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Early alterations in hippocampal perisomatic GABAergic synapses and network oscillations in a mouse model of Alzheimer's disease amyloidosis

PloS one, 2019-01, Vol.14 (1), p.e0209228-e0209228

2019

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Loss of Extrasynaptic Inhibitory Glycine Receptors in the Hippocampus of an AD Mouse Model Is Restored by Treatment with Artesunate

International journal of molecular sciences, 2023-02, Vol.24 (5), p.4623

2023

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Binding of gephyrin to microtubules is regulated by its phosphorylation at Ser270

Histochemistry and cell biology, 2021-07, Vol.156 (1), p.5-18

2021

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Gephyrin: a key regulatory protein of inhibitory synapses and beyond

Histochemistry and cell biology, 2018-11, Vol.150 (5), p.489-508

2018

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Another Use for a Proven Drug: Experimental Evidence for the Potential of Artemisinin and Its Derivatives to Treat Alzheimer's Disease

International journal of molecular sciences, 2024-04, Vol.25 (8), p.4165

2024

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Cyclin-dependent kinase 5 is involved in the phosphorylation of gephyrin and clustering of GABAA receptors at inhibitory synapses of hippocampal neurons

PloS one, 2014-08, Vol.9 (8), p.e104256

2014

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Evidence for a Tetrameric Structure of Recombinant NMDA Receptors

The Journal of neuroscience, 1998-04, Vol.18 (8), p.2954-2961

1998

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KCC2 knockdown impairs glycinergic synapse maturation in cultured spinal cord neurons

Histochemistry and cell biology, 2016-06, Vol.145 (6), p.637-646

2016

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Molecular Determinants of Agonist Discrimination by NMDA Receptor Subunits: Analysis of the Glutamate Binding Site on the NR2B Subunit

Neuron (Cambridge, Mass.), 1997-03, Vol.18 (3), p.493-503

1997

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Activity-dependent shedding of the NMDA receptor glycine binding site by matrix metalloproteinase 3: a PUTATIVE mechanism of postsynaptic plasticity

PloS one, 2008-07, Vol.3 (7), p.e2681-e2681

2008

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Dual Requirement for Gephyrin in Glycine Receptor Clustering and Molybdoenzyme Activity

Science (American Association for the Advancement of Science), 1998-11, Vol.282 (5392), p.1321-1324

1998

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Kinetic and mutational analysis of Zn2+ modulation of recombinant human inhibitory glycine receptors

The Journal of physiology, 2000-01, Vol.522 (2), p.215-230

2000

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Components of the Translational Machinery Are Associated with Juvenile Glycine Receptors and Are Redistributed to the Cytoskeleton upon Aging and Synaptic Activity

The Journal of biological chemistry, 2007-12, Vol.282 (52), p.37783-37793

2007

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Structure and Functions of Inhibitory and Excitatory Glycine Receptors

Annals of the New York Academy of Sciences, 1999-04, Vol.868 (1), p.667-676

1999

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Biphasic Alteration of the Inhibitory Synapse Scaffold Protein Gephyrin in Early and Late Stages of an Alzheimer Disease Model

The American journal of pathology, 2016-09, Vol.186 (9), p.2279-2291

2016

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Artemisinin-treatment in pre-symptomatic APP-PS1 mice increases gephyrin phosphorylation at Ser270: a modification regulating postsynaptic GABA A R density

Biological chemistry, 2022-01, Vol.403 (1), p.73

2022

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Effects of two elongation factor 1A isoforms on the formation of gephyrin clusters at inhibitory synapses in hippocampal neurons

Histochemistry and cell biology, 2013-12, Vol.140 (6), p.603-609

2013

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Amyloid-β Fosters p35/CDK5 Signaling Contributing to Changes of Inhibitory Synapses in Early Stages of Cerebral Amyloidosis

Journal of Alzheimer's disease, 2020-01, Vol.74 (4), p.1167

2020

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Targeting of Glycine Receptor Subunits to Gephyrin-Rich Domains in Transfected Human Embryonic Kidney Cells

Molecular and cellular neuroscience, 1995-10, Vol.6 (5), p.450-461

1995

Volltextzugriff (PDF)

Artesunate restores the levels of inhibitory synapse proteins and reduces amyloid-β and C-terminal fragments (CTFs) of the amyloid precursor protein in an AD-mouse model

Molecular and cellular neuroscience, 2021-06, Vol.113, p.103624-103624, Article 103624

