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Pharmacogenomics of severe cutaneous adverse reactions and drug-induced liver injury

Journal of human genetics, 2013-06, Vol.58 (6), p.317-326

2013

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Clinical Profiles of Japanese Patients with Stevens–Johnson Syndrome/Toxic Epidermal Necrolysis Collected by a Nationwide System from 2006 to 2023

Biological and Pharmaceutical Bulletin, 2024/01/01, Vol.47(1), pp.88-97

2024

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HLA‐B1511 is a risk factor for carbamazepine‐induced Stevens‐Johnson syndrome and toxic epidermal necrolysis in Japanese patients

Epilepsia (Copenhagen), 2010-12, Vol.51 (12), p.2461-2465

2010

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Absence of ethnic differences in the pharmacokinetics of moxifloxacin, simvastatin, and meloxicam among three East Asian populations and Caucasians

British journal of clinical pharmacology, 2016-06, Vol.81 (6), p.1078-1090

2016

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Irinotecan pharmacokinetics/pharmacodynamics and UGT1A genetic polymorphisms in Japanese: roles of UGT1A16 and 28

Pharmacogenetics and genomics, 2007-07, Vol.17 (7), p.497-504

2007

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The risk of cutaneous adverse reactions among patients with the HLA-A 31:01 allele who are given carbamazepine, oxcarbazepine or eslicarbazepine: a perspective review

Therapeutic Advances in Drug Safety, 2013-12, Vol.4 (6), p.246-253

2013

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Pharmacokinetics of Gemcitabine in Japanese Cancer Patients: The Impact of a Cytidine Deaminase Polymorphism

Journal of clinical oncology, 2007-01, Vol.25 (1), p.32-42

2007

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Development of a Rapid and Inexpensive Assay for Detecting a Surrogate Genetic Polymorphism of HLA-B58:01: A Partially Predictive but Useful Biomarker for Allopurinol-related Stevens-Johnson Syndrome/toxic Epidermal Necrolysis in Japanese

DRUG METABOLISM AND PHARMACOKINETICS, 2012, Vol.27 (4), p.447-450

2012

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Drugs causing severe ocular surface involvements in Japanese patients with Stevens–Johnson syndrome/toxic epidermal necrolysis

Allergology international, 2015-10, Vol.64 (4), p.379-381

2015

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Racial variability in haplotype frequencies of UGT1A1 and glucuronidation activity of a novel single nucleotide polymorphism 686C> T (P229L) found in an African-American

Drug metabolism and disposition, 2005-03, Vol.33 (3), p.458

2005

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Prediction of Severe Adverse Drug Reactions Using Pharmacogenetic Biomarkers

DRUG METABOLISM AND PHARMACOKINETICS, 2010-01, Vol.25 (2), p.122-133

2010

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Identification of a candidate single-nucleotide polymorphism related to chemotherapeutic response through a combination of knowledge-based algorithm and hypothesis-free genomic data

Journal of bioscience and bioengineering, 2013-12, Vol.116 (6), p.768-773

2013

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Substrate-dependent functional alterations of seven CYP2C9 variants found in Japanese subjects

Drug metabolism and disposition, 2009-09, Vol.37 (9), p.1895

2009

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Construction of possible integrated predictive index based on EGFR and ANXA3 polymorphisms for chemotherapy response in fluoropyrimidine-treated Japanese gastric cancer patients using a bioinformatic method

BMC cancer, 2015-10, Vol.15 (1), p.718-718, Article 718

2015

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Identification of a Predictive Biomarker for Hematologic Toxicities of Gemcitabine

Journal of clinical oncology, 2009-05, Vol.27 (13), p.2261-2268

2009

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Genetic Polymorphisms and Haplotypes of POR, Encoding Cytochrome P450 Oxidoreductase, in a Japanese Population

DRUG METABOLISM AND PHARMACOKINETICS, 2011-01, Vol.26 (1), p.107-116

2011

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Additive effects of drug transporter genetic polymorphisms on irinotecan pharmacokinetics/pharmacodynamics in Japanese cancer patients

Cancer chemotherapy and pharmacology, 2010-05, Vol.66 (1), p.95-105

2010

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Survival Prediction for Pancreatic Cancer Patients Receiving Gemcitabine Treatment

Molecular & cellular proteomics, 2010-04, Vol.9 (4), p.695-704

2010

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Ethnic Differences of two Non-synonymous Single Nucleotide Polymorphisms in CDA Gene

DRUG METABOLISM AND PHARMACOKINETICS, 2009-01, Vol.24 (6), p.553-556

2009

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Genetic variations and haplotype structures of the DPYD gene encoding dihydropyrimidine dehydrogenase in Japanese and their ethnic differences

