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Plasma Dihydroceramides Are Diabetes Susceptibility Biomarker Candidates in Mice and Humans

Cell reports (Cambridge), 2017-02, Vol.18 (9), p.2269-2279

2017

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Mitochondrial Reactive Oxygen Species Are Obligatory Signals for Glucose-Induced Insulin Secretion

Diabetes (New York, N.Y.), 2009-03, Vol.58 (3), p.673-681

2009

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Mitochondrial Reactive Oxygen Species Are Required for Hypothalamic Glucose Sensing

Diabetes (New York, N.Y.), 2006-07, Vol.55 (7), p.2084-2090

2006

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Small molecule glucokinase activators disturb lipid homeostasis and induce fatty liver in rodents: a warning for therapeutic applications in humans

British journal of pharmacology, 2013-01, Vol.168 (2), p.339-353

2013

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Insulinotropic agent ID-1101 (4-hydroxyisoleucine) activates insulin signaling in rat

American journal of physiology: endocrinology and metabolism, 2004-09, Vol.287 (3), p.E463-E471

2004

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Exploring functional beta-cell heterogeneity in vivo using PSA-NCAM as a specific marker

PloS one, 2009-05, Vol.4 (5), p.e5555-e5555

2009

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Psammomys Obesus, a Model for Environment-Gene Interactions in Type 2 Diabetes

Diabetes (New York, N.Y.), 2005-12, Vol.54 (suppl 2), p.S137-S144

2005

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Fatty Acid Signaling in the Hypothalamus and the Neural Control of Insulin Secretion

Diabetes (New York, N.Y.), 2006-12, Vol.55 (Supplement 2), p.S139-S144

2006

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Pathophysiological, genetic and gene expression features of a novel rodent model of the cardio-metabolic syndrome

PloS one, 2008-08, Vol.3 (8), p.e2962-e2962

2008

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Lipid environment induces ER stress, TXNIP expression and inflammation in immune cells of individuals with type 2 diabetes

Diabetologia, 2018-02, Vol.61 (2), p.399-412

2018

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Design and Synthesis of Imidazoline Derivatives Active on Glucose Homeostasis in a Rat Model of Type II Diabetes. 1. Synthesis and Biological Activities of N-Benzyl-N ‘-(arylalkyl)-2-(4‘,5‘-dihydro-1‘H-imidazol-2‘-yl)piperazines

Journal of medicinal chemistry, 1997-11, Vol.40 (23), p.3793-3803

1997

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Endocrine pancreas plasticity under physiological and pathological conditions

Diabetes (New York, N.Y.), 2001-02, Vol.50 (suppl 1), p.S30-S35

2001

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Coordinate Transcriptomic and Metabolomic Effects of the Insulin Sensitizer Rosiglitazone on Fundamental Metabolic Pathways in Liver, Soleus Muscle, and Adipose Tissue in Diabetic db/db Mice

PPAR Research, 2010-01, Vol.2010 (2010), p.472-488

2010

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Structure–Activity Relationship of Azaindole-Based Glucokinase Activators

Journal of medicinal chemistry, 2016-01, Vol.59 (2), p.687-706

2016

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Anti-diabetic activity of fused PPARγ-SIRT1 ligands with limited body-weight gain by mimicking calorie restriction and decreasing SGK1 expression

European journal of medicinal chemistry, 2017-09, Vol.137, p.310-326

2017

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Proteasomal degradation of retinoid X receptor α reprograms transcriptional activity of PPARγ in obese mice and humans

The Journal of clinical investigation, 2010-05, Vol.120 (5), p.1454-1468

2010

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Specific and Combined Effects of Insulin and Glucose on Functional Pancreatic β-Cell Mass in Vivo in Adult Rats

Endocrinology (Philadelphia), 2003-06, Vol.144 (6), p.2717-2727

2003

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Dynamic Changes in β-Cell Mass and Pancreatic Insulin During the Evolution of Nutrition-Dependent Diabetes in Psammomys obesus

