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Targeting Chemokine Receptors in HIV : A Status Report

Annual review of pharmacology and toxicology, 2008-01, Vol.48 (1), p.425-461

2008

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HIV-1 clones resistant to a small molecule CCR5 inhibitor use the inhibitor-bound form of CCR5 for entry

Virology (New York, N.Y.), 2007-04, Vol.361 (1), p.212-228

2007

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Generation and properties of a human immunodeficiency virus type 1 isolate resistant to the small molecule CCR5 inhibitor, SCH-417690 (SCH-D)

Virology (New York, N.Y.), 2005-07, Vol.338 (1), p.182-199

2005

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Genetic and Phenotypic Analyses of Human Immunodeficiency Virus Type 1 Escape from a Small-Molecule CCR5 Inhibitor

Journal of Virology, 2004-03, Vol.78 (6), p.2790-2807

2004

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HIV-1 Escape from a Small Molecule, CCR5-Specific Entry Inhibitor Does Not Involve CXCR4 Use

Proceedings of the National Academy of Sciences - PNAS, 2002-01, Vol.99 (1), p.395-400

2002

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Escape of HIV-1 from a small molecule CCR5 inhibitor is not associated with a fitness loss

PLoS pathogens, 2007-06, Vol.3 (6), p.e79-e79

2007

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The prolonged culture of human immunodeficiency virus type 1 in primary lymphocytes increases its sensitivity to neutralization by soluble CD4

Virology (New York, N.Y.), 2004-03, Vol.321 (1), p.8-22

2004

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Effects of CCR5 and CD4 Cell Surface Concentrations on Infections by Macrophagetropic Isolates of Human Immunodeficiency Virus Type 1

Journal of Virology, 1998-04, Vol.72 (4), p.2855-2864

1998

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The Differential Sensitivity of Human and Rhesus Macaque CCR5 to Small-Molecule Inhibitors of Human Immunodeficiency Virus Type 1 Entry Is Explained by a Single Amino Acid Difference and Suggests a Mechanism of Action for These Inhibitors

Journal of Virology, 2004-04, Vol.78 (8), p.4134-4144

2004

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Cooperation of Multiple CCR5 Coreceptors Is Required for Infections by Human Immunodeficiency Virus Type 1

Journal of Virology, 2000-08, Vol.74 (15), p.7005-7015

2000

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Interaction of small molecule inhibitors of HIV-1 entry with CCR5

Virology (New York, N.Y.), 2006-05, Vol.349 (1), p.41-54

2006

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Use of a small molecule CCR5 inhibitor in macaques to treat simian immunodeficiency virus infection or prevent simian-human immunodeficiency virus infection

The Journal of experimental medicine, 2003-11, Vol.198 (10), p.1551-1562

2003

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Cell surface expression of CCR5 and other host factors influence the inhibition of HIV-1 infection of human lymphocytes by CCR5 ligands

Virology (New York, N.Y.), 2007-08, Vol.364 (2), p.281-290

2007

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Adaptive Mutations in the V3 Loop of gp120 Enhance Fusogenicity of Human Immunodeficiency Virus Type 1 and Enable Use of a CCR5 Coreceptor That Lacks the Amino-Terminal Sulfated Region

Journal of Virology, 2001-12, Vol.75 (24), p.12266-12278

2001

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A Critical Site in the Core of the CCR5 Chemokine Receptor Required for Binding and Infectivity of Human Immunodeficiency Virus Type 1

The Journal of biological chemistry, 1999-01, Vol.274 (4), p.1905-1913

1999

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HIV-1 entry inhibitor entrances

Trends in pharmacological sciences (Regular ed.), 2004-03, Vol.25 (3), p.117-120

2004

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Frequent Substitution Polymorphisms in African Green Monkey CCR5 Cluster at Critical Sites for Infections by Simian Immunodeficiency Virus SIVagm, Implying Ancient Virus-Host Coevolution

Journal of Virology, 2001-09, Vol.75 (18), p.8449-8460

2001

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Roles of CD4 and Coreceptors in Binding, Endocytosis, and Proteolysis of gp120 Envelope Glycoproteins Derived from Human Immunodeficiency Virus Type 1

