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Relationship between Drug Release of DE-310, Macromolecular Prodrug of DX-8951f, and Cathepsins Activity in Several Tumors

Biological and Pharmaceutical Bulletin, 2007/12/01, Vol.30(12), pp.2365-2370

2007

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Systematic Research of Peptide Spacers Controlling Drug Release from Macromolecular Prodrug System, Carboxymethyldextran Polyalcohol−Peptide−Drug Conjugates

Bioconjugate chemistry, 2009-01, Vol.20 (1), p.60-70

2009

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Pharmacokinetics of trastuzumab deruxtecan (T-DXd), a novel anti-HER2 antibody-drug conjugate, in HER2-positive tumour-bearing mice

Xenobiotica, 2020-10, Vol.50 (10), p.1242-1250

2020

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Quantitative acid hydrolysis of DE-310, a macromolecular carrier system for the camptothecin analog DX-8951f

Journal of pharmaceutical and biomedical analysis, 2007-03, Vol.43 (4), p.1290-1296

2007

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A possible mechanism for the long-lasting antitumor effect of the macromolecular conjugate DE-310: mediation by cellular uptake and drug release of its active camptothecin analog DX-8951

Cancer chemotherapy and pharmacology, 2005-04, Vol.55 (4), p.323-332

2005

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In vivo inhibition of acylpeptide hydrolase by carbapenem antibiotics causes the decrease of plasma concentration of valproic acid in dogs

Xenobiotica, 2016-02, Vol.46 (2), p.126-131

2016

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Observation of Clinically Relevant Drug Interaction in Chimeric Mice with Humanized Livers: The Case of Valproic Acid and Carbapenem Antibiotics

European journal of drug metabolism and pharmacokinetics, 2017-12, Vol.42 (6), p.965-972

2017

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DX‐8951F, a water‐soluble camptothecin analog, exhibits potent antitumor activity against a human lung cancer cell line and its SN‐38‐resistant variant

International journal of cancer, 1997-08, Vol.72 (4), p.680-686

1997

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Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11

Cancer research (Chicago, Ill.), 1991-08, Vol.51 (16), p.4187-4191

1991

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Structural study on a sulfated polysaccharide-peptidoglycan complex produced by Arthrobacter sp

Bioscience, biotechnology, and biochemistry, 1998-11, Vol.62 (11), p.2138-2144

1998

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CM-dextran-polyalcohol-camptothecin conjugate: DE-310 with a novel carrier system and its preclinical data

Advances in experimental medicine and biology, 2003, Vol.519, p.145

2003

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Hyperthermia-enhanced tumor accumulation and antitumor efficacy of a doxorubicin-conjugate with a novel macromolecular carrier system in mice with non-small cell lung cancer

Oncology reports, 2007-03, Vol.17 (3), p.653-659

2007

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Isolation and Characterization of Cytotoxic Compounds from Corn

Bioscience, biotechnology, and biochemistry, 1993, Vol.57 (6), p.1020-1021

1993

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CLOSTOMICINS, NEW ANTIBIOTICS PRODUCED BY MICROMONOSPORA ECHINOSPORA SUBSP. ARMENIACA SUBSP. NOV: I. PRODUCTION, ISOLATION, AND PHYSICO-CHEMICAL AND BIOLOGICAL PROPERTIES

The Journal of Antibiotics, 1986, Vol.39(10), pp.1407-1412

1986

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Adecypenol, a unique adenosine deaminase inhibitor containing homopurine and cyclopentene rings

Journal of antibiotics, 1986, Vol.39 (2), p.309-310

1986

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Structures of jietacines: Unique .ALPHA.,.BETA.-unsaturated azoxy antibiotics

Journal of antibiotics, 1989, Vol.42 (1), p.156-158

1989

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ADECHLORIN, A NEW ADENOSINE DEAMINASE INHIBITOR CONTAINING CHLORINE PRODUCTION, ISOLATION AND PROPERTIES

The Journal of Antibiotics, 1985, Vol.38(8), pp.1008-1015

1985

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ADECYPENOL, A UNIQUE ADENOSINE DEAMINASE INHIBITOR CONTAINING HOMOPURINE AND CYCLOPENTENE RINGS: TAXONOMY, PRODUCTION AND ENZYME INHIBITION

The Journal of Antibiotics, 1986, Vol.39(9), pp.1219-1224

1986

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Stimulation of all T cells bearing V beta 1, V beta 3, V beta 11 and V beta 12 by staphylococcal enterotoxin A

European journal of immunology, 1990-03, Vol.20 (3), p.617-621

1990

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Antitumor activities of ketol forms of unsaturated fatty acids from a water extract of corn grain

Nippon Nōgeikagaku Kaishi, 1993/10/01, Vol.67(10), pp.1411-1416

1993

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Stimulation of all T cells bearing Vβ1, Vβ3, Vβ11 and Vβ12 by staphylococcal enterotoxin A

