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Fas and Perforin Pathways as Major Mechanisms of T Cell-Mediated Cytotoxicity

Science (American Association for the Advancement of Science), 1994-07, Vol.265 (5171), p.528-530

1994

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Differential Requirement for Caspase 9 in Apoptotic Pathways In Vivo

Cell, 1998-08, Vol.94 (3), p.339-352

1998

Volltextzugriff (PDF)

Interleukin 13 is secreted by and stimulates the growth of Hodgkin and Reed-Sternberg cells

The Journal of experimental medicine, 1999-06, Vol.189 (12), p.1939-1946

1999

Volltextzugriff (PDF)

Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice

The Journal of experimental medicine, 1997-10, Vol.186 (7), p.989-997

1997

Volltextzugriff (PDF)

The roles of perforin‐ and Fas‐dependent cytotoxicity in protection against cytopathic and noncytopathic viruses

European journal of immunology, 1995-12, Vol.25 (12), p.3256-3262

1995

Volltextzugriff (PDF)

Differential Contribution of Fas- and Perforin-Mediated Mechanisms to the Cell-Mediated Cytotoxic Activity of Naive and In Vivo-Primed Intestinal Intraepithelial Lymphocytes

The Journal of immunology (1950), 2000-01, Vol.164 (1), p.398-403

2000

Volltextzugriff (PDF)

Theiler’s Virus Infection of Perforin-Deficient Mice

Journal of Virology, 1998-05, Vol.72 (5), p.4515-4519

1998

Volltextzugriff (PDF)

TNF receptor 1-dependent beta cell toxicity as an effector pathway in autoimmune diabetes

The Journal of immunology (1950), 1999-04, Vol.162 (8), p.4598-4605

1999

Volltextzugriff (PDF)

Perforin dependence of natural killer cell‐mediated tumor control in vivo

European journal of immunology, 1995-12, Vol.25 (12), p.3514-3516

1995

Volltextzugriff (PDF)

Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes

Genes & development, 1998-03, Vol.12 (6), p.806-819

1998

Volltextzugriff (PDF)

Homeostatic regulation of CD8+ T cells by perforin

European journal of immunology, 1999-10, Vol.29 (10), p.3262-3272

1999

Volltextzugriff (PDF)

MOLECULAR MECHANISMS OF LYMPHOCYTE-MEDIATED CYTOTOXICITY AND THEIR ROLE IN IMMUNOLOGICAL PROTECTION AND PATHOGENESIS IN VIVO

Annual review of immunology, 1996-01, Vol.14 (1), p.207-232

1996

Volltextzugriff (PDF)

Cytotoxicity is mandatory for CD8(+) T cell-mediated contact hypersensitivity

The Journal of experimental medicine, 1999-03, Vol.189 (5), p.779-786

1999

Volltextzugriff (PDF)

Lymphocyte-mediated Cytotoxicity in vitro and in vivo: Mechanisms and Significance

Immunological reviews, 1995-08, Vol.146 (1), p.95-115

1995

Volltextzugriff (PDF)

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

Nature (London), 1994-05, Vol.369 (6475), p.31-37

1994

Volltextzugriff (PDF)

Decreased tumor surveillance in perforin-deficient mice

The Journal of experimental medicine, 1996-11, Vol.184 (5), p.1781-1790

1996

Volltextzugriff (PDF)

Different roles for cytotoxic T cells in the control of infections with cytopathic versus noncytopathic viruses

Current opinion in immunology, 1996-08, Vol.8 (4), p.472-477

1996

Volltextzugriff (PDF)

CD8Tc1 and Tc2 cells secrete distinct cytokine patterns in vitro and in vivo but induce similar inflammatory reactions

The Journal of immunology (1950), 1997-05, Vol.158 (9), p.4152

1997

Volltextzugriff (PDF)

Aplastic anemia rescued by exhaustion of cytokine-secreting CD8+ T cells in persistent infection with lymphocytic choriomeningitis virus

The Journal of experimental medicine, 1998-06, Vol.187 (11), p.1903-1920

1998

Volltextzugriff (PDF)

CD8+ T cell‐mediated protection against an intracellular bacterium by perforin‐dependent cytotoxicity

European journal of immunology, 1994-12, Vol.24 (12), p.3068-3072

1994

Volltextzugriff (PDF)

The transcription factor interferon regulatory factor-1 is essential for natural killer cell function in vivo

The Journal of experimental medicine, 1996-11, Vol.184 (5), p.2043-2048

1996

Volltextzugriff (PDF)

Perforin and Fas killing by CD8+ T cells limits their cytokine synthesis and proliferation

The Journal of experimental medicine, 1996-10, Vol.184 (4), p.1543-1547

1996

Volltextzugriff (PDF)

Development of insulitis without diabetes in transgenic mice lacking perforin-dependent cytotoxicity

The Journal of experimental medicine, 1996-05, Vol.183 (5), p.2143-2152

1996

Volltextzugriff (PDF)

Control of immunodeficiency and lymphoproliferation in mouse AIDS: studies of mice deficient in CD8+ T cells or perforin

Journal of Virology, 1997-03, Vol.71 (3), p.1808-1813

1997

Volltextzugriff (PDF)

The role of perforin protein in lymphocyte-mediated cytotoxicity

Kagi, David

1993

Volltextzugriff (PDF)

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Fas and Perforin Pathways as Major Mechanisms of T Cell-Mediated Cytotoxicity

Differential Requirement for Caspase 9 in Apoptotic Pathways In Vivo

Interleukin 13 is secreted by and stimulates the growth of Hodgkin and Reed-Sternberg cells

Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice

The roles of perforin‐ and Fas‐dependent cytotoxicity in protection against cytopathic and noncytopathic viruses

Differential Contribution of Fas- and Perforin-Mediated Mechanisms to the Cell-Mediated Cytotoxic Activity of Naive and In Vivo-Primed Intestinal Intraepithelial Lymphocytes

Theiler’s Virus Infection of Perforin-Deficient Mice

TNF receptor 1-dependent beta cell toxicity as an effector pathway in autoimmune diabetes

Perforin dependence of natural killer cell‐mediated tumor control in vivo

Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes

Homeostatic regulation of CD8+ T cells by perforin

MOLECULAR MECHANISMS OF LYMPHOCYTE-MEDIATED CYTOTOXICITY AND THEIR ROLE IN IMMUNOLOGICAL PROTECTION AND PATHOGENESIS IN VIVO

Cytotoxicity is mandatory for CD8(+) T cell-mediated contact hypersensitivity

Lymphocyte-mediated Cytotoxicity in vitro and in vivo: Mechanisms and Significance

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

Decreased tumor surveillance in perforin-deficient mice

Different roles for cytotoxic T cells in the control of infections with cytopathic versus noncytopathic viruses

CD8Tc1 and Tc2 cells secrete distinct cytokine patterns in vitro and in vivo but induce similar inflammatory reactions

Aplastic anemia rescued by exhaustion of cytokine-secreting CD8+ T cells in persistent infection with lymphocytic choriomeningitis virus

CD8+ T cell‐mediated protection against an intracellular bacterium by perforin‐dependent cytotoxicity

The transcription factor interferon regulatory factor-1 is essential for natural killer cell function in vivo

Perforin and Fas killing by CD8+ T cells limits their cytokine synthesis and proliferation

Development of insulitis without diabetes in transgenic mice lacking perforin-dependent cytotoxicity

Control of immunodeficiency and lymphoproliferation in mouse AIDS: studies of mice deficient in CD8+ T cells or perforin

The role of perforin protein in lymphocyte-mediated cytotoxicity

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