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The Human Cytotoxic T Cell Granule Serine Protease Granzyme H Has Chymotrypsin-like (Chymase) Activity and Is Taken Up into Cytoplasmic Vesicles Reminiscent of Granzyme B-containing Endosomes

The Journal of biological chemistry, 1999-10, Vol.274 (43), p.30468-30473

1999

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Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions

The Journal of experimental medicine, 1992-12, Vol.176 (6), p.1521-1529

1992

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Recombinant Human Granzyme A Binds to Two Putative HLA-Associated Proteins and Cleaves One of them

Proceedings of the National Academy of Sciences - PNAS, 1997-08, Vol.94 (17), p.9285-9290

1997

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Dipeptide Phosphonates as Inhibitors of Dipeptidyl Peptidase IV

Journal of medicinal chemistry, 1994-11, Vol.37 (23), p.3969-3976

1994

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Novel amidine-containing peptidyl phosphonates as irreversible inhibitors for blood coagulation and related serine proteases

Journal of medicinal chemistry, 1994-01, Vol.37 (2), p.226-231

1994

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Synthesis and Evaluation of Diphenyl Phosphonate Esters as Inhibitors of the Trypsin-like Granzymes A and K and Mast Cell Tryptase

Journal of medicinal chemistry, 1998-06, Vol.41 (13), p.2289-2301

1998

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Cutaneous protease activity in the mouse ear vesicant model

Journal of applied toxicology, 2000-12, Vol.20 (S1), p.S177-S182

2000

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Mechanism-Based Isocoumarin Inhibitors for Human Leukocyte Elastase. Effect of the 7-Amino Substituent and 3-Alkoxy Group in 3-Alkoxy-7-amino-4-chloroisocoumarins on Inhibitory Potency

Journal of medicinal chemistry, 1995-02, Vol.38 (3), p.544-552

1995

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Design and evaluation of inhibitors for dipeptidyl peptidase I (Cathepsin C)

Archives of biochemistry and biophysics, 2004-07, Vol.427 (2), p.123-134

2004

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Biotinylated isocoumarins, new inhibitors and reagents for detection, localization, and isolation of serine proteases

Bioconjugate chemistry, 1993-11, Vol.4 (6), p.560-567

1993

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Mechanism-Based Isocoumarin Inhibitors for Blood Coagulation Serine Proteases. Effect of the 7-Substituent in 7-Amino-4-chloro-3-(isothioureidoalkoxy)isocoumarins on Inhibitory and Anticoagulant Potency

Journal of medicinal chemistry, 1994-04, Vol.37 (9), p.1298-1306

1994

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Dipeptidyl peptidase I: importance of progranzyme activation sequences, other dipeptide sequences, and the N-terminal amino group of synthetic substrates for enzyme activity

Archives of biochemistry and biophysics, 2002-07, Vol.403 (2), p.160-170

2002

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Purification and Characterization of Lymphocyte Chymase I, a Granzyme Implicated in Perforin-Mediated Lysis

The Journal of immunology (1950), 1998-05, Vol.160 (10), p.4988-4993

1998

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Substrate and inhibitor studies on proteinase 3

FEBS letters, 1992-02, Vol.297 (1), p.119-123

1992

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Granzymes (lymphocyte serine proteases): characterization with natural and synthetic substrates and inhibitors

Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular Enzymology, 2000-03, Vol.1477 (1), p.307-323

2000

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Mechanism-based isocoumarin inhibitors for trypsin and blood coagulation serine proteases: new anticoagulants

Biochemistry (Easton), 1988-04, Vol.27 (7), p.2547-2557

1988

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Subsite specificities of granzyme M: a study of inhibitors and newly synthesized thiobenzyl ester substrates

Archives of biochemistry and biophysics, 2004-02, Vol.422 (1), p.9-22

2004

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Human and murine cytotoxic T lymphocyte serine proteases: subsite mapping with peptide thioester substrates and inhibition of enzyme activity and cytolysis by isocoumarins

Biochemistry (Easton), 1991-02, Vol.30 (8), p.2217-2227

1991

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Novel anthraquinone inhibitors of human leukocyte elastase and cathepsin G

