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The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes

Diabetologia, 2003, Vol.46 (1), p.3-19

KAHN, S. E

2003

Volltextzugriff (PDF)

Visceral abdominal fat accumulation predicts the conversion of metabolically healthy obese subjects to an unhealthy phenotype

International Journal of Obesity, 2015-09, Vol.39 (9), p.1365-1370

2015

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Toxic oligomers and islet beta cell death: guilty by association or convicted by circumstantial evidence

Diabetologia, 2010-06, Vol.53 (6), p.1046-1056

2010

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beta cell lesion in type 2 diabetes: there has to be a primary functional abnormality

Diabetologia, 2009-06, Vol.52 (6), p.1003-1012

2009

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Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sex

Diabetologia, 2003-04, Vol.46 (4), p.459-469

2003

Volltextzugriff (PDF)

Experience of malignancies with oral glucose-lowering drugs in the randomised controlled ADOPT (A Diabetes Outcome Progression Trial) and RECORD (Rosiglitazone Evaluated for Cardiovascular Outcomes and Regulation of Glycaemia in Diabetes) clinical trials

Diabetologia, 2010-09, Vol.53 (9), p.1838-1845

2010

Volltextzugriff (PDF)

Oxidative stress is induced by islet amyloid formation and time-dependently mediates amyloid-induced beta cell apoptosis

Diabetologia, 2009-04, Vol.52 (4), p.626-635

2009

Volltextzugriff (PDF)

Cancer outcomes and all-cause mortality in adults allocated to metformin: systematic review and collaborative meta-analysis of randomised clinical trials

Diabetologia, 2012-10, Vol.55 (10), p.2593-2603

2012

Volltextzugriff (PDF)

Steroid Sex Hormones, Sex Hormone–Binding Globulin, and Diabetes Incidence in the Diabetes Prevention Program

The journal of clinical endocrinology and metabolism, 2015-10, Vol.100 (10), p.3778-3786

2015

Volltextzugriff (PDF)

cJUN N-terminal kinase (JNK) activation mediates islet amyloid-induced beta cell apoptosis in cultured human islet amyloid polypeptide transgenic mouse islets

Diabetologia, 2012-01, Vol.55 (1), p.166-174

2012

Volltextzugriff (PDF)

Assessing gene-treatment interactions at the FTO and INSIG2 loci on obesity-related traits in the Diabetes Prevention Program

Diabetologia, 2008-12, Vol.51 (12), p.2214-2223

2008

Volltextzugriff (PDF)

FTO predicts weight regain in the Look AHEAD clinical trial

International Journal of Obesity, 2013-12, Vol.37 (12), p.1545-1552

2013

Volltextzugriff (PDF)

Exendin-4 increases islet amyloid deposition but offsets the resultant beta cell toxicity in human islet amyloid polypeptide transgenic mouse islets

Diabetologia, 2011-07, Vol.54 (7), p.1756-1765

2011

Volltextzugriff (PDF)

Obesity induced by a high-fat diet is associated with reduced brain insulin transport in dogs

Diabetes (New York, N.Y.), 2000-09, Vol.49 (9), p.1525-1533

2000

Volltextzugriff (PDF)

Islet amyloid: a long-recognized but underappreciated pathological feature of type 2 diabetes

Diabetes (New York, N.Y.), 1999-02, Vol.48 (2), p.241

1999

Volltextzugriff (PDF)

Resistin is not associated with insulin sensitivity or the metabolic syndrome in humans

Diabetologia, 2005-11, Vol.48 (11), p.2330-2333

2005

Volltextzugriff (PDF)

Within-subject variability of measures of beta cell function derived from a 2 h OGTT: implications for research studies

Diabetologia, 2007-12, Vol.50 (12), p.2516-2525

2007

Volltextzugriff (PDF)

Amyloid formation results in recurrence of hyperglycaemia following transplantation of human IAPP transgenic mouse islets

Diabetologia, 2009, Vol.52 (1), p.145-153

2009

Volltextzugriff (PDF)

Adiponectin and beta cell dysfunction in gestational diabetes : pathophysiological implications

Diabetologia, 2005-05, Vol.48 (5), p.993-1001

2005

Volltextzugriff (PDF)

