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PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells

Nature structural & molecular biology, 2013-11, Vol.20 (11), p.1258-1264

2013

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Interactions between JARID2 and Noncoding RNAs Regulate PRC2 Recruitment to Chromatin

Molecular cell, 2014-01, Vol.53 (2), p.290-300

2014

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Nascent RNA interaction keeps PRC2 activity poised and in check

Genes & development, 2014-09, Vol.28 (18), p.1983-1988

2014

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Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA

Genes & development, 2010-12, Vol.24 (23), p.2615-2620

2010

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Allosteric Activation Dictates PRC2 Activity Independent of Its Recruitment to Chromatin

Molecular cell, 2018-05, Vol.70 (3), p.422-434.e6

2018

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Epigenetics Analysis and Integrated Analysis of Multiomics Data, Including Epigenetic Data, Using Artificial Intelligence in the Era of Precision Medicine

Biomolecules (Basel, Switzerland), 2019-12, Vol.10 (1), p.62

2019

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Application of Artificial Intelligence Technology in Oncology: Towards the Establishment of Precision Medicine

Cancers, 2020-11, Vol.12 (12), p.3532

2020

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Downregulation of METTL6 mitigates cell progression, migration, invasion and adhesion in hepatocellular carcinoma by inhibiting cell adhesion molecules

International journal of oncology, 2022-01, Vol.60 (1), p.1, Article 4

2022

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Jarid2 Is Implicated in the Initial Xist-Induced Targeting of PRC2 to the Inactive X Chromosome

Molecular cell, 2014-01, Vol.53 (2), p.301-316

2014

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Detection of Cardiac Structural Abnormalities in Fetal Ultrasound Videos Using Deep Learning

Applied sciences, 2021-01, Vol.11 (1), p.371

2021

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Application of non-negative matrix factorization in oncology: one approach for establishing precision medicine

Briefings in bioinformatics, 2022-07, Vol.23 (4)

2022

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Replication stress triggers microsatellite destabilization and hypermutation leading to clonal expansion in vitro

Nature communications, 2019-09, Vol.10 (1), p.3925-13, Article 3925

2019

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Integrative analysis reveals early epigenetic alterations in high-grade serous ovarian carcinomas

Experimental and Molecular Medicine, 2023, 55(0), , pp.2205-2219

2023

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Analysis of super-enhancer using machine learning and its application to medical biology

Briefings in bioinformatics, 2023-05, Vol.24 (3)

2023

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Towards Clinical Application of Artificial Intelligence in Ultrasound Imaging

Biomedicines, 2021-06, Vol.9 (7), p.720

2021

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Advances in cancer DNA methylation analysis with methPLIER: use of non-negative matrix factorization and knowledge-based constraints to enhance biological interpretability

Experimental and Molecular Medicine, 2024, 56(0), , pp.646-655

2024

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Integrated Analysis of Whole Genome and Epigenome Data Using Machine Learning Technology: Toward the Establishment of Precision Oncology

Frontiers in oncology, 2021-05, Vol.11, p.666937-666937

2021

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Image Segmentation of the Ventricular Septum in Fetal Cardiac Ultrasound Videos Based on Deep Learning Using Time-Series Information

Biomolecules (Basel, Switzerland), 2020-11, Vol.10 (11), p.1526

2020

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Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease

Nature, 2006-12, Vol.444 (7121), p.953-956

2006

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The multifunctional protein p54nrb/PSF recruits the exonuclease XRN2 to facilitate pre-mRNA 3' processing and transcription termination

Genes & development, 2007-07, Vol.21 (14), p.1779-1789

2007

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Uncovering Prognosis-Related Genes and Pathways by Multi-Omics Analysis in Lung Cancer

Biomolecules (Basel, Switzerland), 2020-03, Vol.10 (4), p.524

2020

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Identification of the mutation signature of the cancer genome caused by irradiation

Radiotherapy and oncology, 2021-02, Vol.155, p.10-16

2021

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Predicting Deep Learning Based Multi-Omics Parallel Integration Survival Subtypes in Lung Cancer Using Reverse Phase Protein Array Data

Biomolecules (Basel, Switzerland), 2020-10, Vol.10 (10), p.1460

2020

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Multi-omics and clustering analyses reveal the mechanisms underlying unmet needs for patients with lung adenocarcinoma and identify potential therapeutic targets

Molecular cancer, 2024-09, Vol.23 (1), p.182-9, Article 182

2024

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PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells

Interactions between JARID2 and Noncoding RNAs Regulate PRC2 Recruitment to Chromatin

Nascent RNA interaction keeps PRC2 activity poised and in check

Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA

Allosteric Activation Dictates PRC2 Activity Independent of Its Recruitment to Chromatin

Epigenetics Analysis and Integrated Analysis of Multiomics Data, Including Epigenetic Data, Using Artificial Intelligence in the Era of Precision Medicine

Application of Artificial Intelligence Technology in Oncology: Towards the Establishment of Precision Medicine

Downregulation of METTL6 mitigates cell progression, migration, invasion and adhesion in hepatocellular carcinoma by inhibiting cell adhesion molecules

Jarid2 Is Implicated in the Initial Xist-Induced Targeting of PRC2 to the Inactive X Chromosome

Detection of Cardiac Structural Abnormalities in Fetal Ultrasound Videos Using Deep Learning

Application of non-negative matrix factorization in oncology: one approach for establishing precision medicine

Replication stress triggers microsatellite destabilization and hypermutation leading to clonal expansion in vitro

Integrative analysis reveals early epigenetic alterations in high-grade serous ovarian carcinomas

Analysis of super-enhancer using machine learning and its application to medical biology

Towards Clinical Application of Artificial Intelligence in Ultrasound Imaging

Advances in cancer DNA methylation analysis with methPLIER: use of non-negative matrix factorization and knowledge-based constraints to enhance biological interpretability

Integrated Analysis of Whole Genome and Epigenome Data Using Machine Learning Technology: Toward the Establishment of Precision Oncology

Image Segmentation of the Ventricular Septum in Fetal Cardiac Ultrasound Videos Based on Deep Learning Using Time-Series Information

Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease

The multifunctional protein p54nrb/PSF recruits the exonuclease XRN2 to facilitate pre-mRNA 3' processing and transcription termination

Uncovering Prognosis-Related Genes and Pathways by Multi-Omics Analysis in Lung Cancer

Identification of the mutation signature of the cancer genome caused by irradiation

Predicting Deep Learning Based Multi-Omics Parallel Integration Survival Subtypes in Lung Cancer Using Reverse Phase Protein Array Data

Multi-omics and clustering analyses reveal the mechanisms underlying unmet needs for patients with lung adenocarcinoma and identify potential therapeutic targets

Mechanism of ERBB2 gene overexpression by the formation of super-enhancer with genomic structural abnormalities in lung adenocarcinoma without clinically actionable genetic alterations

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