European journal of immunology, 1990-03, Vol.20 (3), p.617-621

1990

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Structural studies on a sulfated polysaccharide from an Arthrobacter sp. by NMR spectroscopy and methylation analysis

Carbohydrate research, 1997-12, Vol.305 (2), p.253-260

1997

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Inhibitory Activity of Camptothecin Derivatives Against Acetylcholinesterase in Dogs and Their Binding Activity to Acetylcholine Receptors in Rats

Journal of pharmacy and pharmacology, 1993-05, Vol.45 (5), p.444-448

1993

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Camptothecin analog (CPT-11)-sensitive human pancreatic tumor cell line QGP-1N shows resistance to SN-38, an active metabolite of CPT-11

Biochemical and biophysical research communications, 1992-10, Vol.188 (1), p.70-77

1992

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Antihypertensive action of 3,4-dihydro-8-(2-hydroxy-3-isopropylamino) propoxy-3-nitroxy-2H-1-benzopyran (K-351) in hypertensive rats

Japanese journal of pharmacology, 1982, Vol.32, p.135-135

1982

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Relationship between Drug Release of DE-310, Macromolecular Prodrug of DX-8951f, and Cathepsins Activity in Several Tumors

Systematic Research of Peptide Spacers Controlling Drug Release from Macromolecular Prodrug System, Carboxymethyldextran Polyalcohol−Peptide−Drug Conjugates

Pharmacokinetics of trastuzumab deruxtecan (T-DXd), a novel anti-HER2 antibody-drug conjugate, in HER2-positive tumour-bearing mice

Quantitative acid hydrolysis of DE-310, a macromolecular carrier system for the camptothecin analog DX-8951f

A possible mechanism for the long-lasting antitumor effect of the macromolecular conjugate DE-310: mediation by cellular uptake and drug release of its active camptothecin analog DX-8951

In vivo inhibition of acylpeptide hydrolase by carbapenem antibiotics causes the decrease of plasma concentration of valproic acid in dogs

Observation of Clinically Relevant Drug Interaction in Chimeric Mice with Humanized Livers: The Case of Valproic Acid and Carbapenem Antibiotics

DX‐8951F, a water‐soluble camptothecin analog, exhibits potent antitumor activity against a human lung cancer cell line and its SN‐38‐resistant variant

Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11

Structural study on a sulfated polysaccharide-peptidoglycan complex produced by Arthrobacter sp

CM-dextran-polyalcohol-camptothecin conjugate: DE-310 with a novel carrier system and its preclinical data

Hyperthermia-enhanced tumor accumulation and antitumor efficacy of a doxorubicin-conjugate with a novel macromolecular carrier system in mice with non-small cell lung cancer

Isolation and Characterization of Cytotoxic Compounds from Corn

CLOSTOMICINS, NEW ANTIBIOTICS PRODUCED BY MICROMONOSPORA ECHINOSPORA SUBSP. ARMENIACA SUBSP. NOV: I. PRODUCTION, ISOLATION, AND PHYSICO-CHEMICAL AND BIOLOGICAL PROPERTIES

Adecypenol, a unique adenosine deaminase inhibitor containing homopurine and cyclopentene rings

Structures of jietacines: Unique .ALPHA.,.BETA.-unsaturated azoxy antibiotics

ADECHLORIN, A NEW ADENOSINE DEAMINASE INHIBITOR CONTAINING CHLORINE PRODUCTION, ISOLATION AND PROPERTIES

ADECYPENOL, A UNIQUE ADENOSINE DEAMINASE INHIBITOR CONTAINING HOMOPURINE AND CYCLOPENTENE RINGS: TAXONOMY, PRODUCTION AND ENZYME INHIBITION

Stimulation of all T cells bearing V beta 1, V beta 3, V beta 11 and V beta 12 by staphylococcal enterotoxin A

Antitumor activities of ketol forms of unsaturated fatty acids from a water extract of corn grain

Stimulation of all T cells bearing Vβ1, Vβ3, Vβ11 and Vβ12 by staphylococcal enterotoxin A

Structural studies on a sulfated polysaccharide from an Arthrobacter sp. by NMR spectroscopy and methylation analysis

Inhibitory Activity of Camptothecin Derivatives Against Acetylcholinesterase in Dogs and Their Binding Activity to Acetylcholine Receptors in Rats

Camptothecin analog (CPT-11)-sensitive human pancreatic tumor cell line QGP-1N shows resistance to SN-38, an active metabolite of CPT-11

Antihypertensive action of 3,4-dihydro-8-(2-hydroxy-3-isopropylamino) propoxy-3-nitroxy-2H-1-benzopyran (K-351) in hypertensive rats

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