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Chemical and structural biology of protein lysine deacetylases

Proceedings of the Japan Academy, Series B, 2017/05/11, Vol.93(5), pp.297-321

2017

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Identification of a novel small molecule that inhibits deacetylase but not defatty-acylase reaction catalysed by SIRT2

Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2018-06, Vol.373 (1748), p.20170070

2018

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Biocompatibility and therapeutic potential of glycosylated albumin artificial metalloenzymes

Nature catalysis, 2019-09, Vol.2 (9), p.780-792

2019

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Kinetic and Structural Basis for Acyl-Group Selectivity and NAD+ Dependence in Sirtuin-Catalyzed Deacylation

Biochemistry (Easton), 2015-05, Vol.54 (19), p.3037-3050

2015

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A novel GSK3 inhibitor that promotes self-renewal in mouse embryonic stem cells

Bioscience, biotechnology, and biochemistry, 2020-10, Vol.84 (10), p.2113-2120

2020

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Structural basis for specific lipid recognition by CERT responsible for nonvesicular trafficking of ceramide

Proceedings of the National Academy of Sciences - PNAS, 2008-01, Vol.105 (2), p.488-493

2008

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Discovery of Benzylpiperazine Derivatives as CNS-Penetrant and Selective Histone Deacetylase 6 Inhibitors

ACS medicinal chemistry letters, 2022-07, Vol.13 (7), p.1077-1082

2022

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Opening the Selectivity Pocket in the Human Lysine Deacetylase Sirtuin2 – New Opportunities, New Questions

Chemical record, 2018-12, Vol.18 (12), p.1701-1707

2018

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Halistanol sulfates I and J, new SIRT1–3 inhibitory steroid sulfates from a marine sponge of the genus Halichondria

Journal of antibiotics, 2018-02, Vol.71 (2), p.273-278

2018

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Adaptive evolution of fish hatching enzyme: one amino acid substitution results in differential salt dependency of the enzyme

Journal of experimental biology, 2013-05, Vol.216 (Pt 9), p.1609-1615

2013

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Design, Synthesis and Structure-Activity Relationship Study of Pyrilamine Derivatives as Histone Deacetylase Inhibitors

Heterocycles, 2020, Vol.101 (2), p.726

2020

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Runx3 controls the axonal projection of proprioceptive dorsal root ganglion neurons

Nature neuroscience, 2002-10, Vol.5 (10), p.946-954

2002

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Basis of Changes in Left-Right Coordination of Rhythmic Motor Activity during Development in the Rat Spinal Cord

The Journal of neuroscience, 2002-12, Vol.22 (23), p.10388-10398

2002

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Formation of the central pattern generator for locomotion in the rat and mouse

Brain research bulletin, 2000-11, Vol.53 (5), p.661-669

2000

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Structure of the histone chaperone CIA/ASF1-double bromodomain complex linking histone modifications and site-specific histone eviction

Proceedings of the National Academy of Sciences - PNAS, 2010-05, Vol.107 (18), p.8153-8158

2010

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Three-Dimensional Solution Structure of Oryzacystatin-I, a Cysteine Proteinase Inhibitor of the Rice, Oryza sativa L. japonica

Biochemistry (Easton), 2000-12, Vol.39 (48), p.14753-14760

2000

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Crystal Structures of the Short-Chain Flavin Reductase HpaC from Sulfolobus tokodaii Strain 7 in Its Three States: NAD(P)+-Free, NAD+-Bound, and NADP+-Bound

Biochemistry (Easton), 2006-04, Vol.45 (16), p.5103-5110

2006

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5-Hydroxytryptamine-induced locomotor rhythm in the neonatal mouse spinal cord in vitro

Neuroscience letters, 2000-02, Vol.280 (3), p.187-190

2000

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Rhythmic Motor Activity in Thin Transverse Slice Preparations of the Fetal Rat Spinal Cord

Journal of neurophysiology, 2004-07, Vol.92 (1), p.648-652

2004

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Peripheral targets influence sensory-motor connectivity in the neonatal spinal cord: Sciatic nerve axotomy in Bax-deficient mice