Diabetes (New York, N.Y.), 2005-01, Vol.54 (1), p.138-145

2005

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Synthesis of a Novel Series of 8-HETE Analogs and their Biological Evaluation Towards the PPAR Nuclear Receptors

Letters in drug design & discovery, 2008-12, Vol.5 (8), p.503-511

2008

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The Use of Functional MRI to Study Appetite Control in the CNS

Experimental diabetes research, 2012-01, Vol.2012 (2012), p.1-13

2012

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Interaction entre facteurs d’environnement et fonds génétique dans le diabète de type 2: L’apport des modèles animaux

M.S. Médecine sciences, 2013-08, Vol.29 (8-9), p.791-799

2013

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Interaction between environment and genetic background in type 2 diabetes: lessons from animal models

M.S. Médecine sciences, 2013-08, Vol.29 (8-9), p.791

2013

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Coadministration of Coenzyme Q prevents Rosiglitazone-induced adipogenesis in ob/ob mice

International Journal of Obesity, 2009-02, Vol.33 (2), p.204-211

2009

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Plasma Dihydroceramides Are Diabetes Susceptibility Biomarker Candidates in Mice and Humans

Mitochondrial Reactive Oxygen Species Are Obligatory Signals for Glucose-Induced Insulin Secretion

Mitochondrial Reactive Oxygen Species Are Required for Hypothalamic Glucose Sensing

Small molecule glucokinase activators disturb lipid homeostasis and induce fatty liver in rodents: a warning for therapeutic applications in humans

Interleukin-7 regulates adipose tissue mass and insulin sensitivity in high-fat diet-fed mice through lymphocyte-dependent and independent mechanisms

Insulinotropic agent ID-1101 (4-hydroxyisoleucine) activates insulin signaling in rat

Exploring functional beta-cell heterogeneity in vivo using PSA-NCAM as a specific marker

Psammomys Obesus, a Model for Environment-Gene Interactions in Type 2 Diabetes

Fatty Acid Signaling in the Hypothalamus and the Neural Control of Insulin Secretion

Pathophysiological, genetic and gene expression features of a novel rodent model of the cardio-metabolic syndrome

Lipid environment induces ER stress, TXNIP expression and inflammation in immune cells of individuals with type 2 diabetes

Design and Synthesis of Imidazoline Derivatives Active on Glucose Homeostasis in a Rat Model of Type II Diabetes. 1. Synthesis and Biological Activities of N-Benzyl-N ‘-(arylalkyl)-2-(4‘,5‘-dihydro-1‘H-imidazol-2‘-yl)piperazines

Endocrine pancreas plasticity under physiological and pathological conditions

Coordinate Transcriptomic and Metabolomic Effects of the Insulin Sensitizer Rosiglitazone on Fundamental Metabolic Pathways in Liver, Soleus Muscle, and Adipose Tissue in Diabetic db/db Mice

Structure–Activity Relationship of Azaindole-Based Glucokinase Activators

Anti-diabetic activity of fused PPARγ-SIRT1 ligands with limited body-weight gain by mimicking calorie restriction and decreasing SGK1 expression

Proteasomal degradation of retinoid X receptor α reprograms transcriptional activity of PPARγ in obese mice and humans

Specific and Combined Effects of Insulin and Glucose on Functional Pancreatic β-Cell Mass in Vivo in Adult Rats

Dynamic Changes in β-Cell Mass and Pancreatic Insulin During the Evolution of Nutrition-Dependent Diabetes in Psammomys obesus

Synthesis of a Novel Series of 8-HETE Analogs and their Biological Evaluation Towards the PPAR Nuclear Receptors

The Use of Functional MRI to Study Appetite Control in the CNS

Interaction entre facteurs d’environnement et fonds génétique dans le diabète de type 2: L’apport des modèles animaux

Interaction between environment and genetic background in type 2 diabetes: lessons from animal models

Molecular phenotyping of multiple mouse strains under metabolic challenge uncovers a role for Elovl2 in glucose-induced insulin secretion

Coadministration of Coenzyme Q prevents Rosiglitazone-induced adipogenesis in ob/ob mice

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