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Targeted silencing of elongation factor 2 kinase suppresses growth and sensitizes tumors to doxorubicin in an orthotopic model of breast cancer

PloS one, 2012-07, Vol.7 (7), p.e41171-e41171

2012

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Arrestin-3 scaffolding of the JNK3 cascade suggests a mechanism for signal amplification

Proceedings of the National Academy of Sciences - PNAS, 2019-01, Vol.116 (3), p.810-815

2019

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NO-releasing STAT3 inhibitors suppress BRAF-mutant melanoma growth

European journal of medicinal chemistry, 2020-01, Vol.186, p.111885-111885, Article 111885

2020

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Rapid characterization of spike variants via mammalian cell surface display

Molecular cell, 2021-12, Vol.81 (24), p.5099-5111.e8

2021

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Local destabilization, rigid body, and fuzzy docking facilitate the phosphorylation of the transcription factor Ets-1 by the mitogen-activated protein kinase ERK2

Proceedings of the National Academy of Sciences - PNAS, 2017-08, Vol.114 (31), p.E6287-E6296

2017

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Short Arrestin-3-Derived Peptides Activate JNK3 in Cells

International journal of molecular sciences, 2022-08, Vol.23 (15), p.8679

2022

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Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding

Nature communications, 2018-02, Vol.9 (1), p.1-9, Article 512

2018

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Multiplexing the Quantitation of MAP Kinase Activities Using Differential Sensing

Journal of the American Chemical Society, 2022-03, Vol.144 (9), p.4017-4025

2022

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JNK3 Enzyme Binding to Arrestin-3 Differentially Affects the Recruitment of Upstream Mitogen-activated Protein (MAP) Kinase Kinases

The Journal of biological chemistry, 2013-10, Vol.288 (40), p.28535-28547

2013

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In-Situ Generation of Differential Sensors that Fingerprint Kinases and the Cellular Response to Their Expression

Journal of the American Chemical Society, 2013-10, Vol.135 (39), p.14814-14820

2013

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Novel quinoline incorporating 1,2,4-triazole/oxime hybrids: Synthesis, molecular docking, anti-inflammatory, COX inhibition, ulceroginicity and histopathological investigations

Bioorganic chemistry, 2017-12, Vol.75, p.242-259

2017

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Arrestin-3 Binds c-Jun N-terminal Kinase 1 (JNK1) and JNK2 and Facilitates the Activation of These Ubiquitous JNK Isoforms in Cells via Scaffolding

The Journal of biological chemistry, 2013-12, Vol.288 (52), p.37332-37342

2013

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Modulating multi-functional ERK complexes by covalent targeting of a recruitment site in vivo

Nature communications, 2019-11, Vol.10 (1), p.5232-15, Article 5232

2019

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Differential Sensing of MAP Kinases Using SOX-Peptides

Angewandte Chemie International Edition, 2014-12, Vol.53 (51), p.14064-14068

International ed. in English, 2014

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Peptide mini-scaffold facilitates JNK3 activation in cells

Scientific reports, 2016-02, Vol.6 (1), p.21025-21025, Article 21025

2016

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Nonvisual Arrestins Function as Simple Scaffolds Assembling the MKK4–JNK3α2 Signaling Complex

Biochemistry (Easton), 2011-12, Vol.50 (48), p.10520-10529

2011

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A c-Jun N-terminal kinase inhibitor, JNK-IN-8, sensitizes triple negative breast cancer cells to lapatinib

Oncotarget, 2017-12, Vol.8 (62), p.104894-104912

2017

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Kinetic and Structural Analysis of Two Linkers in the Tautomerase Superfamily: Analysis and Implications

Biochemistry (Easton), 2021-06, Vol.60 (22), p.1776-1786

2021

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193-nm photodissociation of singly and multiply charged peptide anions for acidic proteome characterization