Journal of human genetics, 2007-10, Vol.52 (10), p.804-819

2007

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Utilization of Genomic Biomarkers for Post-marketing Safety of Drugs

YAKUGAKU ZASSHI, 2015/05/01, Vol.135(5), pp.671-679

Kaniwa, Nahoko

2015

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Close association of UGT1A9 IVS1+399C>T with UGT1A128, 6, or 60 haplotype and its apparent influence on 7-ethyl-10-hydroxycamptothecin (SN-38) glucuronidation in Japanese

Drug metabolism and disposition, 2009-02, Vol.37 (2), p.272

2009

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Functional characterization of human UDP-glucuronosyltransferase 1A9 variant, D256N, found in Japanese cancer patients

The Journal of pharmacology and experimental therapeutics, 2003-08, Vol.306 (2), p.688

2003

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Genetic Variation and Haplotype Structure of the ABC Transporter Gene ABCG2 in a Japanese Population

DRUG METABOLISM AND PHARMACOKINETICS, 2006-01, Vol.21 (2), p.109-121

2006

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Pharmacogenomics of severe cutaneous adverse reactions and drug-induced liver injury

Clinical Profiles of Japanese Patients with Stevens–Johnson Syndrome/Toxic Epidermal Necrolysis Collected by a Nationwide System from 2006 to 2023

HLA‐B1511 is a risk factor for carbamazepine‐induced Stevens‐Johnson syndrome and toxic epidermal necrolysis in Japanese patients

Absence of ethnic differences in the pharmacokinetics of moxifloxacin, simvastatin, and meloxicam among three East Asian populations and Caucasians

Irinotecan pharmacokinetics/pharmacodynamics and UGT1A genetic polymorphisms in Japanese: roles of UGT1A16 and 28

The risk of cutaneous adverse reactions among patients with the HLA-A 31:01 allele who are given carbamazepine, oxcarbazepine or eslicarbazepine: a perspective review

Pharmacokinetics of Gemcitabine in Japanese Cancer Patients: The Impact of a Cytidine Deaminase Polymorphism

Development of a Rapid and Inexpensive Assay for Detecting a Surrogate Genetic Polymorphism of HLA-B58:01: A Partially Predictive but Useful Biomarker for Allopurinol-related Stevens-Johnson Syndrome/toxic Epidermal Necrolysis in Japanese

Drugs causing severe ocular surface involvements in Japanese patients with Stevens–Johnson syndrome/toxic epidermal necrolysis

Racial variability in haplotype frequencies of UGT1A1 and glucuronidation activity of a novel single nucleotide polymorphism 686C> T (P229L) found in an African-American

Prediction of Severe Adverse Drug Reactions Using Pharmacogenetic Biomarkers

Identification of a candidate single-nucleotide polymorphism related to chemotherapeutic response through a combination of knowledge-based algorithm and hypothesis-free genomic data

Substrate-dependent functional alterations of seven CYP2C9 variants found in Japanese subjects

Construction of possible integrated predictive index based on EGFR and ANXA3 polymorphisms for chemotherapy response in fluoropyrimidine-treated Japanese gastric cancer patients using a bioinformatic method

Identification of a Predictive Biomarker for Hematologic Toxicities of Gemcitabine

Genetic Polymorphisms and Haplotypes of POR, Encoding Cytochrome P450 Oxidoreductase, in a Japanese Population

Additive effects of drug transporter genetic polymorphisms on irinotecan pharmacokinetics/pharmacodynamics in Japanese cancer patients

Application of a combination of a knowledge-based algorithm and 2-stage screening to hypothesis-free genomic data on irinotecan-treated patients for identification of a candidate single nucleotide polymorphism related to an adverse effect

Survival Prediction for Pancreatic Cancer Patients Receiving Gemcitabine Treatment

Ethnic Differences of two Non-synonymous Single Nucleotide Polymorphisms in CDA Gene

Genetic variations and haplotype structures of the DPYD gene encoding dihydropyrimidine dehydrogenase in Japanese and their ethnic differences

Utilization of Genomic Biomarkers for Post-marketing Safety of Drugs

Close association of UGT1A9 IVS1+399C>T with UGT1A128, 6, or 60 haplotype and its apparent influence on 7-ethyl-10-hydroxycamptothecin (SN-38) glucuronidation in Japanese

Functional characterization of human UDP-glucuronosyltransferase 1A9 variant, D256N, found in Japanese cancer patients

Genetic Variation and Haplotype Structure of the ABC Transporter Gene ABCG2 in a Japanese Population

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