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Design of antisense oligonucleotides stabilized by locked nucleic acids

Nucleic acids research, 2002-05, Vol.30 (9), p.1911-1918

2002

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microRNA122-regulated transgene expression increases specificity of cardiac gene transfer upon intravenous delivery of AAV9 vectors

Gene therapy, 2011-02, Vol.18 (2), p.199-209

2011

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Ribozyme- and deoxyribozyme-strategies for medical applications

Current drug targets, 2004-11, Vol.5 (8), p.667-681

2004

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Silencing of vanilloid receptor TRPV1 by RNAi reduces neuropathic and visceral pain in vivo

Biochemical and biophysical research communications, 2006-11, Vol.350 (1), p.238-243

2006

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Comparison of different antisense strategies in mammalian cells using locked nucleic acids, 2'-O-methyl RNA, phosphorothioates and small interfering RNA

Nucleic acids research, 2003-06, Vol.31 (12), p.3185-3193

2003

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Expression of an engineered soluble coxsackievirus and adenovirus receptor by a dimeric AAV9 vector inhibits adenovirus infection in mice

Gene therapy, 2015-06, Vol.22 (6), p.458-466

2015

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Antisense technologies. Improvement through novel chemical modifications

European journal of biochemistry, 2003-04, Vol.270 (8), p.1628-1644

Kurreck, Jens

2003

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Investigation of TRPV1 loss-of-function phenotypes in transgenic shRNA expressing and knockout mice

Molecular and cellular neuroscience, 2008-03, Vol.37 (3), p.579-589

2008

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Highly efficient and specific modulation of cardiac calcium homeostasis by adenovector-derived short hairpin RNA targeting phospholamban

Gene therapy, 2007-02, Vol.14 (3), p.211-218

2007

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Coxsackievirus B3 and adenovirus infections of cardiac cells are efficiently inhibited by vector-mediated RNA interference targeting their common receptor

Gene therapy, 2007-06, Vol.14 (12), p.960-971

2007

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Oligonucleotide-based antiviral strategies

Handbook of experimental pharmacology, 2006 (173), p.261

2006

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Novel effects of Foxo3a on immune system and cardiac remodeling after myocardial infarction

European heart journal, 2020-11, Vol.41 (Supplement_2)

2020

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Foxo3a and cardiac myofibroblast transdifferentiation after myocardial infarction

European heart journal, 2023-11, Vol.44 (Supplement_2)

2023

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Therapeutic oligonucleotides

Kurreck, Jens

1, 2008

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Local RNA Target Structure Influences siRNA Efficacy: Systematic Analysis of Intentionally Designed Binding Regions

Journal of molecular biology, 2005-05, Vol.348 (4), p.883-893

2005

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Differentiating the functional role of hypoxia‐inducible factor (HIF)‐1α and HIF‐2α (EPAS‐1) by the use of RNA interference: erythropoietin is a HIF‐2α target gene in Hep3B and Kelly cells

The FASEB journal, 2004-09, Vol.18 (12), p.1462-1464

2004

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Application of locked nucleic acids to improve aptamer in vivo stability and targeting function

Nucleic acids research, 2004-01, Vol.32 (19), p.5757-5765

2004

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RNA interference in pain research

Journal of neurochemistry, 2006-10, Vol.99 (2), p.371-380

2006

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RNA interference-based functional knockdown of the voltage-gated potassium channel Kv7.2 in dorsal root ganglion neurons after in vitro and in vivo gene transfer by adeno-associated virus vectors

Molecular pain, 2018-01, Vol.14, p.1744806917749669-1744806917749669

2018

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Biochemical characterization of the vanilloid receptor 1 expressed in a dorsal root ganglia derived cell line

European journal of biochemistry, 2001-11, Vol.268 (21), p.5489-5496

2001

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RNA cleaving '10-23' DNAzymes with enhanced stability and activity

Nucleic acids research, 2003-10, Vol.31 (20), p.5982-5992

2003

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Site-directed mutagenesis of serine 158 demonstrates its role in spinach leaf sucrose-phosphate synthase modulation

The Plant journal : for cell and molecular biology, 1999-02, Vol.17 (4), p.407-413

1999

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Antinociceptive effect of antisense oligonucleotides against the vanilloid receptor VR1/TRPV1

Neurochemistry international, 2007, Vol.50 (1), p.281-290

2007

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Deletion analysis in the catalytic region of the 10–23 DNA enzyme

FEBS letters, 2005-01, Vol.579 (2), p.554-558

2005

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Sequence requirements in the catalytic core of the "10-23" DNA enzyme

The Journal of biological chemistry, 2002-10, Vol.277 (43), p.40617-40622

2002

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Design of antisense oligonucleotides stabilized by locked nucleic acids

microRNA122-regulated transgene expression increases specificity of cardiac gene transfer upon intravenous delivery of AAV9 vectors

Ribozyme- and deoxyribozyme-strategies for medical applications

Silencing of vanilloid receptor TRPV1 by RNAi reduces neuropathic and visceral pain in vivo

Comparison of different antisense strategies in mammalian cells using locked nucleic acids, 2'-O-methyl RNA, phosphorothioates and small interfering RNA

Expression of an engineered soluble coxsackievirus and adenovirus receptor by a dimeric AAV9 vector inhibits adenovirus infection in mice

Antisense technologies. Improvement through novel chemical modifications

Investigation of TRPV1 loss-of-function phenotypes in transgenic shRNA expressing and knockout mice

Highly efficient and specific modulation of cardiac calcium homeostasis by adenovector-derived short hairpin RNA targeting phospholamban

Coxsackievirus B3 and adenovirus infections of cardiac cells are efficiently inhibited by vector-mediated RNA interference targeting their common receptor

Oligonucleotide-based antiviral strategies

Novel effects of Foxo3a on immune system and cardiac remodeling after myocardial infarction

Foxo3a and cardiac myofibroblast transdifferentiation after myocardial infarction

Therapeutic oligonucleotides

Local RNA Target Structure Influences siRNA Efficacy: Systematic Analysis of Intentionally Designed Binding Regions

Differentiating the functional role of hypoxia‐inducible factor (HIF)‐1α and HIF‐2α (EPAS‐1) by the use of RNA interference: erythropoietin is a HIF‐2α target gene in Hep3B and Kelly cells

Application of locked nucleic acids to improve aptamer in vivo stability and targeting function

RNA interference in pain research

RNA interference-based functional knockdown of the voltage-gated potassium channel Kv7.2 in dorsal root ganglion neurons after in vitro and in vivo gene transfer by adeno-associated virus vectors

Biochemical characterization of the vanilloid receptor 1 expressed in a dorsal root ganglia derived cell line

RNA cleaving '10-23' DNAzymes with enhanced stability and activity

Site-directed mutagenesis of serine 158 demonstrates its role in spinach leaf sucrose-phosphate synthase modulation

Antinociceptive effect of antisense oligonucleotides against the vanilloid receptor VR1/TRPV1

Deletion analysis in the catalytic region of the 10–23 DNA enzyme

Sequence requirements in the catalytic core of the "10-23" DNA enzyme

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