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Human gut microbiota influences drug-metabolizing enzyme hepatic Cyp3a: A human flora-associated mice study

The Journal of Toxicological Sciences, 2023, Vol.48(6), pp.333-343

2023

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YPC‐21661 and YPC‐22026, novel small molecules, inhibit ZNF143 activity in vitro and in vivo

Cancer science, 2017-05, Vol.108 (5), p.1042-1048

2017

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Perifosine, a Bioavailable Alkylphospholipid Akt Inhibitor, Exhibits Antitumor Activity in Murine Models of Cancer Brain Metastasis Through Favorable Tumor Exposure

Frontiers in oncology, 2021-11, Vol.11, p.754365-754365

2021

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Comparative studies of irinotecan-loaded polyethylene glycol-modified liposomes prepared using different PEG-modification methods

Biochimica et biophysica acta, 2012-11, Vol.1818 (11), p.2901-2907

2012

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PEGylated liposome IHL-305 markedly improved the survival of ovarian cancer peritoneal metastasis in mouse

BMC cancer, 2012-10, Vol.12 (1), p.462-462, Article 462

2012

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Pharmacokinetics of prolonged-release CPT-11-loaded microspheres in rats

Journal of controlled release, 2000-05, Vol.66 (2), p.159-175

2000

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Rapid deconjugation of SN-38 glucuronide and adsorption of released free SN-38 by intestinal microorganisms in rat

Oncology letters, 2012-03, Vol.3 (3), p.520-524

2012

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Involvement of UDP-glucuronosyltransferase activity in irinotecan-induced delayed-onset diarrhea in rats

Cancer chemotherapy and pharmacology, 2008-04, Vol.61 (4), p.595-605

2008

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Modified irinotecan hydrochloride (CPT-11) administration schedule improves induction of delayed-onset diarrhea in rats

Cancer chemotherapy and pharmacology, 2000, Vol.46 (3), p.211-220

2000

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Alleviation of side effects induced by irinotecan hydrochloride (CPT-11) in rats by intravenous infusion

Cancer chemotherapy and pharmacology, 2003-11, Vol.52 (5), p.349-360

2003

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Synthesis, Characterization, and Preliminary in Vivo Tests of New Poly(ethylene glycol) Conjugates of the Antitumor Agent 10-Amino-7-ethylcamptothecin

Journal of medicinal chemistry, 2004-02, Vol.47 (5), p.1280-1289

2004

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Streptomycin alleviates irinotecan-induced delayed-onset diarrhea in rats by a mechanism other than inhibition of β-glucuronidase activity in intestinal lumen

Cancer chemotherapy and pharmacology, 2011, Vol.67 (1), p.201-213

2011

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Organotin Perfluorooctanesulfonates as Air-Stable Lewis Acid Catalysts: Synthesis, Characterization, and Catalysis

Chemistry : a European journal, 2006-02, Vol.12 (6), p.1642-1647

2006

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Antitumor activity of IHL-305, a novel pegylated liposome containing irinotecan, in human xenograft models

Oncology reports, 2012-01, Vol.27 (1), p.189-197

2012

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Vibrio trachuri Sp. Nov., a New Species Isolated from Diseased Japanese Horse Mackerel

MICROBIOLOGY and IMMUNOLOGY, 1995, Vol.39(11), pp.831-837

1995

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A Cationic Distannoxane Catalyst. Synthesis and Applications to Carbon−Carbon Bond Forming Reactions

Organometallics, 2005-05, Vol.24 (11), p.2567-2569

2005

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Metabolism of irinotecan and its active metabolite SN-38 by intestinal microflora in rats

Oncology reports, 2008-10, Vol.20 (4), p.727-730

2008

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Streptomycin alleviates irinotecan-induced delayed-onset diarrhea in rats by a mechanism other than inhibition of [beta]-glucuronidase activity in intestinal lumen

Cancer chemotherapy and pharmacology, 2011-01, Vol.67 (1), p.201

2011

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No toxicity caused by organ accumulation of CPT-11 on multiple injections under clinical regimens in rats

Journal of toxicological sciences, 2000, Vol.25 (5), p.393-402

2000

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Rapid and Sensitive PCR Detection of Vibrio trachuri Pathogenic to Japanese Horse Mackerel (Trachurus japonicus)

MICROBIOLOGY and IMMUNOLOGY, 1995, Vol.39(12), pp.1003-1006

1995

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DNA Strand-Breaking Activities of Quinolone Antimicrobial Agents under Visible Light Irradiation

