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Phase I Evaluation of ISIS 3521, an Antisense Oligodeoxynucleotide to Protein Kinase C-Alpha, in Patients With Advanced Cancer

Journal of clinical oncology, 1999-11, Vol.17 (11), p.3586-3595

1999

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The importance of nef in the induction of human immunodeficiency virus type 1 replication from primary quiescent CD4 lymphocytes

The Journal of experimental medicine, 1994, Vol.179 (1), p.115-123

1994

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Phase I Study of an Antisense Oligonucleotide to Protein Kinase C-α (ISIS 3521/CGP 64128A ) in Patients with Cancer

Clinical cancer research, 1999-11, Vol.5 (11), p.3357-3363

1999

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Phase I Clinical/Pharmacokinetic and Pharmacodynamic Trial of the c-raf-1 Antisense Oligonucleotide ISIS 5132 (CGP 69846A)

Journal of clinical oncology, 1999-07, Vol.17 (7), p.2227-2236

1999

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A Phase I trial of h‐ras antisense oligonucleotide ISIS 2503 administered as a continuous intravenous infusion in patients with advanced carcinoma

Cancer, 2001-09, Vol.92 (5), p.1265-1271

2001

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A Phase I Trial of c-Raf Kinase Antisense Oligonucleotide ISIS 5132 Administered as a Continuous Intravenous Infusion in Patients with Advanced Cancer

Clinical cancer research, 2000-05, Vol.6 (5), p.1626

2000

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Phase I Trial of ISIS 5132, an Antisense Oligonucleotide Inhibitor of c-raf-1, Administered by 24-hour Weekly Infusion to Patients with Advanced Cancer

Clinical cancer research, 2001-05, Vol.7 (5), p.1214-1220

2001

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Introduction and Expression of the Bacterial PaeR7 Methylase Gene in Mammalian Cells

Proceedings of the National Academy of Sciences - PNAS, 1986-10, Vol.83 (20), p.7713-7717

1986

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Analysis of substrate specificity of the PaeR7 endonuclease : effect of base methylation on the kinetics of cleavage

Nucleic acids research, 1990-09, Vol.18 (17), p.5063-5068

1990

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Amino acid sequence of the precursor of rat liver alpha 2 micro-globulin

The Journal of biological chemistry, 1981-04, Vol.256 (8), p.3634-3636

1981

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A phase I trial of an antisense inhibitor of hepatitis C virus (ISIS 14803), administered to chronic hepatitis C patients

Journal of hepatology, 2006-01, Vol.44 (1), p.88-96

2006

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A phase I trial of aprinocarsen (ISIS 3521/LY900003), an antisense inhibitor of protein kinase C-alpha administered as a 24-hour weekly infusion schedule in patients with advanced cancer

Investigational new drugs, 2005-10, Vol.23 (5), p.467-477

2005

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Target amplification systems in nucleic acid-based diagnostic approaches

American biotechnology laboratory, 1990-10, Vol.8 (13), p.14

1990

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Introduction and expression of the bacterial PaeR7 restriction endonuclease gene in mouse cells containing the PaeR7 methylase

Nucleic acids research, 1988-12, Vol.16 (24), p.11489-11506

1988

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Toward antisense oligonucleotide therapy for cancer: ISIS compounds in clinical development

Current opinion in molecular therapeutics, 1999-06, Vol.1 (3), p.372

1999

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Mutational analysis of the cloned chicken thymidine kinase gene

Journal of molecular and applied genetics, 1983, Vol.2 (2), p.191

1983

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Examination of newly synthesized DNA in Escherichia coli

Molecular & general genetics, 1979-01, Vol.173 (1), p.85-93

1979

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nucleotide sequence of the chicken thymidine kinase gene and the relationship of its predicted polypeptide to that of the vaccinia virus thymidine kinase

Nucleic acids research, 1984-05, Vol.12 (9), p.3959-3971

1984

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Stabilization of a degradable protein by its overexpression in Escherichia coli

Gene, 1981-06, Vol.14 (1-2), p.121-130

1981

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Introduction and expression of the bacterial PaeaR7 restriction endonuclease gene in mouse cells containing the PaeR7 methylase

