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AMP-activated protein kinase and human cancer: cancer metabolism revisited

International Journal of Obesity, 2008-09, Vol.32 (S4), p.S36-S41

Kuhajda, F.P

2008

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Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology

Nutrition, 2000-03, Vol.16 (3), p.202-208

Kuhajda, Francis P

2000

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Malonyl-CoA decarboxylase inhibition is selectively cytotoxic to human breast cancer cells

Oncogene, 2009-08, Vol.28 (33), p.2979-2987

2009

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Reduced Food Intake and Body Weight in Mice Treated with Fatty Acid Synthase Inhibitors

Science (American Association for the Advancement of Science), 2000-06, Vol.288 (5475), p.2379-2381

2000

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Synthesis and Antitumor Activity of an Inhibitor of Fatty Acid Synthase

Proceedings of the National Academy of Sciences - PNAS, 2000-03, Vol.97 (7), p.3450-3454

2000

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Enzymes of the fatty acid synthesis pathway are highly expressed in in situ breast carcinoma

Clinical cancer research, 1997-11, Vol.3 (11), p.2115-2120

1997

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Elevated expression of fatty acid synthase and fatty acid synthetic activity in colorectal neoplasia

The American journal of pathology, 1997-01, Vol.150 (1), p.201-208

1997

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Fatty Acid Synthesis: A Potential Selective Target for Antineoplastic Therapy

Proceedings of the National Academy of Sciences - PNAS, 1994-07, Vol.91 (14), p.6379-6383

1994

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Inhibition of fatty acid synthesis induces programmed cell death in human breast cancer cells

Cancer research (Chicago, Ill.), 1996-06, Vol.56 (12), p.2745-2747

1996

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Inhibition of fatty acid synthesis delays disease progression in a xenograft model of ovarian cancer

Cancer research (Chicago, Ill.), 1996-03, Vol.56 (6), p.1189-1193

1996

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Fatty acid synthase expression in endometrial carcinoma: Correlation with cell proliferation and hormone receptors

Cancer, 1998-08, Vol.83 (3), p.528-537

1998

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C75, a Fatty Acid Synthase Inhibitor, Reduces Food Intake via Hypothalamic AMP-activated Protein Kinase

The Journal of biological chemistry, 2004-05, Vol.279 (19), p.19970-19976

2004

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Positive feedback regulation between AKT activation and fatty acid synthase expression in ovarian carcinoma cells

Oncogene, 2005-05, Vol.24 (22), p.3574-3582

2005

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Fatty acid synthase inhibitors are chemopreventive for mammary cancer in neu-N transgenic mice

Oncogene, 2005-01, Vol.24 (1), p.39-46

2005

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Malonyl-coenzyme-A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenografts

Cancer research (Chicago, Ill.), 2000-01, Vol.60 (2), p.213-218

2000

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Fatty acid synthase (FAS) : a target for cytotoxic antimetabolites in HL60 promyelocytic leukemia cells

Cancer research (Chicago, Ill.), 1996-02, Vol.56 (4), p.745-751

1996

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Fatty Acid Synthase Inhibition in Human Breast Cancer Cells Leads to Malonyl-CoA-Induced Inhibition of Fatty Acid Oxidation and Cytotoxicity

Biochemical and biophysical research communications, 2001-07, Vol.285 (2), p.217-223

2001

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Identification, purification, and partial characterization of a novel Mr 28,000 integral membrane protein from erythrocytes and renal tubules

The Journal of biological chemistry, 1988-10, Vol.263 (30), p.15634-15642

1988

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Novel nuclear phosphoprotein pp32 is highly expressed in intermediate- and high-grade prostate cancer

The Prostate, 1998-02, Vol.34 (3), p.231-237

1998

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C75, a Fatty Acid Synthase Inhibitor, Modulates AMP-activated Protein Kinase to Alter Neuronal Energy Metabolism

The Journal of biological chemistry, 2004-01, Vol.279 (5), p.3817-3827

2004

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Application of a Flexible Synthesis of (5R)-Thiolactomycin To Develop New Inhibitors of Type I Fatty Acid Synthase

Journal of medicinal chemistry, 2005-02, Vol.48 (4), p.946-961

2005

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Fatty acid synthase and cancer : New application of an old pathway

Cancer research (Chicago, Ill.), 2006-06, Vol.66 (12), p.5977-5980

KUHAJDA, Francis P

2006

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Antimycobacterial activity of cerulenin and its effects on lipid biosynthesis

Journal of antimicrobial chemotherapy, 1999-02, Vol.43 (2), p.219-226

1999

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Structure of pp32, an acidic nuclear protein which inhibits oncogene-induced formation of transformed foci

Molecular biology of the cell, 1996-12, Vol.7 (12), p.2045-2056

1996

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Increased Fatty Acid Synthase is a Therapeutic Target in Mesothelioma

Clinical cancer research, 2001-01, Vol.7 (1), p.153-157

2001

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AMP-activated protein kinase and human cancer: cancer metabolism revisited

Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology

Malonyl-CoA decarboxylase inhibition is selectively cytotoxic to human breast cancer cells

Reduced Food Intake and Body Weight in Mice Treated with Fatty Acid Synthase Inhibitors

Synthesis and Antitumor Activity of an Inhibitor of Fatty Acid Synthase

Enzymes of the fatty acid synthesis pathway are highly expressed in in situ breast carcinoma

Elevated expression of fatty acid synthase and fatty acid synthetic activity in colorectal neoplasia

Fatty Acid Synthesis: A Potential Selective Target for Antineoplastic Therapy

Inhibition of fatty acid synthesis induces programmed cell death in human breast cancer cells

Inhibition of fatty acid synthesis delays disease progression in a xenograft model of ovarian cancer

Fatty acid synthase expression in endometrial carcinoma: Correlation with cell proliferation and hormone receptors

C75, a Fatty Acid Synthase Inhibitor, Reduces Food Intake via Hypothalamic AMP-activated Protein Kinase

Positive feedback regulation between AKT activation and fatty acid synthase expression in ovarian carcinoma cells

Fatty acid synthase inhibitors are chemopreventive for mammary cancer in neu-N transgenic mice

Malonyl-coenzyme-A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenografts

Fatty acid synthase (FAS) : a target for cytotoxic antimetabolites in HL60 promyelocytic leukemia cells

Fatty Acid Synthase Inhibition in Human Breast Cancer Cells Leads to Malonyl-CoA-Induced Inhibition of Fatty Acid Oxidation and Cytotoxicity

Identification, purification, and partial characterization of a novel Mr 28,000 integral membrane protein from erythrocytes and renal tubules

Novel nuclear phosphoprotein pp32 is highly expressed in intermediate- and high-grade prostate cancer

C75, a Fatty Acid Synthase Inhibitor, Modulates AMP-activated Protein Kinase to Alter Neuronal Energy Metabolism

Application of a Flexible Synthesis of (5R)-Thiolactomycin To Develop New Inhibitors of Type I Fatty Acid Synthase

Fatty acid synthase and cancer : New application of an old pathway

Antimycobacterial activity of cerulenin and its effects on lipid biosynthesis

Structure of pp32, an acidic nuclear protein which inhibits oncogene-induced formation of transformed foci

Increased Fatty Acid Synthase is a Therapeutic Target in Mesothelioma

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