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JLK1486, a N,N-[(8-hydroxyquinoline)methyl]-substituted benzylamine analogue, inhibits melanoma proliferation and induces autophagy

Cell proliferation, 2014-10, Vol.47 (5), p.416-426

2014

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New N4-substituted piperazine naphthamide derivatives as BACE-1 inhibitors

Journal of enzyme inhibition and medicinal chemistry, 2009-02, Vol.24 (1), p.181-187

2009

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Prospects for the resistance to HIV protease inhibitors: current drug design approaches and perspectives

Current pharmaceutical design, 2005-09, Vol.11 (24), p.3077-3090

2005

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New 3‘-Azido-3‘-deoxythymidin-5‘-yl O-(4-Hydroxyalkyl or -Alkenyl or -Alkylepoxide) Carbonate Prodrugs: Synthesis and Anti-HIV Evaluation

Journal of medicinal chemistry, 2001-08, Vol.44 (18), p.3014-3021

2001

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New 3‘-Azido-3‘-deoxythymidin-5‘-yl O-(ω-Hydroxyalkyl) Carbonate Prodrugs: Synthesis and Anti-HIV Evaluation

Journal of medicinal chemistry, 2001-03, Vol.44 (5), p.777-786

2001

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Anti-human immunodeficiency virus type 1 activity and in vitro toxicity of 2'-deoxy-3'-thiacytidine (BCH-189), a novel heterocyclic nucleoside analog

Antimicrobial Agents and Chemotherapy, 1991-07, Vol.35 (7), p.1386-1390

1991

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New Bicyclam−AZT Conjugates: Design, Synthesis, Anti-HIV Evaluation, and Their Interaction with CXCR-4 Coreceptor

Journal of medicinal chemistry, 1999-01, Vol.42 (2), p.229-241

1999

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use of proline bioisosteres in potential HIV protease inhibitors: phenylalanine-2-thiophenoxy-3-pyrrolidinone: synthesis and anti-HIV evaluation

Bioorganic & medicinal chemistry letters, 2000-09, Vol.10 (17), p.2023-2026

2000

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Design and evaluation of hepatitis B virus inhibitors

Current pharmaceutical design, 2000-03, Vol.6 (5), p.503-523

2000

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BACE-1 inhibitory activities of new substituted phenyl-piperazine coupled to various heterocycles: Chromene, coumarin and quinoline

Bioorganic & medicinal chemistry letters, 2006-04, Vol.16 (7), p.1995-1999

2006

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New anti-HIV derivatives : Synthesis and antiviral evaluation

Bioorganic & medicinal chemistry, 2000-06, Vol.8 (6), p.1253-1262

2000

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Synthesis of New Covalently Bound κ-Carrageenan−AZT Conjugates with Improved Anti-HIV Activities

Journal of medicinal chemistry, 2002-03, Vol.45 (6), p.1275-1283

2002

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Selective inhibition of the duck hepatitis B virus by a new class of tetraazamacrocycles

Antimicrobial Agents and Chemotherapy, 1997-11, Vol.41 (11), p.2579-2581

1997

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New antiviral nucleoside prodrugs await application

Current medicinal chemistry, 2003-09, Vol.10 (18), p.1825-1843

2003

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Novel cyclized Pifithrin-α p53 inactivators: synthesis and biological studies

Bioorganic & medicinal chemistry letters, 2005-03, Vol.15 (6), p.1561-1564

2005

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Synthesis and anti-HIV activity of α-thiophenoxy-hydroxyethylamide derivatives

European journal of medicinal chemistry, 1999-07, Vol.34 (7), p.625-638

1999

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Syntheses of new modified Phe-Pro peptides. Use of proline replacements in potential HIV inhibitors

Bioorganic & medicinal chemistry letters, 1998-02, Vol.8 (3), p.277-280

1998

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Inhibition of Human Immunodeficiency Virus Type 1 Replication by Phosphonoformate- and Phosphonoacetate-2',3'-Dideoxy-3'-thiacytidine Conjugates

Journal of medicinal chemistry, 1994-07, Vol.37 (14), p.2216-2223

1994

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Synthesis and biological activity of N-substituted spiro[benzoxazepine-piperidine] Aβ-peptide production inhibitors

Journal of enzyme inhibition and medicinal chemistry, 2008, Vol.23 (6), p.996-1001

