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Time‐to‐Event Analysis of Polatuzumab Vedotin‐Induced Peripheral Neuropathy to Assist in the Comparison of Clinical Dosing Regimens

CPT: pharmacometrics and systems pharmacology, 2017-06, Vol.6 (6), p.401-408

2017

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UVA/B-Induced Apoptosis in Human Melanocytes Involves Translocation of Cathepsins and Bcl-2 Family Members

Journal of investigative dermatology, 2006-05, Vol.126 (5), p.1119-1127

2006

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Evaluation of the effects of a metabotropic glutamate receptor 5-antagonist on electrically induced pain and central sensitization in healthy human volunteers

European journal of pain, 2013-11, Vol.17 (10), p.1465-1471

2013

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Modelling a spontaneously reported side effect by use of a markov mixed-effects model

Journal of pharmacokinetics and pharmacodynamics, 2005-04, Vol.32 (2), p.261-281

2005

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Abstract P5-20-07: A phase Ib dose-finding study of subcutaneous pertuzumab in combination with subcutaneous trastuzumab in healthy male volunteers and female patients with early breast cancer

Cancer research (Chicago, Ill.), 2018-02, Vol.78 (4_Supplement), p.P5-P5-20-07

2018

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Non-linear mixed effects modelling of positron emission tomography data for simultaneous estimation of radioligand kinetics and occupancy in healthy volunteers

NeuroImage (Orlando, Fla.), 2012-07, Vol.61 (4), p.849-856

2012

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Pharmacokinetic-pharmacodynamic modeling of fostamatinib efficacy on ACR20 to support dose selection in patients with rheumatoid arthritis (RA)

Journal of clinical pharmacology, 2015-03, Vol.55 (3), p.328-335

2015

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Norepinephrine transporter occupancy in the human brain after oral administration of quetiapine XR

The international journal of neuropsychopharmacology, 2013-11, Vol.16 (10), p.2235-2244

2013

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Estimation of drug receptor occupancy when non‐displaceable binding differs between brain regions – extending the simplified reference tissue model

British journal of clinical pharmacology, 2015-07, Vol.80 (1), p.116-127

2015

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Dose-dependent binding of AZD3783 to brain 5-HT1B receptors in non-human primates and human subjects: a positron emission tomography study with [11C]AZ10419369

Psychopharmacology, 2011-02, Vol.213 (2-3), p.533-545

2011

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Time-to-Event Analysis of Polatuzumab Vedotin-Induced Peripheral Neuropathy to Assist in the Comparison of Clinical Dosing Regimens: Time-to-Event Analysis

CPT: pharmacometrics and systems pharmacology, 2017-06, Vol.6 (6), p.401-408

2017

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Pharmacokinetic and exploratory exposure–response analysis of pertuzumab in patients with operable HER2-positive early breast cancer in the APHINITY study

Cancer chemotherapy and pharmacology, 2019-06, Vol.83 (6), p.1147-1158

2019

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Blood-brain barrier penetration of zolmitriptan- : Modelling of positron emission tomography data

Journal of pharmacokinetics and pharmacodynamics, 2006-02, Vol.33 (1), p.75-91

2006

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AZD5213, a novel histamine H3 antagonist permitting high daytime and low nocturnal H3 occupancy. A PET study in human subjects

INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2012, Vol.15, p.217

2012

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PIII-68NXY-059, a novel neuroprotectant, has no effect on pharmacokinetics of a single dose of digoxin in healthy subjects

Clinical pharmacology and therapeutics, 2006-02, Vol.79 (2), p.P77-P77

2006

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PIII-71NXY-059, a novel neuroprotectant, causes a limited and clinically insignificant reduction in the elimination of cefuroxime by competing for the organic anion transporter

Clinical pharmacology and therapeutics, 2006-02, Vol.79 (2), p.P78-P78

2006

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P.1.e.019 PET-measured occupancy of the norepinephrene transporter by extended release quetiapine fumarate (quetiapine XR) in brains of healthy subjects

European neuropsychopharmacology, 2008, Vol.18, p.S270-S270

2008

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PET-measured occupancy of the norepinephrine transporter by extended release quetiapine fumarate (Quetiapine XR) in brains of healthy subjects