Neuroscience research, 2006, Vol.54 (1), p.30-37

2006

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Crystal Structures of the CERT START Domain with Inhibitors Provide Insights into the Mechanism of Ceramide Transfer

Journal of molecular biology, 2010-02, Vol.396 (2), p.245-251

2010

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Rostrocaudal Progression in the Development of Periodic Spontaneous Activity in Fetal Rat Spinal Motor Circuits In Vitro

Journal of neurophysiology, 1999-05, Vol.81 (5), p.2592-2595

1999

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Crystallization and preliminary X-ray analysis of HCE-1, a hatching enzyme of medaka fish, Oryzias latipes

Acta crystallographica. Section D, Biological crystallography., 2004-04, Vol.60 (4), p.725-726

2004

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The effects of sciatic nerve axotomy on spinal motoneurons in neonatal Bax-deficient mice

Neuroscience research, 2002-12, Vol.44 (4), p.439-446

2002

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Beam diagnostics for high quality electron beam emitted from photocathode rf-gun

Journal of physics. Conference series, 2006-03, Vol.31 (1), p.229-230

2006

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Chemical and structural biology of protein lysine deacetylases

Identification of a novel small molecule that inhibits deacetylase but not defatty-acylase reaction catalysed by SIRT2

Biocompatibility and therapeutic potential of glycosylated albumin artificial metalloenzymes

Kinetic and Structural Basis for Acyl-Group Selectivity and NAD+ Dependence in Sirtuin-Catalyzed Deacylation

A novel GSK3 inhibitor that promotes self-renewal in mouse embryonic stem cells

Structural basis for specific lipid recognition by CERT responsible for nonvesicular trafficking of ceramide

Discovery of Benzylpiperazine Derivatives as CNS-Penetrant and Selective Histone Deacetylase 6 Inhibitors

Opening the Selectivity Pocket in the Human Lysine Deacetylase Sirtuin2 – New Opportunities, New Questions

Halistanol sulfates I and J, new SIRT1–3 inhibitory steroid sulfates from a marine sponge of the genus Halichondria

Adaptive evolution of fish hatching enzyme: one amino acid substitution results in differential salt dependency of the enzyme

Design, Synthesis and Structure-Activity Relationship Study of Pyrilamine Derivatives as Histone Deacetylase Inhibitors

Runx3 controls the axonal projection of proprioceptive dorsal root ganglion neurons

Basis of Changes in Left-Right Coordination of Rhythmic Motor Activity during Development in the Rat Spinal Cord

Formation of the central pattern generator for locomotion in the rat and mouse

Structure of the histone chaperone CIA/ASF1-double bromodomain complex linking histone modifications and site-specific histone eviction

Three-Dimensional Solution Structure of Oryzacystatin-I, a Cysteine Proteinase Inhibitor of the Rice, Oryza sativa L. japonica

Crystal Structures of the Short-Chain Flavin Reductase HpaC from Sulfolobus tokodaii Strain 7 in Its Three States: NAD(P)+-Free, NAD+-Bound, and NADP+-Bound

5-Hydroxytryptamine-induced locomotor rhythm in the neonatal mouse spinal cord in vitro

Rhythmic Motor Activity in Thin Transverse Slice Preparations of the Fetal Rat Spinal Cord

Peripheral targets influence sensory-motor connectivity in the neonatal spinal cord: Sciatic nerve axotomy in Bax-deficient mice

Crystal Structures of the CERT START Domain with Inhibitors Provide Insights into the Mechanism of Ceramide Transfer

Rostrocaudal Progression in the Development of Periodic Spontaneous Activity in Fetal Rat Spinal Motor Circuits In Vitro

Crystallization and preliminary X-ray analysis of HCE-1, a hatching enzyme of medaka fish, Oryzias latipes

The effects of sciatic nerve axotomy on spinal motoneurons in neonatal Bax-deficient mice

Beam diagnostics for high quality electron beam emitted from photocathode rf-gun

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