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Metabolically healthy and unhealthy obese – the 2013 Stock Conference report

Obesity reviews, 2014-09, Vol.15 (9), p.697-708

2014

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3-Hydroxyisobutyrate, A Strong Marker of Insulin Resistance in Type 2 Diabetes and Obesity That Modulates White and Brown Adipocyte Metabolism

Diabetes (New York, N.Y.), 2020-09, Vol.69 (9), p.1903-1916

2020

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The role of insulin and IGF-1 signaling in longevity

Cellular and molecular life sciences : CMLS, 2005-02, Vol.62 (3), p.320-343

2005

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Insulin receptor signaling in normal and insulin-resistant states

Cold Spring Harbor perspectives in biology, 2014-01, Vol.6 (1), p.a009191-a009191

2014

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Essential Role of IGFIR in the Onset of Male Brown Fat Thermogenic Function: Regulation of Glucose Homeostasis by Differential Organ-Specific Insulin Sensitivity

Endocrinology (Philadelphia), 2016-04, Vol.157 (4), p.1495-1511

2016

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Role of Brain Insulin Receptor in Control of Body Weight and Reproduction

Science (American Association for the Advancement of Science), 2000-09, Vol.289 (5487), p.2122-2125

2000

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Role of atypical protein kinase C in activation of sterol regulatory element binding protein-1c and nuclear factor kappa B (NFκB) in liver of rodents used as a model of diabetes, and relationships to hyperlipidaemia and insulin resistance

Diabetologia, 2009-06, Vol.52 (6), p.1197-1207

2009

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Genotype-phenotype relationships in Berardinelli-Seip congenital lipodystrophy

Journal of medical genetics, 2002-10, Vol.39 (10), p.722-733

2002

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The insulin signaling system

The Journal of biological chemistry, 1994-01, Vol.269 (1), p.1-4

1994

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Activation of the hexosamine pathway by glucosamine in vivo induces insulin resistance of early postreceptor insulin signaling events in skeletal muscle

Diabetes (New York, N.Y.), 1999-08, Vol.48 (8), p.1562-1571

1999

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Obesity Associated with a Mutation in a Genetic Regulator of Adipocyte Differentiation

The New England journal of medicine, 1998-10, Vol.339 (14), p.953-959

1998

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Insulin down-regulates insulin receptor substrate-2 expression through the phosphatidylinositol 3-kinase/Akt pathway

Journal of endocrinology, 2003-11, Vol.179 (2), p.253-266

2003

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Extended Longevity in Mice Lacking the Insulin Receptor in Adipose Tissue

Science (American Association for the Advancement of Science), 2003-01, Vol.299 (5606), p.572-574

2003

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Insulin signalling and the regulation of glucose and lipid metabolism

Nature (London), 2001-12, Vol.414 (6865), p.799-806

2001

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Bidirectional modulation of insulin action by amino acids

The Journal of clinical investigation, 1998-04, Vol.101 (7), p.1519-1529

1998

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Suppressor of Cytokine Signaling 1 (SOCS-1) and SOCS-3 Cause Insulin Resistance through Inhibition of Tyrosine Phosphorylation of Insulin Receptor Substrate Proteins by Discrete Mechanisms

Molecular and Cellular Biology, 2004-06, Vol.24 (12), p.5434-5446

2004

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Glucose toxicity and the development of diabetes in mice with muscle-specific inactivation of GLUT4

The Journal of clinical investigation, 2001-07, Vol.108 (1), p.153-160

2001

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Modulation in insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats

The Journal of clinical investigation, 1993-10, Vol.92 (4), p.2065-2072

1993

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Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression

Nature genetics, 1999-01, Vol.21 (1), p.133-137

1999

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Angiotensin II inhibits insulin signaling in aortic smooth muscle cells at multiple levels. A potential role for serine phosphorylation in insulin/angiotensin II crosstalk

The Journal of clinical investigation, 1997-11, Vol.100 (9), p.2158-2169

1997

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Evidence for a Circulating Islet Cell Growth Factor in Insulin-Resistant States

Proceedings of the National Academy of Sciences - PNAS, 2001-06, Vol.98 (13), p.7475-7480

2001

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Differential regulation of insulin receptor substrates-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse

The Journal of clinical investigation, 1997-12, Vol.100 (12), p.3164-3172

1997

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Essential Role of Insulin Receptor Substrate 1 in Differentiation of Brown Adipocytes

Molecular and Cellular Biology, 2001-01, Vol.21 (1), p.319-329

2001

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Adipose Tissue Selective Insulin Receptor Knockout Protects against Obesity and Obesity-Related Glucose Intolerance

Developmental cell, 2002-07, Vol.3 (1), p.25-38

2002

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Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

Molecular and Cellular Biology, 1994-07, Vol.14 (7), p.4902-4911

1994

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Metabolically healthy and unhealthy obese – the 2013 Stock Conference report

3-Hydroxyisobutyrate, A Strong Marker of Insulin Resistance in Type 2 Diabetes and Obesity That Modulates White and Brown Adipocyte Metabolism

The role of insulin and IGF-1 signaling in longevity

Insulin receptor signaling in normal and insulin-resistant states

Essential Role of IGFIR in the Onset of Male Brown Fat Thermogenic Function: Regulation of Glucose Homeostasis by Differential Organ-Specific Insulin Sensitivity

Role of Brain Insulin Receptor in Control of Body Weight and Reproduction

Role of atypical protein kinase C in activation of sterol regulatory element binding protein-1c and nuclear factor kappa B (NFκB) in liver of rodents used as a model of diabetes, and relationships to hyperlipidaemia and insulin resistance

Genotype-phenotype relationships in Berardinelli-Seip congenital lipodystrophy

The insulin signaling system

Activation of the hexosamine pathway by glucosamine in vivo induces insulin resistance of early postreceptor insulin signaling events in skeletal muscle

Obesity Associated with a Mutation in a Genetic Regulator of Adipocyte Differentiation

Insulin down-regulates insulin receptor substrate-2 expression through the phosphatidylinositol 3-kinase/Akt pathway

Extended Longevity in Mice Lacking the Insulin Receptor in Adipose Tissue

Insulin signalling and the regulation of glucose and lipid metabolism

Bidirectional modulation of insulin action by amino acids

Suppressor of Cytokine Signaling 1 (SOCS-1) and SOCS-3 Cause Insulin Resistance through Inhibition of Tyrosine Phosphorylation of Insulin Receptor Substrate Proteins by Discrete Mechanisms

Glucose toxicity and the development of diabetes in mice with muscle-specific inactivation of GLUT4

Modulation in insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats

Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression

Angiotensin II inhibits insulin signaling in aortic smooth muscle cells at multiple levels. A potential role for serine phosphorylation in insulin/angiotensin II crosstalk

Evidence for a Circulating Islet Cell Growth Factor in Insulin-Resistant States

Differential regulation of insulin receptor substrates-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse

Essential Role of Insulin Receptor Substrate 1 in Differentiation of Brown Adipocytes

Adipose Tissue Selective Insulin Receptor Knockout Protects against Obesity and Obesity-Related Glucose Intolerance

Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

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