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Discovery of ODM-201, a new-generation androgen receptor inhibitor targeting resistance mechanisms to androgen signaling-directed prostate cancer therapies

Scientific reports, 2015-07, Vol.5 (1), p.12007-12007, Article 12007

2015

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ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity

Molecular cancer therapeutics, 2019-01, Vol.18 (1), p.28-38

2019

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Adrenals Contribute to Growth of Castration-Resistant VCaP Prostate Cancer Xenografts

The American journal of pathology, 2018-12, Vol.188 (12), p.2890-2901

2018

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Discovery and development of ODM-204: A Novel nonsteroidal compound for the treatment of castration-resistant prostate cancer by blocking the androgen receptor and inhibiting CYP17A1

The Journal of steroid biochemistry and molecular biology, 2019-09, Vol.192, p.105115-105115, Article 105115

2019

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High intratumoral dihydrotestosterone is associated with antiandrogen resistance in VCaP prostate cancer xenografts in castrated mice

iScience, 2022-05, Vol.25 (5), p.104287-104287, Article 104287

2022

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Activation of Hypoxia-Inducible Factor 1α : Posttranscriptional Regulation and Conformational Change by Recruitment of the Arnt Transcription Factor

Proceedings of the National Academy of Sciences - PNAS, 1997-05, Vol.94 (11), p.5667-5672

1997

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Three-dimensional models of cancer for pharmacology and cancer cell biology: Capturing tumor complexity in vitro/ex vivo

Biotechnology journal, 2014-09, Vol.9 (9), p.1115-1128

2014

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Scientific Basis of a Matrix Metalloproteinase-8 Specific Chair-side Test for Monitoring Periodontal and Peri-implant Health and Disease

Annals of the New York Academy of Sciences, 1999-06, Vol.878 (1), p.130-140

1999

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Mutual Transcriptional Interference between RelA and Androgen Receptor

The Journal of biological chemistry, 1996-09, Vol.271 (39), p.24151-24156

1996

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Abstract 674: ODM-201 - New generation androgen receptor inhibitor targeting resistance mechanisms to androgen signalling-directed prostate cancer therapies

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.674-674

2014

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Self-assessed bleeding in monitoring gingival health among adolescents

Community dentistry and oral epidemiology, 1996-04, Vol.24 (2), p.128-132

Kallio, Pekka

1996

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Abstract 3970: Therapeutic targeting of estrogen receptor positive breast cancer with the BET bromodomain inhibitor ODM-207

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.3970-3970

2018

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CYP11A1 inhibition as a therapeutic approach for the treatment of castration resistant prostate cancer

Journal of clinical oncology, 2018-02, Vol.36 (6_suppl), p.340-340

2018

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Regulation of the Hypoxia-inducible Transcription Factor 1α by the Ubiquitin-Proteasome Pathway

The Journal of biological chemistry, 1999-03, Vol.274 (10), p.6519-6525

1999

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Abstract LB-113: Immune-mediated anti-tumor activity with a clinical stage BET bromodomain inhibitor ODM-207 in pre-clinical models

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.LB-113-LB-113

2017

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ODM-204: A novel dual inhibitor of CYP17A1 and androgen receptor for the treatment of castration-resistant prostate cancer—Preclinical data

Journal of clinical oncology, 2015-03, Vol.33 (7_suppl), p.221-221

2015

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Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1 alpha

The EMBO journal, 1998-11, Vol.17 (22), p.6573-6586

1998

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ODM-204, a novel dual inhibitor of CYP17A1 and androgen receptor for the treatment of castration-resistant prostate cancer

Journal of clinical oncology, 2016-01, Vol.34 (2_suppl), p.230-230

2016

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Abstract 4649: ODM-207, a novel BET-bromodomain inhibitor as a therapeutic approach for the treatment of prostate and breast cancer

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.4649-4649

2016

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Abstract 118: Targeting cancer with a novel BET bromodomain inhibitor ODM-207

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.118-118

2017

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Evolution of fungal tuberculosis necrotizing toxin (TNT) domain‐containing enzymes reveals divergent adaptations to enhance NAD cleavage

Protein science, 2024-07, Vol.33 (7), p.e5071-n/a

2024

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Health promotion and behavioral approaches in the prevention of periodontal disease in children and adolescents

Periodontology 2000, 2001-06, Vol.26 (1), p.135-145

Kallio, Pekka J.

