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Role of PINK1 Binding to the TOM Complex and Alternate Intracellular Membranes in Recruitment and Activation of the E3 Ligase Parkin

Developmental cell, 2012-02, Vol.22 (2), p.320-333

2012

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The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

Nature (London), 2015-08, Vol.524 (7565), p.309-314

2015

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PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity

The Journal of cell biology, 2014-04, Vol.205 (2), p.143-153

2014

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Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL

The Journal of cell biology, 2010-11, Vol.191 (5), p.933-942

2010

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p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both

Autophagy, 2010-11, Vol.6 (8), p.1090-1106

2010

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PINK1 and Parkin Flag Miro to Direct Mitochondrial Traffic

Cell, 2011-11, Vol.147 (4), p.721-723

2011

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Preparation of proteins and peptides for mass spectrometry analysis in a bottom-up proteomics workflow

Current protocols in molecular biology (Print), 2009-10, Vol.Chapter 10 (1), p.Unit10.25-Unit10.25

2009

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Type I Keratin 17 Protein Is Phosphorylated on Serine 44 by p90 Ribosomal Protein S6 Kinase 1 (RSK1) in a Growth- and Stress-dependent Fashion

The Journal of biological chemistry, 2011-12, Vol.286 (49), p.42403-42413

2011

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Highly divergent mitochondrial ATP synthase complexes in Tetrahymena thermophila

PLoS biology, 2010-07, Vol.8 (7), p.e1000418

2010

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Modulation of mitochondrial proteome and improved mitochondrial function by biventricular pacing of dyssynchronous failing hearts

Circulation. Cardiovascular genetics, 2010-02, Vol.3 (1), p.78-87

2010

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High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy

Nature (London), 2013-12, Vol.504 (7479), p.291-295

2013

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Post-translational modifications of ATP synthase in the heart: biology and function

Journal of bioenergetics and biomembranes, 2009-04, Vol.41 (2), p.145-150

2009

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SARM1 is responsible for calpain-dependent dendrite degeneration in mouse hippocampal neurons

The Journal of biological chemistry, 2024-02, Vol.300 (2), p.105630-105630, Article 105630

2024

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Polyubiquitin-sensor proteins reveal localization and linkage-type dependence of cellular ubiquitin signaling

Nature methods, 2012-03, Vol.9 (3), p.303-309

2012

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Discovery of DNL343: A Potent, Selective, and Brain-Penetrant eIF2B Activator Designed for the Treatment of Neurodegenerative Diseases

Journal of medicinal chemistry, 2024-04, Vol.67 (7), p.5758-5782

2024

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Site-Mapping of In Vitro S-nitrosation in Cardiac Mitochondria: Implications for Cardioprotection

Molecular & cellular proteomics, 2011-03, Vol.10 (3), p.M110.004721-M110.004721, Article M110.004721

2011

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Mitochondrial fission and fusion and their roles in the heart

Journal of molecular medicine (Berlin, Germany), 2010-10, Vol.88 (10), p.971-979

2010

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Phosphorylation of the F1Fo ATP Synthase β Subunit: Functional and Structural Consequences Assessed in a Model System

Circulation research, 2010-02, Vol.106 (3), p.504-513

2010

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Proteomic Analysis of Pharmacological Preconditioning: Novel Protein Targets Converge to Mitochondrial Metabolism Pathways

Circulation research, 2006-09, Vol.99 (7), p.706-714

2006

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Subfractionation of heart tissue: the "in sequence" myofilament protein extraction of myocardial tissue

Methods in molecular biology (Clifton, N.J.), 2007, Vol.357, p.87

2007

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Optimization of paper bridge loading for 2-DE analysis in the basic pH region: Application to the mitochondrial subproteome

Proteomics (Weinheim), 2006-11, Vol.6 (21), p.5683-5687

2006

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Mitochondrial fission and fusion and their roles in the heart : The role of mitochondrial fission, fussion and biogenesis in cardiovascular diseases

Journal of molecular medicine (Berlin, Germany), 2010, Vol.88 (10), p.971-979

2010

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Phosphorylation of the F 1 F o ATP Synthase β Subunit: Functional and Structural Consequences Assessed in a Model System

Circulation research, 2010-02, Vol.106 (3), p.504-513

2010

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Role of PINK1 Binding to the TOM Complex and Alternate Intracellular Membranes in Recruitment and Activation of the E3 Ligase Parkin

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity

Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL

p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both

PINK1 and Parkin Flag Miro to Direct Mitochondrial Traffic

Preparation of proteins and peptides for mass spectrometry analysis in a bottom-up proteomics workflow

Type I Keratin 17 Protein Is Phosphorylated on Serine 44 by p90 Ribosomal Protein S6 Kinase 1 (RSK1) in a Growth- and Stress-dependent Fashion

Highly divergent mitochondrial ATP synthase complexes in Tetrahymena thermophila

Modulation of mitochondrial proteome and improved mitochondrial function by biventricular pacing of dyssynchronous failing hearts

High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy

Post-translational modifications of ATP synthase in the heart: biology and function

SARM1 is responsible for calpain-dependent dendrite degeneration in mouse hippocampal neurons

Polyubiquitin-sensor proteins reveal localization and linkage-type dependence of cellular ubiquitin signaling

Discovery of DNL343: A Potent, Selective, and Brain-Penetrant eIF2B Activator Designed for the Treatment of Neurodegenerative Diseases

Discovery of Potent and Selective Dual Leucine Zipper Kinase/Leucine Zipper-Bearing Kinase Inhibitors with Neuroprotective Properties in In Vitro and In Vivo Models of Amyotrophic Lateral Sclerosis

Site-Mapping of In Vitro S-nitrosation in Cardiac Mitochondria: Implications for Cardioprotection

Mitochondrial fission and fusion and their roles in the heart

Phosphorylation of the F1Fo ATP Synthase β Subunit: Functional and Structural Consequences Assessed in a Model System

Proteomic Analysis of Pharmacological Preconditioning: Novel Protein Targets Converge to Mitochondrial Metabolism Pathways

Subfractionation of heart tissue: the "in sequence" myofilament protein extraction of myocardial tissue

Optimization of paper bridge loading for 2-DE analysis in the basic pH region: Application to the mitochondrial subproteome

DNL343 is an investigational CNS penetrant eukaryotic initiation factor 2B activator that prevents and reverses the effects of neurodegeneration caused by the integrated stress response

Mitochondrial fission and fusion and their roles in the heart : The role of mitochondrial fission, fussion and biogenesis in cardiovascular diseases

Phosphorylation of the F 1 F o ATP Synthase β Subunit: Functional and Structural Consequences Assessed in a Model System

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