2008

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Enhanced delivery of gamma-secretase inhibitor DAPT into the brain via an ascorbic acid mediated strategy

Organic & biomolecular chemistry, 2005-07, Vol.3 (13), p.2450-2457

2005

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Synthesis and anti-HIV activities of symmetrical N1,N3-dibenzyl-2-hydroxy-propane derivatives

Bioorganic & medicinal chemistry letters, 1998-07, Vol.8 (14), p.1861-1866

1998

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Design, synthesis and structure relationships of new N,N',N,N'-tetrakis (ω-amino alkyl) tetraazamacrocycles

Antiviral chemistry & chemotherapy, 1998, Vol.9 (1), p.73-84

1998

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Substituted thiazolamide coupled to a redox delivery system: a new gamma-secretase inhibitor with enhanced pharmacokinetic profile

Organic & biomolecular chemistry, 2005-02, Vol.3 (4), p.612-618

2005

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Synthesis and Antiviral Activity of New Anti-HIV Amprenavir Bioisosteres

Journal of medicinal chemistry, 2002-07, Vol.45 (15), p.3321-3324

2002

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Synthesis of New Tetrakis N-Substituted Tetra-Azamacrocycles

Synthetic communications, 1998-01, Vol.28 (2), p.311-317

1998

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JLK1486, a N,N-[(8-hydroxyquinoline)methyl]-substituted benzylamine analogue, inhibits melanoma proliferation and induces autophagy

New N4-substituted piperazine naphthamide derivatives as BACE-1 inhibitors

Prospects for the resistance to HIV protease inhibitors: current drug design approaches and perspectives

New 3‘-Azido-3‘-deoxythymidin-5‘-yl O-(4-Hydroxyalkyl or -Alkenyl or -Alkylepoxide) Carbonate Prodrugs: Synthesis and Anti-HIV Evaluation

New 3‘-Azido-3‘-deoxythymidin-5‘-yl O-(ω-Hydroxyalkyl) Carbonate Prodrugs: Synthesis and Anti-HIV Evaluation

Anti-human immunodeficiency virus type 1 activity and in vitro toxicity of 2'-deoxy-3'-thiacytidine (BCH-189), a novel heterocyclic nucleoside analog

New Bicyclam−AZT Conjugates: Design, Synthesis, Anti-HIV Evaluation, and Their Interaction with CXCR-4 Coreceptor

use of proline bioisosteres in potential HIV protease inhibitors: phenylalanine-2-thiophenoxy-3-pyrrolidinone: synthesis and anti-HIV evaluation

Design and evaluation of hepatitis B virus inhibitors

BACE-1 inhibitory activities of new substituted phenyl-piperazine coupled to various heterocycles: Chromene, coumarin and quinoline

New anti-HIV derivatives : Synthesis and antiviral evaluation

Synthesis of New Covalently Bound κ-Carrageenan−AZT Conjugates with Improved Anti-HIV Activities

Selective inhibition of the duck hepatitis B virus by a new class of tetraazamacrocycles

New antiviral nucleoside prodrugs await application

Novel cyclized Pifithrin-α p53 inactivators: synthesis and biological studies

Synthesis and anti-HIV activity of α-thiophenoxy-hydroxyethylamide derivatives

Syntheses of new modified Phe-Pro peptides. Use of proline replacements in potential HIV inhibitors

Inhibition of Human Immunodeficiency Virus Type 1 Replication by Phosphonoformate- and Phosphonoacetate-2',3'-Dideoxy-3'-thiacytidine Conjugates

Synthesis and biological activity of N-substituted spiro[benzoxazepine-piperidine] Aβ-peptide production inhibitors

Enhanced delivery of gamma-secretase inhibitor DAPT into the brain via an ascorbic acid mediated strategy

Synthesis and anti-HIV activities of symmetrical N1,N3-dibenzyl-2-hydroxy-propane derivatives

Design, synthesis and structure relationships of new N,N',N,N'-tetrakis (ω-amino alkyl) tetraazamacrocycles

Substituted thiazolamide coupled to a redox delivery system: a new gamma-secretase inhibitor with enhanced pharmacokinetic profile

Synthesis and Antiviral Activity of New Anti-HIV Amprenavir Bioisosteres

Synthesis of New Tetrakis N-Substituted Tetra-Azamacrocycles

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