BIOLOGICAL PSYCHIATRY, 2008, Vol.63 (7), p.106S

2008

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PET-measured occupancy of the norepinephrene transporter by extended release quetiapine fumarate (quetiapine XR) in brains of healthy subjects

EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2008, Vol.18, p.S270

2008

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PIII-71

Clinical pharmacology and therapeutics, 2006-02, Vol.79 (2), p.P78-P78

2006

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PIII-68

Clinical pharmacology and therapeutics, 2006-02, Vol.79 (2), p.P77-P77

2006

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CD4+ and CD8+ T cells in sentinel nodes exhibit distinct pattern of PD‐1, CD69, and HLA‐DR expression compared to tumor tissue in oral squamous cell carcinoma

Cancer science, 2021-03, Vol.112 (3), p.1048-1059

2021

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Alpha-synuclein biology in Lewy body diseases

Alzheimer's research & therapy, 2014-10, Vol.6 (5), p.73-73, Article 73

2014

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A prolonged innate systemic immune response in COVID-19

Scientific reports, 2022-06, Vol.12 (1), p.9915-9915, Article 9915

2022

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Inhibitors of mammalian target of rapamycin downregulate MYCN protein expression and inhibit neuroblastoma growth in vitro and in vivo

Oncogene, 2008-05, Vol.27 (20), p.2910-2922

2008

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Time‐to‐Event Analysis of Polatuzumab Vedotin‐Induced Peripheral Neuropathy to Assist in the Comparison of Clinical Dosing Regimens

UVA/B-Induced Apoptosis in Human Melanocytes Involves Translocation of Cathepsins and Bcl-2 Family Members

Evaluation of the effects of a metabotropic glutamate receptor 5-antagonist on electrically induced pain and central sensitization in healthy human volunteers

Modelling a spontaneously reported side effect by use of a markov mixed-effects model

Abstract P5-20-07: A phase Ib dose-finding study of subcutaneous pertuzumab in combination with subcutaneous trastuzumab in healthy male volunteers and female patients with early breast cancer

Non-linear mixed effects modelling of positron emission tomography data for simultaneous estimation of radioligand kinetics and occupancy in healthy volunteers

Pharmacokinetic-pharmacodynamic modeling of fostamatinib efficacy on ACR20 to support dose selection in patients with rheumatoid arthritis (RA)

Norepinephrine transporter occupancy in the human brain after oral administration of quetiapine XR

Estimation of drug receptor occupancy when non‐displaceable binding differs between brain regions – extending the simplified reference tissue model

Dose-dependent binding of AZD3783 to brain 5-HT1B receptors in non-human primates and human subjects: a positron emission tomography study with [11C]AZ10419369

Time-to-Event Analysis of Polatuzumab Vedotin-Induced Peripheral Neuropathy to Assist in the Comparison of Clinical Dosing Regimens: Time-to-Event Analysis

Pharmacokinetic and exploratory exposure–response analysis of pertuzumab in patients with operable HER2-positive early breast cancer in the APHINITY study

Blood-brain barrier penetration of zolmitriptan- : Modelling of positron emission tomography data

AZD5213, a novel histamine H3 antagonist permitting high daytime and low nocturnal H3 occupancy. A PET study in human subjects

PIII-68NXY-059, a novel neuroprotectant, has no effect on pharmacokinetics of a single dose of digoxin in healthy subjects

PIII-71NXY-059, a novel neuroprotectant, causes a limited and clinically insignificant reduction in the elimination of cefuroxime by competing for the organic anion transporter

P.1.e.019 PET-measured occupancy of the norepinephrene transporter by extended release quetiapine fumarate (quetiapine XR) in brains of healthy subjects

PET-measured occupancy of the norepinephrine transporter by extended release quetiapine fumarate (Quetiapine XR) in brains of healthy subjects

PET-measured occupancy of the norepinephrene transporter by extended release quetiapine fumarate (quetiapine XR) in brains of healthy subjects

PIII-71

PIII-68

CD4+ and CD8+ T cells in sentinel nodes exhibit distinct pattern of PD‐1, CD69, and HLA‐DR expression compared to tumor tissue in oral squamous cell carcinoma

Alpha-synuclein biology in Lewy body diseases

A prolonged innate systemic immune response in COVID-19

Inhibitors of mammalian target of rapamycin downregulate MYCN protein expression and inhibit neuroblastoma growth in vitro and in vivo

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