The Journal of biological chemistry, 1999-08, Vol.274 (33), p.23499-23507

1999

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Polymorphisms in the CCR5 genes of African green monkeys and mice implicate specific amino acids in infections by simian and human immunodeficiency viruses

Journal of Virology, 1997-11, Vol.71 (11), p.8642-8656

1997

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The Fitness Cost to Human Immunodeficiency Virus Type 1 of Escaping From a Small Molecule CCR5 Inhibitor

Retrovirology, 2005-12, Vol.2 (S1), p.S9-S9, Article S9

2005

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Modulation of ecotropic murine retroviruses by N-linked glycosylation of the cell surface receptor/amino acid transporter

Journal of Virology, 1996-10, Vol.70 (10), p.6884-6891

1996

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Genetic and Phenotypic Analyses of Human Immunodeficiency Virus Type 1 Escape from a Small-Molecule CCR5 Inhibitor

Journal of virology, 2004-06, Vol.78 (12), p.6706-6706

2004

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Targeting Chemokine Receptors in HIV : A Status Report

HIV-1 clones resistant to a small molecule CCR5 inhibitor use the inhibitor-bound form of CCR5 for entry

Generation and properties of a human immunodeficiency virus type 1 isolate resistant to the small molecule CCR5 inhibitor, SCH-417690 (SCH-D)

Genetic and Phenotypic Analyses of Human Immunodeficiency Virus Type 1 Escape from a Small-Molecule CCR5 Inhibitor

HIV-1 Escape from a Small Molecule, CCR5-Specific Entry Inhibitor Does Not Involve CXCR4 Use

Escape of HIV-1 from a small molecule CCR5 inhibitor is not associated with a fitness loss

The prolonged culture of human immunodeficiency virus type 1 in primary lymphocytes increases its sensitivity to neutralization by soluble CD4

Effects of CCR5 and CD4 Cell Surface Concentrations on Infections by Macrophagetropic Isolates of Human Immunodeficiency Virus Type 1

The Differential Sensitivity of Human and Rhesus Macaque CCR5 to Small-Molecule Inhibitors of Human Immunodeficiency Virus Type 1 Entry Is Explained by a Single Amino Acid Difference and Suggests a Mechanism of Action for These Inhibitors

Cooperation of Multiple CCR5 Coreceptors Is Required for Infections by Human Immunodeficiency Virus Type 1

Interaction of small molecule inhibitors of HIV-1 entry with CCR5

Use of a small molecule CCR5 inhibitor in macaques to treat simian immunodeficiency virus infection or prevent simian-human immunodeficiency virus infection

Cell surface expression of CCR5 and other host factors influence the inhibition of HIV-1 infection of human lymphocytes by CCR5 ligands

Adaptive Mutations in the V3 Loop of gp120 Enhance Fusogenicity of Human Immunodeficiency Virus Type 1 and Enable Use of a CCR5 Coreceptor That Lacks the Amino-Terminal Sulfated Region

A Critical Site in the Core of the CCR5 Chemokine Receptor Required for Binding and Infectivity of Human Immunodeficiency Virus Type 1

HIV-1 entry inhibitor entrances

Frequent Substitution Polymorphisms in African Green Monkey CCR5 Cluster at Critical Sites for Infections by Simian Immunodeficiency Virus SIVagm, Implying Ancient Virus-Host Coevolution

Roles of CD4 and Coreceptors in Binding, Endocytosis, and Proteolysis of gp120 Envelope Glycoproteins Derived from Human Immunodeficiency Virus Type 1

Polymorphisms in the CCR5 genes of African green monkeys and mice implicate specific amino acids in infections by simian and human immunodeficiency viruses

The Fitness Cost to Human Immunodeficiency Virus Type 1 of Escaping From a Small Molecule CCR5 Inhibitor

Modulation of ecotropic murine retroviruses by N-linked glycosylation of the cell surface receptor/amino acid transporter

Genetic and Phenotypic Analyses of Human Immunodeficiency Virus Type 1 Escape from a Small-Molecule CCR5 Inhibitor

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