Biological and Pharmaceutical Bulletin, 1994/05/15, Vol.17(5), pp.654-657

1994

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Efficient and chemoselective N-acylation of 10-amino-7-ethyl camptothecin with poly(ethylene glycol)

Bioorganic & medicinal chemistry letters, 2004-04, Vol.14 (7), p.1803-1805

2004

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Synthesis, Characterization, and Preliminary in Vivo Tests of New Poly(ethylene glycol) Conjugates of the Antitumor Agent 10-Amino-7-ethylcamptothecin

Journal of medicinal chemistry, 2004-07, Vol.47 (14), p.3705-3705

2004

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Intravenous administration of irinotecan elevates the blood β-glucuronidase activity in rats

Cancer research (Chicago, Ill.), 1997-12, Vol.57 (23), p.5305-5308

1997

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NO TOXICITY CAUSED BY ORGAN ACCUMULATION OF CPT-11 ON MULTIPLE INJECTIONS UNDER CLINICAL REGIMENTS IN RATS

The Journal of Toxicological Sciences, 2000/12/25, Vol.25(5), pp.393-402

2000

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Human gut microbiota influences drug-metabolizing enzyme hepatic Cyp3a: A human flora-associated mice study

YPC‐21661 and YPC‐22026, novel small molecules, inhibit ZNF143 activity in vitro and in vivo

Perifosine, a Bioavailable Alkylphospholipid Akt Inhibitor, Exhibits Antitumor Activity in Murine Models of Cancer Brain Metastasis Through Favorable Tumor Exposure

Comparative studies of irinotecan-loaded polyethylene glycol-modified liposomes prepared using different PEG-modification methods

PEGylated liposome IHL-305 markedly improved the survival of ovarian cancer peritoneal metastasis in mouse

Pharmacokinetics of prolonged-release CPT-11-loaded microspheres in rats

Rapid deconjugation of SN-38 glucuronide and adsorption of released free SN-38 by intestinal microorganisms in rat

Involvement of UDP-glucuronosyltransferase activity in irinotecan-induced delayed-onset diarrhea in rats

Modified irinotecan hydrochloride (CPT-11) administration schedule improves induction of delayed-onset diarrhea in rats

Alleviation of side effects induced by irinotecan hydrochloride (CPT-11) in rats by intravenous infusion

Synthesis, Characterization, and Preliminary in Vivo Tests of New Poly(ethylene glycol) Conjugates of the Antitumor Agent 10-Amino-7-ethylcamptothecin

Streptomycin alleviates irinotecan-induced delayed-onset diarrhea in rats by a mechanism other than inhibition of β-glucuronidase activity in intestinal lumen

Organotin Perfluorooctanesulfonates as Air-Stable Lewis Acid Catalysts: Synthesis, Characterization, and Catalysis

Antitumor activity of IHL-305, a novel pegylated liposome containing irinotecan, in human xenograft models

Vibrio trachuri Sp. Nov., a New Species Isolated from Diseased Japanese Horse Mackerel

A Cationic Distannoxane Catalyst. Synthesis and Applications to Carbon−Carbon Bond Forming Reactions

Metabolism of irinotecan and its active metabolite SN-38 by intestinal microflora in rats

Streptomycin alleviates irinotecan-induced delayed-onset diarrhea in rats by a mechanism other than inhibition of [beta]-glucuronidase activity in intestinal lumen

No toxicity caused by organ accumulation of CPT-11 on multiple injections under clinical regimens in rats

Rapid and Sensitive PCR Detection of Vibrio trachuri Pathogenic to Japanese Horse Mackerel (Trachurus japonicus)

DNA Strand-Breaking Activities of Quinolone Antimicrobial Agents under Visible Light Irradiation

Efficient and chemoselective N-acylation of 10-amino-7-ethyl camptothecin with poly(ethylene glycol)

Synthesis, Characterization, and Preliminary in Vivo Tests of New Poly(ethylene glycol) Conjugates of the Antitumor Agent 10-Amino-7-ethylcamptothecin

Intravenous administration of irinotecan elevates the blood β-glucuronidase activity in rats

NO TOXICITY CAUSED BY ORGAN ACCUMULATION OF CPT-11 ON MULTIPLE INJECTIONS UNDER CLINICAL REGIMENTS IN RATS

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