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Synthesis and Structure–Activity Relationship of Naphtho[1,2-b]furan-2-carboxamide Derivatives as Melanin Concentrating Hormone Receptor 1 Antagonists

Chemical and Pharmaceutical Bulletin, 2013/12/01, Vol.61(12), pp.1239-1247

2013

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Integrative genome-scale metabolic analysis of Vibrio vulnificus for drug targeting and discovery

Molecular systems biology, 2011-01, Vol.7 (1), p.460-n/a

2011

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KR-31761, a Novel K+ATP-Channel Opener, Exerts Cardioprotective Effects by Opening Both Mitochondrial K+ATP and Sarcolemmal K+ATP Channels in Rat Models of Ischemia/Reperfusion-Induced Heart Injury

Journal of Pharmacological Sciences, 2009, Vol.109(2), pp.222-232

2009

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A Novel Imidazo[1,5-b]isoquinolinone Derivative, U63A05, Inhibits Syk Activation in Mast Cells to Suppress IgE-Mediated Anaphylaxis in Mice

Journal of Pharmacological Sciences, 2011, Vol.115(4), pp.500-508

2011

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Cardioprotective effects of the novel Na+/H+ exchanger-1 inhibitor KR-32560 in a perfused rat heart model of global ischemia and reperfusion: Involvement of the Akt-GSK-3β cell survival pathway and antioxidant enzyme

Archives of Pharmacal Research, 2010, 33(8), , pp.1241-1251

2010

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Effects of sabiporide, a specific Na +/H + exchanger inhibitor, on neuronal cell death and brain ischemia

Brain research, 2005-11, Vol.1061 (1), p.67-71

2005

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Effects of KR-32570, a new sodium hydrogen exchanger inhibitor, on myocardial infarction and arrhythmias induced by ischemia and reperfusion

European journal of pharmacology, 2005-10, Vol.523 (1), p.101-108

2005

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KR-39038, a Novel GRK5 Inhibitor, Attenuates Cardiac Hypertrophy and Improves Cardiac Function in Heart Failure

Biomolecules & Therapeutics, 2020, 28(5), , pp.482-489

2020

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4-Substituted (benzo[ b]thiophene-2-carbonyl)guanidines as novel Na +/H + exchanger isoform-1 (NHE-1) inhibitors

Bioorganic & medicinal chemistry letters, 2005-06, Vol.15 (12), p.2998-3001

2005

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5-AIQ inhibits H2O2-induced apoptosis through reactive oxygen species scavenging and Akt/GSK-3β signaling pathway in H9c2 cardiomyocytes

Toxicology and applied pharmacology, 2013-04, Vol.268 (1), p.90-98

2013

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An increase in B cell apoptosis by interfering BAFF–BAFF-R interaction with small synthetic molecules

International immunopharmacology, 2011-10, Vol.11 (10), p.1523-1533

2011

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Cardioprotective effect of KR-33889, a novel PARP inhibitor, against oxidative stress-induced apoptosis in H9c2 cells and isolated rat hearts

Archives of Pharmacal Research, 2017, 40(5), , pp.640-654

2017

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KR-39038, a Novel GRK5 Inhibitor, Attenuates Cardiac Hypertrophy and Improves Cardiac Function in Heart Failure

Biomolecules & therapeutics, 2020-09, Vol.28 (5), p.482-489

2020

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A novel anti-neuroinflammatory pyridylimidazole compound KR-31360

Biochemical pharmacology, 2010-02, Vol.79 (4), p.596-609

2010

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KR-31762, a novel KATP channel opener, exerts cardioprotective effects by opening SarcKATP channels in rat models of ischemia/reperfusion-induced heart injury

Archives of Pharmacal Research, 2008, 31(4), , pp.482-489

2008

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Cardioprotective effects of bms-180448, a prototype mitokatp channel opener, and the role of salvage kinases, in the rat model of global ischemia and reperfusion heart injury

Archives of Pharmacal Research, 2007, 30(5), , pp.634-640

2007

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Cardioselective anti-ischemic ATP-sensitive potassium channel (K ATP) openers: benzopyranyl indoline and indole analogues

European journal of medicinal chemistry, 2003-05, Vol.38 (5), p.459-471

2003

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4-Arylphthalazin-1(2H)-one derivatives as potent antagonists of the melanin concentrating hormone receptor 1 (MCH-R1)

Bioorganic & medicinal chemistry letters, 2012-01, Vol.22 (1), p.427-430

2012

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Synthesis and biological evaluation of 3-substituted-benzofuran-2-carboxylic esters as a novel class of ischemic cell death inhibitors

Bioorganic & medicinal chemistry letters, 2010-11, Vol.20 (22), p.6362-6365

2010

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Effects of [5-(2-Methoxy-5-fluorophenyl)furan-2-ylcarbonyl]guanidine (KR-32560), a Novel Sodium/Hydrogen Exchanger-1 Inhibitor, on Myocardial Infarct Size and Ventricular Arrhythmias in a Rat Model of Ischemia/Reperfusion Heart Injury

