced pulmonary hypertension

Sildenafil and an early stage of chronic hypoxia-induced pulmonary hypertension in newborn piglets

Cyclooxygenase contracting factors and altered pulmonary vascular responses in chronically hypoxic newborn pigs

Chronic hypoxia alters nitric oxide-dependent pulmonary vascular responses in lungs of newborn pigs

Superoxide and Chronic Hypoxia-Induced Pulmonary Hypertension in Newborn Piglets

L-Arginine increases nitric oxide production in isolated lungs of chronically hypoxic newborn pigs

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