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The Worst Things in Life are Free: The Role of Free Heme in Sickle Cell Disease

Frontiers in immunology, 2021-01, Vol.11, p.561917

2021

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Global methylation patterns in idiopathic pulmonary fibrosis

PloS one, 2012-04, Vol.7 (4), p.e33770-e33770

2012

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Aging Mesenchymal Stem Cells Fail to Protect Because of Impaired Migration and Antiinflammatory Response

American journal of respiratory and critical care medicine, 2014-04, Vol.189 (7), p.787-798

2014

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Influence of age on wound healing and fibrosis

The Journal of pathology, 2013-01, Vol.229 (2), p.310-322

2013

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Early events marking lung fibroblast transition to profibrotic state in idiopathic pulmonary fibrosis

Respiratory research, 2023-04, Vol.24 (1), p.116-116, Article 116

2023

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Heme Induces IL-6 and Cardiac Hypertrophy Genes Transcripts in Sickle Cell Mice

Frontiers in immunology, 2020-08, Vol.11, p.1910-1910

2020

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The Cullin 4B-Based UV-Damaged DNA-Binding Protein Ligase Binds to UV-Damaged Chromatin and Ubiquitinates Histone H2A

Cancer research (Chicago, Ill.), 2008-07, Vol.68 (13), p.5014-5022

2008

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Expression of regulatory platelet microRNAs in patients with sickle cell disease

PloS one, 2013-04, Vol.8 (4), p.e60932

2013

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Modified mesenchymal stem cells using miRNA transduction alter lung injury in a bleomycin model

American journal of physiology. Lung cellular and molecular physiology, 2017-07, Vol.313 (1), p.L92-L103

2017

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The DNA transposon Minos as a tool for transgenesis and functional genomic analysis in vertebrates and invertebrates

Genome biology, 2007-01, Vol.8 Suppl 1 (Suppl 1), p.S2-S2

2007

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Free heme regulates placenta growth factor through NRF2-antioxidant response signaling

Free radical biology & medicine, 2019-11, Vol.143, p.300-308

2019

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LEF1 isoforms regulate cellular senescence and aging

Aging cell, 2023-12, Vol.22 (12), p.e14024-n/a

2023

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Nrf2 deficiency in mice attenuates erythropoietic stress-related macrophage hypercellularity

Experimental hematology, 2020-04, Vol.84, p.19-28.e4

2020

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PARP1 rs1805407 Increases Sensitivity to PARP1 Inhibitors in Cancer Cells Suggesting an Improved Therapeutic Strategy

Scientific reports, 2019-03, Vol.9 (1), p.3309-3309, Article 3309

2019

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Cardiac expression of HMOX1 and PGF in sickle cell mice and haem‐treated wild type mice dominates organ expression profiles via Nrf2 (Nfe2l2)

British journal of haematology, 2019-12, Vol.187 (5), p.666-675

2019

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Monoubiquitinated Histone H2A Destabilizes Photolesion-containing Nucleosomes with Concomitant Release of UV-damaged DNA-binding Protein E3 Ligase

The Journal of biological chemistry, 2012-04, Vol.287 (15), p.12036-12049

2012

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The DDB1-CUL4ADDB2 ubiquitin ligase is deficient in xeroderma pigmentosum group E and targets histone H2A at UV-damaged DNA sites

Proceedings of the National Academy of Sciences - PNAS, 2006-02, Vol.103 (8), p.2588-2593

2006

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High frequencies of Minos transposon mobilization are obtained in insects by using in vitro synthesized mRNA as a source of transposase

Nucleic acids research, 2002-08, Vol.30 (15), p.3333-3340

2002

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The$DDB1-CUL4A^{DDB2}$Ubiquitin Ligase Is Deficient in Xeroderma Pigmentosum Group E and Targets Histone H2A at UV-Damaged DNA Sites

Proceedings of the National Academy of Sciences - PNAS, 2006-02, Vol.103 (8), p.2588-2593

2006

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Macrophage Hypercellularity Accompanies Erythroid Hyperplasia in Sickle Cell Mice and during Recovery from Blood Loss in Wild Type Mice

Blood, 2019-11, Vol.134 (Supplement_1), p.3528-3528

2019

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Free Heme Induces a Heme Importer, Heme Catabolism and an Angiogenic Factor in Multiple Organs in Mice: Implications for Organ-Specific Response to Intravascular Hemolysis

