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Dimerization leads to changes in APP (amyloid precursor protein) trafficking mediated by LRP1 and SorLA

Cellular and molecular life sciences : CMLS, 2018-01, Vol.75 (2), p.301-322

2018

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Amyloid Diseases: Abnormal Protein Aggregation in Neurodegeneration

Proceedings of the National Academy of Sciences - PNAS, 1999-08, Vol.96 (18), p.9989-9990

1999

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Evidence that production and release of amyloid beta-protein involves the endocytic pathway

The Journal of biological chemistry, 1994-07, Vol.269 (26), p.17386-17389

1994

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Evidence that β-Amyloid Protein in Alzheimer's Disease is not Derived by Normal Processing

Science (American Association for the Advancement of Science), 1990-04, Vol.248 (4954), p.492-495

1990

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Protein Phosphorylation Inhibits Production of Alzheimer Amyloid β/ A4 Peptide

Proceedings of the National Academy of Sciences - PNAS, 1993-10, Vol.90 (19), p.9195-9198

1993

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Pivotal role of the RanBP9-cofilin pathway in Aβ-induced apoptosis and neurodegeneration

Cell death and differentiation, 2012-09, Vol.19 (9), p.1413-1423

2012

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Targeting of cell-surface β-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments

Nature (London), 1992-06, Vol.357 (6378), p.500-503

1992

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Amyloid β-peptide is produced by cultured cells during normal metabolism

Nature (London), 1992-09, Vol.359 (6393), p.322-325

1992

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Potential role of presenilin-regulated signaling pathways in sporadic neurodegeneration

Nature medicine, 2004-07, Vol.10 Suppl (7), p.S26-S33

2004

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Amyloid β-Protein as a Substrate Interacts with Extracellular Matrix to Promote Neurite Outgrowth

Proceedings of the National Academy of Sciences - PNAS, 1993-05, Vol.90 (10), p.4748-4752

1993

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Identification and transport of full-length amyloid precursor proteins in rat peripheral nervous system

The Journal of neuroscience, 1993-07, Vol.13 (7), p.3136-3142

1993

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Aggregation of secreted amyloid beta-protein into sodium dodecyl sulfate-stable oligomers in cell culture

The Journal of biological chemistry, 1995-04, Vol.270 (16), p.9564-9570

1995

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Trafficking of Cell Surface β-Amyloid Precursor Protein: Retrograde and Transcytotic Transport in Cultured Neurons

The Journal of cell biology, 1995-04, Vol.129 (2), p.431-442

1995

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A subset of NSAIDs lower amyloidogenic A beta 42 independently of cyclooxygenase activity

Nature (London), 2001-11, Vol.414 (6860), p.212-216

2001

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Exchange of N-CoR Corepressor and Tip60 Coactivator Complexes Links Gene Expression by NF-κB and β-Amyloid Precursor Protein

Cell, 2002-07, Vol.110 (1), p.55-67

2002

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The Role of APP Processing and Trafficking Pathways in the Formation of Amyloid β-Protein

Annals of the New York Academy of Sciences, 1996-01, Vol.777 (1), p.57-64

1996

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Evidence that nonsteroidal anti-inflammatory drugs decrease amyloid beta 42 production by direct modulation of gamma-secretase activity

The Journal of biological chemistry, 2003-08, Vol.278 (34), p.31831-31837

2003

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Presenilin Couples the Paired Phosphorylation of β-Catenin Independent of Axin: Implications for β-Catenin Activation in Tumorigenesis

Cell, 2002-09, Vol.110 (6), p.751-762

2002

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Abeta induces cell death by direct interaction with its cognate extracellular domain on APP (APP 597-624)

The FASEB journal, 2006-06, Vol.20 (8), p.1254

2006

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Cell-surface beta-amyloid precursor protein stimulates neurite outgrowth of hippocampal neurons in an isoform-dependent manner

The Journal of neuroscience, 1995-03, Vol.15 (3), p.2157-2167

1995

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Polarized Secretion of β-Amyloid Precursor Protein and Amyloid β-Peptide in MDCK Cells

Proceedings of the National Academy of Sciences - PNAS, 1994-02, Vol.91 (4), p.1564-1568

1994

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A second cytotoxic proteolytic peptide derived from amyloid β-protein precursor

Nature medicine, 2000-04, Vol.6 (4), p.397-404

2000

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Precursor if Amyloid Protein in Alzheimer Disease Undergoes Fast Anterograde Axonal Transport

Proceedings of the National Academy of Sciences - PNAS, 1990-02, Vol.87 (4), p.1561-1565

1990

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Modulation of amyloid beta-protein clearance and Alzheimer's disease susceptibility by the LDL receptor-related protein pathway

The Journal of clinical investigation, 2000-11, Vol.106 (9), p.1159-1166

2000

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Potential link between amyloid beta-protein 42 and C-terminal fragment gamma 49-99 of beta-amyloid precursor protein

The Journal of biological chemistry, 2003-07, Vol.278 (27), p.24294-24301

2003

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Dimerization leads to changes in APP (amyloid precursor protein) trafficking mediated by LRP1 and SorLA

Amyloid Diseases: Abnormal Protein Aggregation in Neurodegeneration

Evidence that production and release of amyloid beta-protein involves the endocytic pathway

Evidence that β-Amyloid Protein in Alzheimer's Disease is not Derived by Normal Processing

Protein Phosphorylation Inhibits Production of Alzheimer Amyloid β/ A4 Peptide

Pivotal role of the RanBP9-cofilin pathway in Aβ-induced apoptosis and neurodegeneration

Targeting of cell-surface β-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments

Amyloid β-peptide is produced by cultured cells during normal metabolism

Potential role of presenilin-regulated signaling pathways in sporadic neurodegeneration

Amyloid β-Protein as a Substrate Interacts with Extracellular Matrix to Promote Neurite Outgrowth

Identification and transport of full-length amyloid precursor proteins in rat peripheral nervous system

Aggregation of secreted amyloid beta-protein into sodium dodecyl sulfate-stable oligomers in cell culture

Trafficking of Cell Surface β-Amyloid Precursor Protein: Retrograde and Transcytotic Transport in Cultured Neurons

A subset of NSAIDs lower amyloidogenic A beta 42 independently of cyclooxygenase activity

Exchange of N-CoR Corepressor and Tip60 Coactivator Complexes Links Gene Expression by NF-κB and β-Amyloid Precursor Protein

The Role of APP Processing and Trafficking Pathways in the Formation of Amyloid β-Protein

Evidence that nonsteroidal anti-inflammatory drugs decrease amyloid beta 42 production by direct modulation of gamma-secretase activity

Presenilin Couples the Paired Phosphorylation of β-Catenin Independent of Axin: Implications for β-Catenin Activation in Tumorigenesis

Abeta induces cell death by direct interaction with its cognate extracellular domain on APP (APP 597-624)

Cell-surface beta-amyloid precursor protein stimulates neurite outgrowth of hippocampal neurons in an isoform-dependent manner

Polarized Secretion of β-Amyloid Precursor Protein and Amyloid β-Peptide in MDCK Cells

A second cytotoxic proteolytic peptide derived from amyloid β-protein precursor

Precursor if Amyloid Protein in Alzheimer Disease Undergoes Fast Anterograde Axonal Transport

Modulation of amyloid beta-protein clearance and Alzheimer's disease susceptibility by the LDL receptor-related protein pathway

Potential link between amyloid beta-protein 42 and C-terminal fragment gamma 49-99 of beta-amyloid precursor protein

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