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From ions to insulin

eLife, 2017-03, Vol.6

Kanelis, Voula

2017

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Isotope labeling strategies for the study of high-molecular-weight proteins by solution NMR spectroscopy

Nature protocols, 2006-07, Vol.1 (2), p.749-754

2006

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HNH proteins are a widespread component of phage DNA packaging machines

Proceedings of the National Academy of Sciences - PNAS, 2014-04, Vol.111 (16), p.6022-6027

2014

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phage λ major tail protein structure reveals a common evolution for long-tailed phages and the type VI bacterial secretion system

Proceedings of the National Academy of Sciences - PNAS, 2009-03, Vol.106 (11), p.4160-4165

2009

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Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein

PLoS pathogens, 2017-06, Vol.13 (6), p.e1006394-e1006394

2017

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Regulation of Nedd4-2 self-ubiquitination and stability by a PY motif located within its HECT-domain

Biochemical journal, 2008-10, Vol.415 (1), p.155-163

2008

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Probing Slow Dynamics in High Molecular Weight Proteins by Methyl-TROSY NMR Spectroscopy: Application to a 723-Residue Enzyme

Journal of the American Chemical Society, 2004-03, Vol.126 (12), p.3964-3973

2004

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Solution structure of a Nedd4 WW domain-ENaC peptide complex

Nature structural & molecular biology, 2001-05, Vol.8 (5), p.407-412

2001

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Trafficking and cell surface stability of ENaC

American journal of physiology. Renal physiology, 2001-09, Vol.281 (3), p.F391-F399

2001

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Intrinsically disordered regions in Katp channels are allosterically coupled

Biophysical journal, 2024-02, Vol.123 (3), p.169a-169a

2024

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Structural Determinants for High-Affinity Binding in a Nedd4 WW3 ∗ Domain-Comm PY Motif Complex

Structure (London), 2006-03, Vol.14 (3), p.543-553

2006

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Regulation of the epithelial Na+ channel by Nedd4 and ubiquitination

Kidney international, 2000-03, Vol.57 (3), p.809-815

2000

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Affinity and Specificity of Interactions between Nedd4 Isoforms and the Epithelial Na+ Channel

The Journal of biological chemistry, 2003-05, Vol.278 (22), p.20019-20028

2003

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Structure of Ycf1p reveals the transmembrane domain TMD0 and the regulatory region of ABCC transporters

Proceedings of the National Academy of Sciences - PNAS, 2021-05, Vol.118 (21), p.1-9

2021

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Editorial for the special issue “A Celebration of Women in Biophysical Chemistry”

Biophysical chemistry, 2023-01, Vol.292, p.106929-106929, Article 106929

2023

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Multidimensional NMR Methods for Protein Structure Determination

IUBMB life, 2001-12, Vol.52 (6), p.291-302

2001

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Intrinsically disordered regions regulate the activities of ATP binding cassette transporters

Biochimica et biophysica acta. Biomembranes, 2020-06, Vol.1862 (6), p.183202-183202, Article 183202

2020

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Biochemical studies highlight determinants for metal selectivity in the Escherichia coli periplasmic solute binding protein NikA

Metallomics, 2022-11, Vol.14 (11)

2022

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The protein gp74 from the bacteriophage HK97 functions as a HNH endonuclease

Protein science, 2012-06, Vol.21 (6), p.809-818

2012

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Hyperinsulinism-Causing Mutations Cause Multiple Molecular Defects in SUR1 NBD1

Biochemistry (Easton), 2017-05, Vol.56 (18), p.2400-2416

2017

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HK97 gp74 Possesses an α-Helical Insertion in the ββα Fold That Affects Its Metal Binding, cos Site Digestion, and In Vivo Activities

Journal of bacteriology, 2020-03, Vol.202 (8)

2020

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Phosphorylation Alters the Residual Structure and Interactions of the Regulatory L1 Linker Connecting NBD1 to the Membrane-Bound Domain in SUR2B

Biochemistry (Easton), 2018-11, Vol.57 (44), p.6278-6292

2018

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Structure‐based design of a photoswitchable affibody scaffold

Protein science, 2021-12, Vol.30 (12), p.2359-2372

2021

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Strategies for purification of the bacteriophage HK97 small and large terminase subunits that yield pure and homogeneous samples that are functional

Protein expression and purification, 2019-08, Vol.160, p.45-55

2019

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CFTR regulatory region interacts with NBD1 predominantly via multiple transient helices

Nature structural & molecular biology, 2007-08, Vol.14 (8), p.738-745

2007

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From ions to insulin

Isotope labeling strategies for the study of high-molecular-weight proteins by solution NMR spectroscopy

HNH proteins are a widespread component of phage DNA packaging machines

phage λ major tail protein structure reveals a common evolution for long-tailed phages and the type VI bacterial secretion system

Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein

Regulation of Nedd4-2 self-ubiquitination and stability by a PY motif located within its HECT-domain

Probing Slow Dynamics in High Molecular Weight Proteins by Methyl-TROSY NMR Spectroscopy: Application to a 723-Residue Enzyme

Solution structure of a Nedd4 WW domain-ENaC peptide complex

Trafficking and cell surface stability of ENaC

Intrinsically disordered regions in Katp channels are allosterically coupled

Structural Determinants for High-Affinity Binding in a Nedd4 WW3 ∗ Domain-Comm PY Motif Complex

Regulation of the epithelial Na+ channel by Nedd4 and ubiquitination

Affinity and Specificity of Interactions between Nedd4 Isoforms and the Epithelial Na+ Channel

Structure of Ycf1p reveals the transmembrane domain TMD0 and the regulatory region of ABCC transporters

Editorial for the special issue “A Celebration of Women in Biophysical Chemistry”

Multidimensional NMR Methods for Protein Structure Determination

Intrinsically disordered regions regulate the activities of ATP binding cassette transporters

Biochemical studies highlight determinants for metal selectivity in the Escherichia coli periplasmic solute binding protein NikA

The protein gp74 from the bacteriophage HK97 functions as a HNH endonuclease

Hyperinsulinism-Causing Mutations Cause Multiple Molecular Defects in SUR1 NBD1

HK97 gp74 Possesses an α-Helical Insertion in the ββα Fold That Affects Its Metal Binding, cos Site Digestion, and In Vivo Activities

Phosphorylation Alters the Residual Structure and Interactions of the Regulatory L1 Linker Connecting NBD1 to the Membrane-Bound Domain in SUR2B

Structure‐based design of a photoswitchable affibody scaffold

Strategies for purification of the bacteriophage HK97 small and large terminase subunits that yield pure and homogeneous samples that are functional

CFTR regulatory region interacts with NBD1 predominantly via multiple transient helices

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