Journal of Pharmacological Sciences, 2005, Vol.98(4), pp.439-449

2005

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A Novel Urotensin II Receptor Antagonist, KR-36996 Inhibits Smooth Muscle Proliferation through ERK/ROS Pathway

Biomolecules & therapeutics, 2017-05, Vol.25 (3), p.308-314

2017

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3-Substituted-(5-arylfuran-2-ylcarbonyl)guanidines as NHE-1 inhibitors

Bioorganic & medicinal chemistry letters, 2007-03, Vol.17 (5), p.1291-1295

2007

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KR33426, [2-(2,5-dichlorophenyl)-5-methyloxazol-4yl]carbonylguanidine, is a novel compound to be effective on mouse systemic lupus erythematosus

European journal of pharmacology, 2011-10, Vol.668 (3), p.459-466

2011

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Evaluation of anti-coccidial effects of 1-[4-(4-nitrophenoxy)phenyl]propane-1-one and identification of its potential target proteins in Toxoplasma gondii

Archives of Pharmacal Research, 2015, 38(5), , pp.752-760

2015

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Blockade of Urotensin II Receptor Prevents Vascular Dysfunction

Biomolecules & therapeutics, 2016-09, Vol.24 (5), p.523-528

2016

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Synthesis and Structure–Activity Relationship of Naphtho[1,2-b]furan-2-carboxamide Derivatives as Melanin Concentrating Hormone Receptor 1 Antagonists

Integrative genome-scale metabolic analysis of Vibrio vulnificus for drug targeting and discovery

KR-31761, a Novel K+ATP-Channel Opener, Exerts Cardioprotective Effects by Opening Both Mitochondrial K+ATP and Sarcolemmal K+ATP Channels in Rat Models of Ischemia/Reperfusion-Induced Heart Injury

A Novel Imidazo[1,5-b]isoquinolinone Derivative, U63A05, Inhibits Syk Activation in Mast Cells to Suppress IgE-Mediated Anaphylaxis in Mice

Cardioprotective effects of the novel Na+/H+ exchanger-1 inhibitor KR-32560 in a perfused rat heart model of global ischemia and reperfusion: Involvement of the Akt-GSK-3β cell survival pathway and antioxidant enzyme

Effects of sabiporide, a specific Na +/H + exchanger inhibitor, on neuronal cell death and brain ischemia

Effects of KR-32570, a new sodium hydrogen exchanger inhibitor, on myocardial infarction and arrhythmias induced by ischemia and reperfusion

KR-39038, a Novel GRK5 Inhibitor, Attenuates Cardiac Hypertrophy and Improves Cardiac Function in Heart Failure

4-Substituted (benzo[ b]thiophene-2-carbonyl)guanidines as novel Na +/H + exchanger isoform-1 (NHE-1) inhibitors

5-AIQ inhibits H2O2-induced apoptosis through reactive oxygen species scavenging and Akt/GSK-3β signaling pathway in H9c2 cardiomyocytes

An increase in B cell apoptosis by interfering BAFF–BAFF-R interaction with small synthetic molecules

Cardioprotective effect of KR-33889, a novel PARP inhibitor, against oxidative stress-induced apoptosis in H9c2 cells and isolated rat hearts

KR-39038, a Novel GRK5 Inhibitor, Attenuates Cardiac Hypertrophy and Improves Cardiac Function in Heart Failure

A novel anti-neuroinflammatory pyridylimidazole compound KR-31360

KR-31762, a novel KATP channel opener, exerts cardioprotective effects by opening SarcKATP channels in rat models of ischemia/reperfusion-induced heart injury

Cardioprotective effects of bms-180448, a prototype mitokatp channel opener, and the role of salvage kinases, in the rat model of global ischemia and reperfusion heart injury

Cardioselective anti-ischemic ATP-sensitive potassium channel (K ATP) openers: benzopyranyl indoline and indole analogues

4-Arylphthalazin-1(2H)-one derivatives as potent antagonists of the melanin concentrating hormone receptor 1 (MCH-R1)

Synthesis and biological evaluation of 3-substituted-benzofuran-2-carboxylic esters as a novel class of ischemic cell death inhibitors

Effects of [5-(2-Methoxy-5-fluorophenyl)furan-2-ylcarbonyl]guanidine (KR-32560), a Novel Sodium/Hydrogen Exchanger-1 Inhibitor, on Myocardial Infarct Size and Ventricular Arrhythmias in a Rat Model of Ischemia/Reperfusion Heart Injury

A Novel Urotensin II Receptor Antagonist, KR-36996 Inhibits Smooth Muscle Proliferation through ERK/ROS Pathway

3-Substituted-(5-arylfuran-2-ylcarbonyl)guanidines as NHE-1 inhibitors

KR33426, [2-(2,5-dichlorophenyl)-5-methyloxazol-4yl]carbonylguanidine, is a novel compound to be effective on mouse systemic lupus erythematosus

Evaluation of anti-coccidial effects of 1-[4-(4-nitrophenoxy)phenyl]propane-1-one and identification of its potential target proteins in Toxoplasma gondii

Blockade of Urotensin II Receptor Prevents Vascular Dysfunction

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