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Acetylation of non-histone proteins modulates cellular signalling at multiple levels

The international journal of biochemistry & cell biology, 2009, Vol.41 (1), p.185-198

2009

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Drugging the HDAC6–HSP90 interplay in malignant cells

Trends in pharmacological sciences (Regular ed.), 2014-10, Vol.35 (10), p.501-509

2014

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HDAC2: a critical factor in health and disease

Trends in pharmacological sciences (Regular ed.), 2009-12, Vol.30 (12), p.647-655

Krämer, Oliver H

2009

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Concepts to Target MYC in Pancreatic Cancer

Molecular cancer therapeutics, 2016-08, Vol.15 (8), p.1792-1798

2016

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Interstrand Crosslink Repair as a Target for HDAC Inhibition

Trends in pharmacological sciences (Regular ed.), 2017-09, Vol.38 (9), p.822-836

2017

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Comparison of the antifibrotic effects of the pan-histone deacetylase-inhibitor panobinostat versus the IPF-drug pirfenidone in fibroblasts from patients with idiopathic pulmonary fibrosis

PloS one, 2018-11, Vol.13 (11), p.e0207915-e0207915

2018

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Histone deacetylase 2 controls p53 and is a critical factor in tumorigenesis

Biochimica et biophysica acta, 2014-12, Vol.1846 (2), p.524-538

2014

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Marbostat-100 Defines a New Class of Potent and Selective Antiinflammatory and Antirheumatic Histone Deacetylase 6 Inhibitors

Journal of medicinal chemistry, 2018-04, Vol.61 (8), p.3454-3477

2018

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Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRASG12C Inhibitor

Journal of medicinal chemistry, 2022-11, Vol.65 (21), p.14614-14629

2022

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HDAC1 and HDAC2 integrate checkpoint kinase phosphorylation and cell fate through the phosphatase-2A subunit PR130

Nature communications, 2018-02, Vol.9 (1), p.764-17, Article 764

2018

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The PP2A subunit PR130 is a key regulator of cell development and oncogenic transformation

Biochimica et biophysica acta. Reviews on cancer, 2020-12, Vol.1874 (2), p.188453, Article 188453

2020

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Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T‑Cell Prolymphocytic Leukemia

Journal of medicinal chemistry, 2021-06, Vol.64 (12), p.8486-8509

2021

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Survivin and YM155: How faithful is the liaison?

Biochimica et biophysica acta, 2014-04, Vol.1845 (2), p.202-220

2014

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The interplay between histone deacetylases and rho kinases is important for cancer and neurodegeneration

Cytokine & growth factor reviews, 2017-10, Vol.37, p.29-45

2017

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HDACi – Targets beyond chromatin

Cancer letters, 2009-08, Vol.280 (2), p.160-167

2009

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Phosphorylation–acetylation switch in the regulation of STAT1 signaling

Molecular and cellular endocrinology, 2010-02, Vol.315 (1), p.40-48

2010

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Chloroethylating nitrosoureas in cancer therapy: DNA damage, repair and cell death signaling

Biochimica et biophysica acta. Reviews on cancer, 2017-08, Vol.1868 (1), p.29-39

2017

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STAT1‑HDAC4 signaling induces epithelial‑mesenchymal transition and sphere formation of cancer cells overexpressing the oncogene, CUG2

Oncology reports, 2018-11, Vol.40 (5), p.2619-2627

2018

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Enhanced Histone Deacetylase Activity in Malignant Melanoma Provokes RAD51 and FANCD2-Triggered Drug Resistance

Cancer research (Chicago, Ill.), 2016-05, Vol.76 (10), p.3067-3077

2016

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Selective degradation of mutant FMS-like tyrosine kinase-3 requires BIM-dependent depletion of heat shock proteins

Leukemia, 2024-09

2024

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A phosphorylation-acetylation switch regulates STAT1 signaling

Genes & development, 2009-01, Vol.23 (2), p.223-235

2009

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Design and biological evaluation of tetrahydro-β-carboline derivatives as highly potent histone deacetylase 6 (HDAC6) inhibitors

European journal of medicinal chemistry, 2018-05, Vol.152, p.329-357

2018

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Histone deacetylase inhibitors modulate hormesis in leukemic cells with mutant FMS-like tyrosine kinase-3

Leukemia, 2023-11, Vol.37 (11), p.2319-2323

2023

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News and views: AUTOTACs join the arena for targeted protein degradation

Archives of toxicology, 2022-07, Vol.96 (7), p.2143-2144

2022

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NOXA Accentuates Apoptosis Induction by a Novel Histone Deacetylase Inhibitor

Cancers, 2023-07, Vol.15 (14), p.3650

2023

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Acetylation of non-histone proteins modulates cellular signalling at multiple levels

Drugging the HDAC6–HSP90 interplay in malignant cells

HDAC2: a critical factor in health and disease

Concepts to Target MYC in Pancreatic Cancer

Interstrand Crosslink Repair as a Target for HDAC Inhibition

Comparison of the antifibrotic effects of the pan-histone deacetylase-inhibitor panobinostat versus the IPF-drug pirfenidone in fibroblasts from patients with idiopathic pulmonary fibrosis

Histone deacetylase 2 controls p53 and is a critical factor in tumorigenesis

Marbostat-100 Defines a New Class of Potent and Selective Antiinflammatory and Antirheumatic Histone Deacetylase 6 Inhibitors

Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRASG12C Inhibitor

HDAC1 and HDAC2 integrate checkpoint kinase phosphorylation and cell fate through the phosphatase-2A subunit PR130

The PP2A subunit PR130 is a key regulator of cell development and oncogenic transformation

Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T‑Cell Prolymphocytic Leukemia

Survivin and YM155: How faithful is the liaison?

The interplay between histone deacetylases and rho kinases is important for cancer and neurodegeneration

HDACi – Targets beyond chromatin

Phosphorylation–acetylation switch in the regulation of STAT1 signaling

Chloroethylating nitrosoureas in cancer therapy: DNA damage, repair and cell death signaling

STAT1‑HDAC4 signaling induces epithelial‑mesenchymal transition and sphere formation of cancer cells overexpressing the oncogene, CUG2

Enhanced Histone Deacetylase Activity in Malignant Melanoma Provokes RAD51 and FANCD2-Triggered Drug Resistance

Selective degradation of mutant FMS-like tyrosine kinase-3 requires BIM-dependent depletion of heat shock proteins

A phosphorylation-acetylation switch regulates STAT1 signaling

Design and biological evaluation of tetrahydro-β-carboline derivatives as highly potent histone deacetylase 6 (HDAC6) inhibitors

Histone deacetylase inhibitors modulate hormesis in leukemic cells with mutant FMS-like tyrosine kinase-3

News and views: AUTOTACs join the arena for targeted protein degradation

NOXA Accentuates Apoptosis Induction by a Novel Histone Deacetylase Inhibitor

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