Journal of medicinal chemistry, 1992-05, Vol.35 (9), p.1597-1605

1992

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Determination of proteinase 3—α1‐antitrypsin complexes in inflammatory fluids

FEBS letters, 1992-12, Vol.314 (2), p.117-121

1992

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Mechanism-based isocoumarin inhibitors for serine proteases: Use of active site structure and substrate specificity in inhibitor design

Journal of cellular biochemistry, 1989-01, Vol.39 (1), p.33-46

1989

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Reactions of [14C]-3,4-Dichloroisocoumarin with Subunits of Pituitary and Spleen Multicatalytic Proteinase Complexes (Proteasomes)

Biochemistry (Easton), 1997-11, Vol.36 (45), p.13946-13953

1997

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Expression and Purification of Enzymatically Active Recombinant Granzyme B in a Baculovirus System

Biochemical and biophysical research communications, 1998-02, Vol.243 (2), p.384-389

1998

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Inhibition of thermolysin and carboxypeptidase A by phosphoramidates

Biochemistry (Easton), 1979-07, Vol.18 (14), p.3032-3038

1979

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Dipeptide vinyl sulfones suitable for intracellular inhibition of dipeptidyl peptidase I

International immunopharmacology, 2001, Vol.1 (1), p.21-32

2001

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The Human Cytotoxic T Cell Granule Serine Protease Granzyme H Has Chymotrypsin-like (Chymase) Activity and Is Taken Up into Cytoplasmic Vesicles Reminiscent of Granzyme B-containing Endosomes

Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions

Recombinant Human Granzyme A Binds to Two Putative HLA-Associated Proteins and Cleaves One of them

Dipeptide Phosphonates as Inhibitors of Dipeptidyl Peptidase IV

Novel amidine-containing peptidyl phosphonates as irreversible inhibitors for blood coagulation and related serine proteases

Synthesis and Evaluation of Diphenyl Phosphonate Esters as Inhibitors of the Trypsin-like Granzymes A and K and Mast Cell Tryptase

Cutaneous protease activity in the mouse ear vesicant model

Mechanism-Based Isocoumarin Inhibitors for Human Leukocyte Elastase. Effect of the 7-Amino Substituent and 3-Alkoxy Group in 3-Alkoxy-7-amino-4-chloroisocoumarins on Inhibitory Potency

Design and evaluation of inhibitors for dipeptidyl peptidase I (Cathepsin C)

Biotinylated isocoumarins, new inhibitors and reagents for detection, localization, and isolation of serine proteases

Mechanism-Based Isocoumarin Inhibitors for Blood Coagulation Serine Proteases. Effect of the 7-Substituent in 7-Amino-4-chloro-3-(isothioureidoalkoxy)isocoumarins on Inhibitory and Anticoagulant Potency

Dipeptidyl peptidase I: importance of progranzyme activation sequences, other dipeptide sequences, and the N-terminal amino group of synthetic substrates for enzyme activity

Purification and Characterization of Lymphocyte Chymase I, a Granzyme Implicated in Perforin-Mediated Lysis

Substrate and inhibitor studies on proteinase 3

Granzymes (lymphocyte serine proteases): characterization with natural and synthetic substrates and inhibitors

Mechanism-based isocoumarin inhibitors for trypsin and blood coagulation serine proteases: new anticoagulants

Subsite specificities of granzyme M: a study of inhibitors and newly synthesized thiobenzyl ester substrates

Human and murine cytotoxic T lymphocyte serine proteases: subsite mapping with peptide thioester substrates and inhibition of enzyme activity and cytolysis by isocoumarins

Novel anthraquinone inhibitors of human leukocyte elastase and cathepsin G

Determination of proteinase 3—α1‐antitrypsin complexes in inflammatory fluids

Mechanism-based isocoumarin inhibitors for serine proteases: Use of active site structure and substrate specificity in inhibitor design

Reactions of [14C]-3,4-Dichloroisocoumarin with Subunits of Pituitary and Spleen Multicatalytic Proteinase Complexes (Proteasomes)

Expression and Purification of Enzymatically Active Recombinant Granzyme B in a Baculovirus System

Inhibition of thermolysin and carboxypeptidase A by phosphoramidates

Dipeptide vinyl sulfones suitable for intracellular inhibition of dipeptidyl peptidase I

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