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A Compendium of Mutational Signatures of Environmental Agents

Cell, 2019-05, Vol.177 (4), p.821-836.e16

2019

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Cell cycle alterations induced by urban PM2.5 in bronchial epithelial cells: characterization of the process and possible mechanisms involved

Particle and fibre toxicology, 2013-12, Vol.10 (1), p.63-63

2013

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The genome as a record of environmental exposure

Mutagenesis, 2015-11, Vol.30 (6), p.763-770

2015

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Metabolic Activation of Benzo[ a ]pyrene by Human Tissue Organoid Cultures

International journal of molecular sciences, 2022-12, Vol.24 (1), p.606

2022

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Nutlin‐3a selects for cells harbouring TP53 mutations

International journal of cancer, 2017-02, Vol.140 (4), p.877-887

2017

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Carcinogenic polycyclic aromatic hydrocarbons induce CYP1A1 in human cells via a p53-dependent mechanism

Archives of toxicology, 2016-02, Vol.90 (2), p.291-304

2016

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Tissue Organoid Cultures Metabolize Dietary Carcinogens Proficiently and Are Effective Models for DNA Adduct Formation

Chemical research in toxicology, 2024-02, Vol.37 (2), p.234-247

2024

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Linking environmental carcinogen exposure to TP53 mutations in human tumours using the human TP53 knock-in (Hupki) mouse model

The FEBS journal, 2010-06, Vol.277 (12), p.2567-2583

2010

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Mutagenicity of acrylamide and glycidamide in human TP53 knock-in (Hupki) mouse embryo fibroblasts

Archives of toxicology, 2020-12, Vol.94 (12), p.4173-4196

2020

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Akt phosphorylates the Y-box binding protein 1 at Ser102 located in the cold shock domain and affects the anchorage-independent growth of breast cancer cells

Oncogene, 2005-06, Vol.24 (26), p.4281-4292

2005

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Mutagenicity of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N–OH-PhIP) in human TP53 knock-in (Hupki) mouse embryo fibroblasts

Food and chemical toxicology, 2021-01, Vol.147, p.111855, Article 111855

2021

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Mutagenicity of N‐hydroxy‐4‐aminobiphenyl in human TP53 knock‐in (Hupki) mouse embryo fibroblasts

Environmental and molecular mutagenesis, 2021-04, Vol.62 (4), p.252-264

2021

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Evidence of exposure to aristolochic acid in patients with urothelial cancer from a Balkan endemic nephropathy region of Romania

Environmental and molecular mutagenesis, 2012-10, Vol.53 (8), p.636-641

2012

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TP53 and lacZ mutagenesis induced by 3-nitrobenzanthrone in Xpa-deficient human TP53 knock-in mouse embryo fibroblasts

DNA repair, 2016-03, Vol.39, p.21-33

2016

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Preferential dependence of breast cancer cells versus normal cells on integrin-linked kinase for protein kinase B/Akt activation and cell survival

Cancer research (Chicago, Ill.), 2006, Vol.66 (1), p.393-403

2006

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Celecoxib analogues disrupt Akt signaling, which is commonly activated in primary breast tumours

Breast cancer research : BCR, 2005-01, Vol.7 (5), p.R796-R807, Article R796

2005

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Comparison of the metabolic activation of environmental carcinogens in mouse embryonic stem cells and mouse embryonic fibroblasts

Toxicology in vitro, 2015-02, Vol.29 (1), p.34-43

2015

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Metabolic activation of diesel exhaust carcinogens in primary and immortalized human TP53 knock-in (Hupki) mouse embryo fibroblasts

Environmental and molecular mutagenesis, 2012-04, Vol.53 (3), p.207-217

2012

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Characterising Mutational Spectra of Carcinogens in the Tumour Suppressor Gene TP53 Using Human TP53 Knock-in (Hupki) Mouse Embryo Fibroblasts

Methods and protocols, 2019-11, Vol.2 (4), p.85

2019

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Expression of the insulin-like growth factor I receptor and urokinase plasminogen activator in breast Cancer is associated with poor survival: Potential for intervention with 17-allylamino geldanamycin

