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Into the Eye of the Cytokine Storm

Microbiology and Molecular Biology Reviews, 2012-03, Vol.76 (1), p.16-32

2012

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Host genetic diversity enables Ebola hemorrhagic fever pathogenesis and resistance

Science (American Association for the Advancement of Science), 2014-11, Vol.346 (6212), p.987-991

2014

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Lethal influenza virus infection in macaques is associated with early dysregulation of inflammatory related genes

PLoS pathogens, 2009-10, Vol.5 (10), p.e1000604-e1000604

2009

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Lassa antiviral LHF-535 protects guinea pigs from lethal challenge

Scientific reports, 2022-11, Vol.12 (1), p.19911-7, Article 19911

2022

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A potent Lassa virus antiviral targets an arenavirus virulence determinant

PLoS pathogens, 2018-12, Vol.14 (12), p.e1007439-e1007439

2018

Volltextzugriff (PDF)

Unique signatures of long noncoding RNA expression in response to virus infection and altered innate immune signaling

mBio, 2010-12, Vol.1 (5), p.e00206-e00206

2010

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Lethal Dissemination of H5N1 Influenza Virus Is Associated with Dysregulation of Inflammation and Lipoxin Signaling in a Mouse Model of Infection

Journal of Virology, 2010-08, Vol.84 (15), p.7613-7624

2010

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Pandemic Swine-Origin H1N1 Influenza A Virus Isolates Show Heterogeneous Virulence in Macaques

Journal of Virology, 2011-02, Vol.85 (3), p.1214-1223

2011

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A systems biology approach to infectious disease research: innovating the pathogen-host research paradigm

mBio, 2011-03, Vol.2 (1), p.e00325-e00310

2011

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Molecular Signatures Associated with Mx1-Mediated Resistance to Highly Pathogenic Influenza Virus Infection: Mechanisms of Survival

Journal of Virology, 2012-03, Vol.86 (5), p.2437-2446

2012

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Genomic Profiling of Tumor Necrosis Factor Alpha (TNF-α) Receptor and Interleukin-1 Receptor Knockout Mice Reveals a Link between TNF-α Signaling and Increased Severity of 1918 Pandemic Influenza Virus Infection

Journal of Virology, 2010-12, Vol.84 (24), p.12576-12588

2010

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Functional Genomics Reveals the Induction of Inflammatory Response and Metalloproteinase Gene Expression during Lethal Ebola Virus Infection

Journal of Virology, 2011-09, Vol.85 (17), p.9060-9068

2011

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Systems Virology Identifies a Mitochondrial Fatty Acid Oxidation Enzyme, Dodecenoyl Coenzyme A Delta Isomerase, Required for Hepatitis C Virus Replication and Likely Pathogenesis

Journal of Virology, 2011-11, Vol.85 (22), p.11646-11654

2011

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The NS1 Protein of the 1918 Pandemic Influenza Virus Blocks Host Interferon and Lipid Metabolism Pathways

Journal of Virology, 2009-10, Vol.83 (20), p.10557-10570

2009

Volltextzugriff (PDF)

Transcriptomic Analysis Reveals a Mechanism for a Prefibrotic Phenotype in STAT1 Knockout Mice during Severe Acute Respiratory Syndrome Coronavirus Infection

Journal of Virology, 2010-11, Vol.84 (21), p.11297-11309

2010

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NS1 protein of influenza A virus suppresses interferon-regulated activation of antigen-presentation and immune-proteasome pathways

Journal of general virology, 2011-09, Vol.92 (Pt 9), p.2093-2104

2011

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Viral Pathogenesis: From Basics to Systems Biology

3, 2016

Volltextzugriff (PDF)

Hepatitis C virus and liver disease: Global transcriptional profiling and identification of potential markers

Hepatology (Baltimore, Md.), 2003-12, Vol.38 (6), p.1458-1467, Article ajhep09024

2003

Volltextzugriff (PDF)

The Alpha/Beta Interferon Receptor Provides Protection against Influenza Virus Replication but Is Dispensable for Inflammatory Response Signaling