Proteomics (Weinheim), 2011-04, Vol.11 (7), p.1329-1334

2011

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Novel 1-[4-(Aminosulfonyl)phenyl]-1H-1,2,4-triazole derivatives with remarkable selective COX-2 inhibition: Design, synthesis, molecular docking, anti-inflammatory and ulcerogenicity studies

European journal of medicinal chemistry, 2014-08, Vol.83, p.398-408

2014

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A model of a MAPK•substrate complex in an active conformation: a computational and experimental approach

PloS one, 2011-04, Vol.6 (4), p.e18594

2011

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Arrestin-3 interaction with maternal embryonic leucine-zipper kinase

Cellular signalling, 2019-11, Vol.63, p.109366-109366, Article 109366

2019

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Development of 2′-aminospiro [pyrano[3,2–c]quinoline]-3′-carbonitrile derivatives as non-ATP competitive Src kinase inhibitors that suppress breast cancer cell migration and proliferation

Bioorganic chemistry, 2021-11, Vol.116, p.105344-105344, Article 105344

2021

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A Novel Class of Common Docking Domain Inhibitors That Prevent ERK2 Activation and Substrate Phosphorylation

ACS chemical biology, 2019-06, Vol.14 (6), p.1183-1194

2019

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Targeted silencing of elongation factor 2 kinase suppresses growth and sensitizes tumors to doxorubicin in an orthotopic model of breast cancer

Arrestin-3 scaffolding of the JNK3 cascade suggests a mechanism for signal amplification

NO-releasing STAT3 inhibitors suppress BRAF-mutant melanoma growth

Rapid characterization of spike variants via mammalian cell surface display

Local destabilization, rigid body, and fuzzy docking facilitate the phosphorylation of the transcription factor Ets-1 by the mitogen-activated protein kinase ERK2

Identification of a conserved S2 epitope present on spike proteins from all highly pathogenic coronaviruses

Short Arrestin-3-Derived Peptides Activate JNK3 in Cells

Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding

Multiplexing the Quantitation of MAP Kinase Activities Using Differential Sensing

JNK3 Enzyme Binding to Arrestin-3 Differentially Affects the Recruitment of Upstream Mitogen-activated Protein (MAP) Kinase Kinases

In-Situ Generation of Differential Sensors that Fingerprint Kinases and the Cellular Response to Their Expression

Novel quinoline incorporating 1,2,4-triazole/oxime hybrids: Synthesis, molecular docking, anti-inflammatory, COX inhibition, ulceroginicity and histopathological investigations

Arrestin-3 Binds c-Jun N-terminal Kinase 1 (JNK1) and JNK2 and Facilitates the Activation of These Ubiquitous JNK Isoforms in Cells via Scaffolding

Modulating multi-functional ERK complexes by covalent targeting of a recruitment site in vivo

Differential Sensing of MAP Kinases Using SOX-Peptides

Peptide mini-scaffold facilitates JNK3 activation in cells

Nonvisual Arrestins Function as Simple Scaffolds Assembling the MKK4–JNK3α2 Signaling Complex

A c-Jun N-terminal kinase inhibitor, JNK-IN-8, sensitizes triple negative breast cancer cells to lapatinib

Kinetic and Structural Analysis of Two Linkers in the Tautomerase Superfamily: Analysis and Implications

193-nm photodissociation of singly and multiply charged peptide anions for acidic proteome characterization

Novel 1-[4-(Aminosulfonyl)phenyl]-1H-1,2,4-triazole derivatives with remarkable selective COX-2 inhibition: Design, synthesis, molecular docking, anti-inflammatory and ulcerogenicity studies

A model of a MAPK•substrate complex in an active conformation: a computational and experimental approach

Arrestin-3 interaction with maternal embryonic leucine-zipper kinase

Development of 2′-aminospiro [pyrano[3,2–c]quinoline]-3′-carbonitrile derivatives as non-ATP competitive Src kinase inhibitors that suppress breast cancer cell migration and proliferation

A Novel Class of Common Docking Domain Inhibitors That Prevent ERK2 Activation and Substrate Phosphorylation

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