Cancer research (Chicago, Ill.), 2004, Vol.64 (1), p.286-291

2004

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Nutlin‐3a selects for cells harbouring TP 53 mutations

International journal of cancer, 2017-02, Vol.140 (4), p.877-887

2017

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Next Generation Sequencing Workshop at the Royal Society of Medicine (London, May 2022): how genomics is on the path to modernizing genetic toxicology

Mutagenesis, 2023-08, Vol.38 (4), p.192-200

2023

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Celecoxib inhibits urokinase-type plasminogen activator (uPA) production in MDA-MB-231 breast cancer cells

Breast cancer research and treatment, 2005-11, Vol.94 (1), p.47-52

2005

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Role of IGF-1R in Mediating Breast Cancer Invasion and Metastasis

Breast disease, 2003, Vol.17 (1), p.41-47

2003

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TP53 mutations induced by BPDE in Xpa-WT and Xpa-Null human TP53 knock-in (Hupki) mouse embryo fibroblasts

Mutation research, 2015-03, Vol.773, p.48-62

2015

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A Compendium of Mutational Signatures of Environmental Agents

Cell cycle alterations induced by urban PM2.5 in bronchial epithelial cells: characterization of the process and possible mechanisms involved

The genome as a record of environmental exposure

Metabolic Activation of Benzo[ a ]pyrene by Human Tissue Organoid Cultures

Nutlin‐3a selects for cells harbouring TP53 mutations

Carcinogenic polycyclic aromatic hydrocarbons induce CYP1A1 in human cells via a p53-dependent mechanism

Tissue Organoid Cultures Metabolize Dietary Carcinogens Proficiently and Are Effective Models for DNA Adduct Formation

Linking environmental carcinogen exposure to TP53 mutations in human tumours using the human TP53 knock-in (Hupki) mouse model

Mutagenicity of acrylamide and glycidamide in human TP53 knock-in (Hupki) mouse embryo fibroblasts

Akt phosphorylates the Y-box binding protein 1 at Ser102 located in the cold shock domain and affects the anchorage-independent growth of breast cancer cells

Mutagenicity of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N–OH-PhIP) in human TP53 knock-in (Hupki) mouse embryo fibroblasts

Mutagenicity of N‐hydroxy‐4‐aminobiphenyl in human TP53 knock‐in (Hupki) mouse embryo fibroblasts

Evidence of exposure to aristolochic acid in patients with urothelial cancer from a Balkan endemic nephropathy region of Romania

TP53 and lacZ mutagenesis induced by 3-nitrobenzanthrone in Xpa-deficient human TP53 knock-in mouse embryo fibroblasts

Preferential dependence of breast cancer cells versus normal cells on integrin-linked kinase for protein kinase B/Akt activation and cell survival

Celecoxib analogues disrupt Akt signaling, which is commonly activated in primary breast tumours

Comparison of the metabolic activation of environmental carcinogens in mouse embryonic stem cells and mouse embryonic fibroblasts

Metabolic activation of diesel exhaust carcinogens in primary and immortalized human TP53 knock-in (Hupki) mouse embryo fibroblasts

Characterising Mutational Spectra of Carcinogens in the Tumour Suppressor Gene TP53 Using Human TP53 Knock-in (Hupki) Mouse Embryo Fibroblasts

Expression of the insulin-like growth factor I receptor and urokinase plasminogen activator in breast Cancer is associated with poor survival: Potential for intervention with 17-allylamino geldanamycin

Nutlin‐3a selects for cells harbouring TP 53 mutations

Next Generation Sequencing Workshop at the Royal Society of Medicine (London, May 2022): how genomics is on the path to modernizing genetic toxicology

Celecoxib inhibits urokinase-type plasminogen activator (uPA) production in MDA-MB-231 breast cancer cells

Role of IGF-1R in Mediating Breast Cancer Invasion and Metastasis

TP53 mutations induced by BPDE in Xpa-WT and Xpa-Null human TP53 knock-in (Hupki) mouse embryo fibroblasts

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