Dietary-fat-induced obesity in mice results in beta cell hyperplasia but not increased insulin release : evidence for specificity of impaired beta cell adaptation

Diabetologia, 2005-07, Vol.48 (7), p.1350-1358

2005

Volltextzugriff (PDF)

Amyloid formation in human IAPP transgenic mouse islets and pancreas, and human pancreas, is not associated with endoplasmic reticulum stress

Diabetologia, 2009-06, Vol.52 (6), p.1102-1111

2009

Volltextzugriff (PDF)

Subcutaneous thigh fat area is unrelated to risk of type 2 diabetes in a prospective study of Japanese Americans

Diabetologia, 2011-11, Vol.54 (11), p.2795-2800

2011

Volltextzugriff (PDF)

Common variants in genes encoding adiponectin (ADIPOQ) and its receptors (ADIPOR1/2), adiponectin concentrations, and diabetes incidence in the Diabetes Prevention Program

Diabetic medicine, 2012-12, Vol.29 (12), p.1579-1588

2012

Volltextzugriff (PDF)

Altered body composition in type 2 diabetes mellitus

International Journal of Obesity, 2008-05, Vol.32 (5), p.780-787

2008

Volltextzugriff (PDF)

beta-cell dysfunction and failure in type 2 diabetes: potential mechanisms

Diabetes (New York, N.Y.), 2001-02, Vol.50 (suppl 1), p.S160-S163

2001

Volltextzugriff (PDF)

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The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes

Visceral abdominal fat accumulation predicts the conversion of metabolically healthy obese subjects to an unhealthy phenotype

Toxic oligomers and islet beta cell death: guilty by association or convicted by circumstantial evidence

beta cell lesion in type 2 diabetes: there has to be a primary functional abnormality

Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sex

Experience of malignancies with oral glucose-lowering drugs in the randomised controlled ADOPT (A Diabetes Outcome Progression Trial) and RECORD (Rosiglitazone Evaluated for Cardiovascular Outcomes and Regulation of Glycaemia in Diabetes) clinical trials

Oxidative stress is induced by islet amyloid formation and time-dependently mediates amyloid-induced beta cell apoptosis

Cancer outcomes and all-cause mortality in adults allocated to metformin: systematic review and collaborative meta-analysis of randomised clinical trials

Steroid Sex Hormones, Sex Hormone–Binding Globulin, and Diabetes Incidence in the Diabetes Prevention Program

cJUN N-terminal kinase (JNK) activation mediates islet amyloid-induced beta cell apoptosis in cultured human islet amyloid polypeptide transgenic mouse islets

Assessing gene-treatment interactions at the FTO and INSIG2 loci on obesity-related traits in the Diabetes Prevention Program

FTO predicts weight regain in the Look AHEAD clinical trial

Exendin-4 increases islet amyloid deposition but offsets the resultant beta cell toxicity in human islet amyloid polypeptide transgenic mouse islets

Obesity induced by a high-fat diet is associated with reduced brain insulin transport in dogs

Islet amyloid: a long-recognized but underappreciated pathological feature of type 2 diabetes

Resistin is not associated with insulin sensitivity or the metabolic syndrome in humans

Within-subject variability of measures of beta cell function derived from a 2 h OGTT: implications for research studies

Amyloid formation results in recurrence of hyperglycaemia following transplantation of human IAPP transgenic mouse islets

Adiponectin and beta cell dysfunction in gestational diabetes : pathophysiological implications

Dietary-fat-induced obesity in mice results in beta cell hyperplasia but not increased insulin release : evidence for specificity of impaired beta cell adaptation

Amyloid formation in human IAPP transgenic mouse islets and pancreas, and human pancreas, is not associated with endoplasmic reticulum stress

Subcutaneous thigh fat area is unrelated to risk of type 2 diabetes in a prospective study of Japanese Americans

Common variants in genes encoding adiponectin (ADIPOQ) and its receptors (ADIPOR1/2), adiponectin concentrations, and diabetes incidence in the Diabetes Prevention Program

Altered body composition in type 2 diabetes mellitus

beta-cell dysfunction and failure in type 2 diabetes: potential mechanisms

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