2001

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Structural and functional dissection of Toxoplasma gondii armadillo repeats only protein

Journal of cell science, 2016-03, Vol.129 (5), p.1031-1045

2016

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Structure-guided discovery of 1,3,5 tri-substituted benzenes as potent and selective matriptase inhibitors exhibiting in vivo antitumor efficacy

Bioorganic & medicinal chemistry, 2014-06, Vol.22 (12), p.3187-3203

2014

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Ellipsoid Segmentation Model for Analyzing Light-Attenuated 3D Confocal Image Stacks of Fluorescent Multi-Cellular Spheroids

PloS one, 2016-06, Vol.11 (6), p.e0156942-e0156942

2016

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Discovery of ODM-201, a new-generation androgen receptor inhibitor targeting resistance mechanisms to androgen signaling-directed prostate cancer therapies

ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity

Adrenals Contribute to Growth of Castration-Resistant VCaP Prostate Cancer Xenografts

Discovery and development of ODM-204: A Novel nonsteroidal compound for the treatment of castration-resistant prostate cancer by blocking the androgen receptor and inhibiting CYP17A1

High intratumoral dihydrotestosterone is associated with antiandrogen resistance in VCaP prostate cancer xenografts in castrated mice

Activation of Hypoxia-Inducible Factor 1α : Posttranscriptional Regulation and Conformational Change by Recruitment of the Arnt Transcription Factor

Three-dimensional models of cancer for pharmacology and cancer cell biology: Capturing tumor complexity in vitro/ex vivo

Scientific Basis of a Matrix Metalloproteinase-8 Specific Chair-side Test for Monitoring Periodontal and Peri-implant Health and Disease

Mutual Transcriptional Interference between RelA and Androgen Receptor

Abstract 674: ODM-201 - New generation androgen receptor inhibitor targeting resistance mechanisms to androgen signalling-directed prostate cancer therapies

Self-assessed bleeding in monitoring gingival health among adolescents

Abstract 3970: Therapeutic targeting of estrogen receptor positive breast cancer with the BET bromodomain inhibitor ODM-207

CYP11A1 inhibition as a therapeutic approach for the treatment of castration resistant prostate cancer

Regulation of the Hypoxia-inducible Transcription Factor 1α by the Ubiquitin-Proteasome Pathway

Abstract LB-113: Immune-mediated anti-tumor activity with a clinical stage BET bromodomain inhibitor ODM-207 in pre-clinical models

ODM-204: A novel dual inhibitor of CYP17A1 and androgen receptor for the treatment of castration-resistant prostate cancer—Preclinical data

Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1 alpha

ODM-204, a novel dual inhibitor of CYP17A1 and androgen receptor for the treatment of castration-resistant prostate cancer

Abstract 4649: ODM-207, a novel BET-bromodomain inhibitor as a therapeutic approach for the treatment of prostate and breast cancer

Abstract 118: Targeting cancer with a novel BET bromodomain inhibitor ODM-207

Evolution of fungal tuberculosis necrotizing toxin (TNT) domain‐containing enzymes reveals divergent adaptations to enhance NAD cleavage

Health promotion and behavioral approaches in the prevention of periodontal disease in children and adolescents

Structural and functional dissection of Toxoplasma gondii armadillo repeats only protein

Structure-guided discovery of 1,3,5 tri-substituted benzenes as potent and selective matriptase inhibitors exhibiting in vivo antitumor efficacy

Ellipsoid Segmentation Model for Analyzing Light-Attenuated 3D Confocal Image Stacks of Fluorescent Multi-Cellular Spheroids

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