Nucleic acids research, 1988, Vol.16 (24), p.11489-11506

1988

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In vitro and in vivo manipulations of bacteriophage Mu DNA: Cloning of Mu ends and construction of mini-Mu's carrying selectable markers

Gene, 1981, Vol.13 (1), p.37-46

1981

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What Comes First? Multitissue Involvement Leading to Radiographic Osteoarthritis: Magnetic Resonance Imaging–Based Trajectory Analysis Over Four Years in the Osteoarthritis Initiative

Arthritis & rheumatology (Hoboken, N.J.), 2015-05, Vol.67 (8), p.2085-2096

2015

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MRI-based screening for structural definition of eligibility in clinical DMOAD trials: Rapid OsteoArthritis MRI Eligibility Score (ROAMES)

Osteoarthritis and cartilage, 2020-01, Vol.28 (1), p.71-81

2020

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Associations of components of sarcopenia with risk of fracture in the Osteoporotic Fractures in Men (MrOS) study

Osteoporosis international, 2022-08, Vol.33 (8), p.1815-1821

2022

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Phase I Evaluation of ISIS 3521, an Antisense Oligodeoxynucleotide to Protein Kinase C-Alpha, in Patients With Advanced Cancer

The importance of nef in the induction of human immunodeficiency virus type 1 replication from primary quiescent CD4 lymphocytes

Phase I Study of an Antisense Oligonucleotide to Protein Kinase C-α (ISIS 3521/CGP 64128A ) in Patients with Cancer

Phase I Clinical/Pharmacokinetic and Pharmacodynamic Trial of the c-raf-1 Antisense Oligonucleotide ISIS 5132 (CGP 69846A)

Inotersen Treatment for Patients with Hereditary Transthyretin Amyloidosis

A Phase I trial of h‐ras antisense oligonucleotide ISIS 2503 administered as a continuous intravenous infusion in patients with advanced carcinoma

A Phase I Trial of c-Raf Kinase Antisense Oligonucleotide ISIS 5132 Administered as a Continuous Intravenous Infusion in Patients with Advanced Cancer

Phase I Trial of ISIS 5132, an Antisense Oligonucleotide Inhibitor of c-raf-1, Administered by 24-hour Weekly Infusion to Patients with Advanced Cancer

Introduction and Expression of the Bacterial PaeR7 Methylase Gene in Mammalian Cells

Analysis of substrate specificity of the PaeR7 endonuclease : effect of base methylation on the kinetics of cleavage

Amino acid sequence of the precursor of rat liver alpha 2 micro-globulin

A phase I trial of an antisense inhibitor of hepatitis C virus (ISIS 14803), administered to chronic hepatitis C patients

A phase I trial of aprinocarsen (ISIS 3521/LY900003), an antisense inhibitor of protein kinase C-alpha administered as a 24-hour weekly infusion schedule in patients with advanced cancer

Target amplification systems in nucleic acid-based diagnostic approaches

Introduction and expression of the bacterial PaeR7 restriction endonuclease gene in mouse cells containing the PaeR7 methylase

Toward antisense oligonucleotide therapy for cancer: ISIS compounds in clinical development

Mutational analysis of the cloned chicken thymidine kinase gene

Examination of newly synthesized DNA in Escherichia coli

nucleotide sequence of the chicken thymidine kinase gene and the relationship of its predicted polypeptide to that of the vaccinia virus thymidine kinase

Stabilization of a degradable protein by its overexpression in Escherichia coli

Introduction and expression of the bacterial PaeaR7 restriction endonuclease gene in mouse cells containing the PaeR7 methylase

In vitro and in vivo manipulations of bacteriophage Mu DNA: Cloning of Mu ends and construction of mini-Mu's carrying selectable markers

What Comes First? Multitissue Involvement Leading to Radiographic Osteoarthritis: Magnetic Resonance Imaging–Based Trajectory Analysis Over Four Years in the Osteoarthritis Initiative

MRI-based screening for structural definition of eligibility in clinical DMOAD trials: Rapid OsteoArthritis MRI Eligibility Score (ROAMES)

Associations of components of sarcopenia with risk of fracture in the Osteoporotic Fractures in Men (MrOS) study

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