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Antibody-maytansinoid conjugates are activated in targeted cancer cells by lysosomal degradation and linker-dependent intracellular processing
Cancer research (Chicago, Ill.), 2006-04, Vol.66 (8), p.4426-4433
2006
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Antibody-Maytansinoid Conjugates Designed to Bypass Multidrug Resistance
Cancer research (Chicago, Ill.), 2010-03, Vol.70 (6), p.2528-2537
2010
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High-affinity accumulation of a maytansinoid in cells via weak tubulin interaction
PloS one, 2015-02, Vol.10 (2), p.e0117523-e0117523
2015
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Cell killing by antibody–drug conjugates
Cancer letters, 2007-10, Vol.255 (2), p.232-240
2007
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Antibody-drug conjugates designed to eradicate tumors with homogeneous and heterogeneous expression of the target antigen
Cancer research (Chicago, Ill.), 2006-03, Vol.66 (6), p.3214-3221
2006
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A New Triglycyl Peptide Linker for Antibody-Drug Conjugates (ADCs) with Improved Targeted Killing of Cancer Cells
Molecular cancer therapeutics, 2016-06, Vol.15 (6), p.1311-1320
2016
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Antibody-drug conjugates: using monoclonal antibodies for delivery of cytotoxic payloads to cancer cells
Therapeutic delivery, 2011-03, Vol.2 (3), p.397-416
2011
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Peptide-Cleavable Self-immolative Maytansinoid Antibody–Drug Conjugates Designed To Provide Improved Bystander Killing
ACS medicinal chemistry letters, 2019-10, Vol.10 (10), p.1393-1399
2019
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Peptide-Cleavable Self-immolative Maytansinoid Antibody–Drug Conjugates Designed To Provide Improved Bystander Killing
ACS medicinal chemistry letters, 2019-10, Vol.10 (10), p.1393-1399
2019
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Antibody–Drug Conjugates for Targeted Cancer Therapy
Annual Reports in Medicinal Chemistry, 2012, Vol.47, p.349-366
2012
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A new middle repetitive sequence of Nicotiana plumbaginifolia genome
Plant molecular biology, 1993-10, Vol.23 (2), p.435-438
1993
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Cognition and comorbidity in postmenopausal women
BIO Web of Conferences, 2020, Vol.22, p.1023
2020
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Synthesis and Evaluation of Hydrophilic Linkers for Antibody–Maytansinoid Conjugates
Journal of medicinal chemistry, 2011-05, Vol.54 (10), p.3606-3623
2011
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Disulfide-Linked Antibody−Maytansinoid Conjugates: Optimization of In Vivo Activity by Varying the Steric Hindrance at Carbon Atoms Adjacent to the Disulfide Linkage
Bioconjugate chemistry, 2011-04, Vol.22 (4), p.717-727
2011
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A DNA-Interacting Payload Designed to Eliminate Cross-Linking Improves the Therapeutic Index of Antibody-Drug Conjugates (ADCs)
Molecular cancer therapeutics, 2018-03, Vol.17 (3), p.650-660
2018
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Pleiotropic Associations of Allelic Variants in a 2q22 Region with Risks of Major Human Diseases and Mortality
PLoS genetics, 2016-11, Vol.12 (11), p.e1006314-e1006314
2016
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A New Class of Antibody-Drug Conjugates with Potent DNA Alkylating Activity
Molecular cancer therapeutics, 2016-08, Vol.15 (8), p.1870-1878
2016
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Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases
Frontiers in genetics, 2016-10, Vol.7, p.179-179
2016
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A CD123-targeting antibody-drug conjugate, IMGN632, designed to eradicate AML while sparing normal bone marrow cells
Blood advances, 2018-04, Vol.2 (8), p.848-858
2018
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Semisynthetic Maytansine Analogues for the Targeted Treatment of Cancer
Journal of medicinal chemistry, 2006-07, Vol.49 (14), p.4392-4408
2006
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Abstract 2186: Peptide-cleavable maytansinoid (ADCs) induce high bystander killing leading to improved anti-tumor activity in vivo
Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.2186-2186
2017
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Development of Anilino-Maytansinoid ADCs that Efficiently Release Cytotoxic Metabolites in Cancer Cells and Induce High Levels of Bystander Killing
Bioconjugate chemistry, 2015-11, Vol.26 (11), p.2261-2278
2015
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Corrigendum: Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases
Frontiers in genetics, 2018-01, Vol.8, p.226-226
2018
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Adapting the Tuning Programme Profiles to the Needs of Russian Higher Education
Tuning Journal for Higher Education, 2014-04, Vol.1 (1), p.187-202
2014
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