2021

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Phosphorylation of Gephyrin in Hippocampal Neurons by Cyclin-dependent Kinase CDK5 at Ser-270 Is Dependent on Collybistin

The Journal of biological chemistry, 2012-09, Vol.287 (37), p.30952-30966

2012

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A Novel Domain of the Inhibitory Glycine Receptor Determining Antagonist Efficacies: Further Evidence for Partial Agonism Resulting from Self-Inhibition

Molecular pharmacology, 1999-09, Vol.56 (3), p.464-472

1999

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Expression and Initial Characterization of a Soluble Glycine Binding Domain of the N-Methyl-d-aspartate Receptor NR1 Subunit

The Journal of biological chemistry, 1998-08, Vol.273 (32), p.19933-19937

1998

Volltextzugriff (PDF)

Point mutation of glycine receptor α1 subunit in the spasmodic mouse affects agonist responses

FEBS letters, 1994-08, Vol.350 (1), p.71-76

1994

Volltextzugriff (PDF)

Effects of distinct collybistin isoforms on the formation of GABAergic synapses in hippocampal neurons

Molecular and cellular neuroscience, 2012-07, Vol.50 (3-4), p.250-259

2012

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Early alterations in hippocampal perisomatic GABAergic synapses and network oscillations in a mouse model of Alzheimer's disease amyloidosis

Loss of Extrasynaptic Inhibitory Glycine Receptors in the Hippocampus of an AD Mouse Model Is Restored by Treatment with Artesunate

Binding of gephyrin to microtubules is regulated by its phosphorylation at Ser270

Gephyrin: a key regulatory protein of inhibitory synapses and beyond

Another Use for a Proven Drug: Experimental Evidence for the Potential of Artemisinin and Its Derivatives to Treat Alzheimer's Disease

Cyclin-dependent kinase 5 is involved in the phosphorylation of gephyrin and clustering of GABAA receptors at inhibitory synapses of hippocampal neurons

Evidence for a Tetrameric Structure of Recombinant NMDA Receptors

KCC2 knockdown impairs glycinergic synapse maturation in cultured spinal cord neurons

Molecular Determinants of Agonist Discrimination by NMDA Receptor Subunits: Analysis of the Glutamate Binding Site on the NR2B Subunit

Activity-dependent shedding of the NMDA receptor glycine binding site by matrix metalloproteinase 3: a PUTATIVE mechanism of postsynaptic plasticity

Dual Requirement for Gephyrin in Glycine Receptor Clustering and Molybdoenzyme Activity

Kinetic and mutational analysis of Zn2+ modulation of recombinant human inhibitory glycine receptors

Components of the Translational Machinery Are Associated with Juvenile Glycine Receptors and Are Redistributed to the Cytoskeleton upon Aging and Synaptic Activity

Structure and Functions of Inhibitory and Excitatory Glycine Receptors

Biphasic Alteration of the Inhibitory Synapse Scaffold Protein Gephyrin in Early and Late Stages of an Alzheimer Disease Model

Artemisinin-treatment in pre-symptomatic APP-PS1 mice increases gephyrin phosphorylation at Ser270: a modification regulating postsynaptic GABA A R density

Effects of two elongation factor 1A isoforms on the formation of gephyrin clusters at inhibitory synapses in hippocampal neurons

Amyloid-β Fosters p35/CDK5 Signaling Contributing to Changes of Inhibitory Synapses in Early Stages of Cerebral Amyloidosis

Targeting of Glycine Receptor Subunits to Gephyrin-Rich Domains in Transfected Human Embryonic Kidney Cells

Artesunate restores the levels of inhibitory synapse proteins and reduces amyloid-β and C-terminal fragments (CTFs) of the amyloid precursor protein in an AD-mouse model

Phosphorylation of Gephyrin in Hippocampal Neurons by Cyclin-dependent Kinase CDK5 at Ser-270 Is Dependent on Collybistin

A Novel Domain of the Inhibitory Glycine Receptor Determining Antagonist Efficacies: Further Evidence for Partial Agonism Resulting from Self-Inhibition

Expression and Initial Characterization of a Soluble Glycine Binding Domain of the N-Methyl-d-aspartate Receptor NR1 Subunit

Point mutation of glycine receptor α1 subunit in the spasmodic mouse affects agonist responses

Effects of distinct collybistin isoforms on the formation of GABAergic synapses in hippocampal neurons

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