Blood, 2017-12, Vol.130, p.3468-3468

2017

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Heterogeneity in Multi-Organ Expression of HO-1 and PlGF in Sickle Mice Mimic Exposure of Non-Sickle Mice to Extracellular Heme Via Nrf2-Dependent Pathways

Blood, 2018-11, Vol.132 (Supplement 1), p.2392-2392

2018

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Nrf2 Null Mice Are Deficient in CD169+ Macrophages, Associated with Impaired Erythroid Response and Delayed Recovery from Acute Blood Loss

Blood, 2019-11, Vol.134 (Supplement_1), p.1038-1038

2019

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Heme Regulates the Expression in Erythroblasts of Placenta Growth Factor, a Contributor to Pulmonary Hypertension in Sickle Cell Disease, through the Oxidant Response Transcription Factor NRF2

Blood, 2017-12, Vol.130, p.3496-3496

2017

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Influence of age on wound healing and fibrosis: Inflammation, Wound Repair and Fibrosis

The Journal of pathology, 2013, Vol.229 (2), p.310-322

2013

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The Worst Things in Life are Free: The Role of Free Heme in Sickle Cell Disease

Global methylation patterns in idiopathic pulmonary fibrosis

Aging Mesenchymal Stem Cells Fail to Protect Because of Impaired Migration and Antiinflammatory Response

Influence of age on wound healing and fibrosis

Early events marking lung fibroblast transition to profibrotic state in idiopathic pulmonary fibrosis

Heme Induces IL-6 and Cardiac Hypertrophy Genes Transcripts in Sickle Cell Mice

The Cullin 4B-Based UV-Damaged DNA-Binding Protein Ligase Binds to UV-Damaged Chromatin and Ubiquitinates Histone H2A

Expression of regulatory platelet microRNAs in patients with sickle cell disease

Modified mesenchymal stem cells using miRNA transduction alter lung injury in a bleomycin model

The DNA transposon Minos as a tool for transgenesis and functional genomic analysis in vertebrates and invertebrates

Free heme regulates placenta growth factor through NRF2-antioxidant response signaling

LEF1 isoforms regulate cellular senescence and aging

Nrf2 deficiency in mice attenuates erythropoietic stress-related macrophage hypercellularity

PARP1 rs1805407 Increases Sensitivity to PARP1 Inhibitors in Cancer Cells Suggesting an Improved Therapeutic Strategy

Cardiac expression of HMOX1 and PGF in sickle cell mice and haem‐treated wild type mice dominates organ expression profiles via Nrf2 (Nfe2l2)

Monoubiquitinated Histone H2A Destabilizes Photolesion-containing Nucleosomes with Concomitant Release of UV-damaged DNA-binding Protein E3 Ligase

The DDB1-CUL4ADDB2 ubiquitin ligase is deficient in xeroderma pigmentosum group E and targets histone H2A at UV-damaged DNA sites

High frequencies of Minos transposon mobilization are obtained in insects by using in vitro synthesized mRNA as a source of transposase

The$DDB1-CUL4A^{DDB2}$Ubiquitin Ligase Is Deficient in Xeroderma Pigmentosum Group E and Targets Histone H2A at UV-Damaged DNA Sites

Macrophage Hypercellularity Accompanies Erythroid Hyperplasia in Sickle Cell Mice and during Recovery from Blood Loss in Wild Type Mice

Free Heme Induces a Heme Importer, Heme Catabolism and an Angiogenic Factor in Multiple Organs in Mice: Implications for Organ-Specific Response to Intravascular Hemolysis

Heterogeneity in Multi-Organ Expression of HO-1 and PlGF in Sickle Mice Mimic Exposure of Non-Sickle Mice to Extracellular Heme Via Nrf2-Dependent Pathways

Nrf2 Null Mice Are Deficient in CD169+ Macrophages, Associated with Impaired Erythroid Response and Delayed Recovery from Acute Blood Loss

Heme Regulates the Expression in Erythroblasts of Placenta Growth Factor, a Contributor to Pulmonary Hypertension in Sickle Cell Disease, through the Oxidant Response Transcription Factor NRF2

Influence of age on wound healing and fibrosis: Inflammation, Wound Repair and Fibrosis

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