Journal of Virology, 2010-02, Vol.84 (4), p.2027-2037

2010

Volltextzugriff (PDF)

Genomic Analysis Reveals Pre- and Postchallenge Differences in a Rhesus Macaque AIDS Vaccine Trial: Insights into Mechanisms of Vaccine Efficacy

Journal of Virology, 2011-01, Vol.85 (2), p.1099-1116

2011

Volltextzugriff (PDF)

Chronic immune activation is a distinguishing feature of liver and PBMC gene signatures from HCV/HIV coinfected patients and may contribute to hepatic fibrogenesis

Virology (New York, N.Y.), 2012-08, Vol.430 (1), p.43-52

2012

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Drug repurposing: a better approach for infectious disease drug discovery?

Current opinion in immunology, 2013-10, Vol.25 (5), p.588-592

2013

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Systems virology: host-directed approaches to viral pathogenesis and drug targeting

Nature reviews. Microbiology, 2013-07, Vol.11 (7), p.455-466

2013

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Into the Eye of the Cytokine Storm

Host genetic diversity enables Ebola hemorrhagic fever pathogenesis and resistance

Lethal influenza virus infection in macaques is associated with early dysregulation of inflammatory related genes

Lassa antiviral LHF-535 protects guinea pigs from lethal challenge

A potent Lassa virus antiviral targets an arenavirus virulence determinant

Integrated Omics Analysis of Pathogenic Host Responses during Pandemic H1N1 Influenza Virus Infection: The Crucial Role of Lipid Metabolism

Unique signatures of long noncoding RNA expression in response to virus infection and altered innate immune signaling

Lethal Dissemination of H5N1 Influenza Virus Is Associated with Dysregulation of Inflammation and Lipoxin Signaling in a Mouse Model of Infection

Pandemic Swine-Origin H1N1 Influenza A Virus Isolates Show Heterogeneous Virulence in Macaques

A systems biology approach to infectious disease research: innovating the pathogen-host research paradigm

Molecular Signatures Associated with Mx1-Mediated Resistance to Highly Pathogenic Influenza Virus Infection: Mechanisms of Survival

Genomic Profiling of Tumor Necrosis Factor Alpha (TNF-α) Receptor and Interleukin-1 Receptor Knockout Mice Reveals a Link between TNF-α Signaling and Increased Severity of 1918 Pandemic Influenza Virus Infection

Functional Genomics Reveals the Induction of Inflammatory Response and Metalloproteinase Gene Expression during Lethal Ebola Virus Infection

Systems Virology Identifies a Mitochondrial Fatty Acid Oxidation Enzyme, Dodecenoyl Coenzyme A Delta Isomerase, Required for Hepatitis C Virus Replication and Likely Pathogenesis

The NS1 Protein of the 1918 Pandemic Influenza Virus Blocks Host Interferon and Lipid Metabolism Pathways

Transcriptomic Analysis Reveals a Mechanism for a Prefibrotic Phenotype in STAT1 Knockout Mice during Severe Acute Respiratory Syndrome Coronavirus Infection

Integrative deep sequencing of the mouse lung transcriptome reveals differential expression of diverse classes of small RNAs in response to respiratory virus infection

NS1 protein of influenza A virus suppresses interferon-regulated activation of antigen-presentation and immune-proteasome pathways

Viral Pathogenesis: From Basics to Systems Biology

Hepatitis C virus and liver disease: Global transcriptional profiling and identification of potential markers

The Alpha/Beta Interferon Receptor Provides Protection against Influenza Virus Replication but Is Dispensable for Inflammatory Response Signaling

Genomic Analysis Reveals Pre- and Postchallenge Differences in a Rhesus Macaque AIDS Vaccine Trial: Insights into Mechanisms of Vaccine Efficacy

Chronic immune activation is a distinguishing feature of liver and PBMC gene signatures from HCV/HIV coinfected patients and may contribute to hepatic fibrogenesis

Drug repurposing: a better approach for infectious disease drug discovery?

Systems virology: host-directed approaches to viral pathogenesis and drug targeting

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