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MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition

PLoS biology, 2019-09, Vol.17 (9), p.e3000354-e3000354

2019

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The yeast proteases Ddi1 and Wss1 are both involved in the DNA replication stress response

DNA repair, 2019-08, Vol.80, p.45-51

2019

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Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors

European journal of medicinal chemistry, 2020-12, Vol.208, p.112754-112754, Article 112754

2020

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Structural and Thermodynamic Analysis of the Resistance Development to Pimodivir (VX-787), the Clinical Inhibitor of Cap Binding to PB2 Subunit of Influenza A Polymerase

Molecules (Basel, Switzerland), 2021-02, Vol.26 (4), p.1007

2021

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Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery

Journal of medicinal chemistry, 2021-05, Vol.64 (10), p.6706-6719

2021

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Structure of glutamate carboxypeptidase II, a drug target in neuronal damage and prostate cancer

The EMBO journal, 2006-03, Vol.25 (6), p.1375-1384

2006

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Malonate-based inhibitors of mammalian serine racemase: Kinetic characterization and structure-based computational study

European journal of medicinal chemistry, 2015-01, Vol.89, p.189-197

2015

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structural characterization of the interaction between the C-terminal domain of the influenza polymerase PA subunit and an optimized small peptide inhibitor

Antiviral research, 2021-01, Vol.185, p.104971, Article 104971

2021

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Synthesis and In Vitro Evaluation of C-7 and C-8 Luteolin Derivatives as Influenza Endonuclease Inhibitors

International journal of molecular sciences, 2021-07, Vol.22 (14), p.7735

2021

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Unorthodox inhibitors of HIV protease: looking beyond active-site-directed peptidomimetics

Current pharmaceutical design, 2014-01, Vol.20 (21), p.3389

2014

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Factors, associated with elevated concentration of soluble carbonic anhydrase IX in plasma of women with cervical dysplasia

Scientific reports, 2022-09, Vol.12 (1), p.15397-15397, Article 15397

2022

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From Nonpeptide toward Noncarbon Protease Inhibitors: Metallacarboranes as Specific and Potent Inhibitors of HIV Protease

Proceedings of the National Academy of Sciences - PNAS, 2005-10, Vol.102 (43), p.15394-15399

2005

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Specific Inhibitors of HIV Capsid Assembly Binding to the C‑Terminal Domain of the Capsid Protein: Evaluation of 2‑Arylquinazolines as Potential Antiviral Compounds

Journal of medicinal chemistry, 2016-01, Vol.59 (2), p.545-558

2016

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Design of HIV Protease Inhibitors Based on Inorganic Polyhedral Metallacarboranes

Journal of medicinal chemistry, 2009-11, Vol.52 (22), p.7132-7141

2009

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Human DNA-Damage-Inducible 2 Protein Is Structurally and Functionally Distinct from Its Yeast Ortholog

Scientific reports, 2016-07, Vol.6 (1), p.30443-30443, Article 30443

2016

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Current and Novel Inhibitors of HIV Protease

Viruses, 2009-12, Vol.1 (3), p.1209-1239

2009

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Triggering HIV polyprotein processing by light using rapid photodegradation of a tight-binding protease inhibitor

Nature communications, 2015-03, Vol.6 (1), p.6461-6461, Article 6461

2015

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Kinetic, Thermodynamic, and Structural Analysis of Drug Resistance Mutations in Neuraminidase from the 2009 Pandemic Influenza Virus

Viruses, 2018-06, Vol.10 (7), p.339

2018

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Correction: MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition

PLoS biology, 2019-10, Vol.17 (10), p.e3000529-e3000529

2019

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Viral proteases as therapeutic targets

Molecular aspects of medicine, 2022-12, Vol.88, p.101159-101159, Article 101159

2022

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Mouse glutamate carboxypeptidase II (GCPII) has a similar enzyme activity and inhibition profile but a different tissue distribution to human GCPII

FEBS open bio, 2017-09, Vol.7 (9), p.1362-1378

2017

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Structural Basis of Interactions between Human Glutamate Carboxypeptidase II and Its Substrate Analogs

Journal of molecular biology, 2008-03, Vol.376 (5), p.1438-1450

2008

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Molecular Analysis of the HIV-1 Resistance Development: Enzymatic Activities, Crystal Structures, and Thermodynamics of Nelfinavir-resistant HIV Protease Mutants

Journal of molecular biology, 2007-12, Vol.374 (4), p.1005-1016

2007

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A novel substrate-based HIV-1 protease inhibitor drug resistance mechanism

PLoS medicine, 2007-01, Vol.4 (1), p.e36-e36

2007

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Mutations in HIV-1 gag and pol Compensate for the Loss of Viral Fitness Caused by a Highly Mutated Protease

Antimicrobial Agents and Chemotherapy, 2012-08, Vol.56 (8), p.4320-4330

2012

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MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition

The yeast proteases Ddi1 and Wss1 are both involved in the DNA replication stress response

Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors

Structural and Thermodynamic Analysis of the Resistance Development to Pimodivir (VX-787), the Clinical Inhibitor of Cap Binding to PB2 Subunit of Influenza A Polymerase

Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery

Structure of glutamate carboxypeptidase II, a drug target in neuronal damage and prostate cancer

Malonate-based inhibitors of mammalian serine racemase: Kinetic characterization and structure-based computational study

structural characterization of the interaction between the C-terminal domain of the influenza polymerase PA subunit and an optimized small peptide inhibitor

Synthesis and In Vitro Evaluation of C-7 and C-8 Luteolin Derivatives as Influenza Endonuclease Inhibitors

Unorthodox inhibitors of HIV protease: looking beyond active-site-directed peptidomimetics

Factors, associated with elevated concentration of soluble carbonic anhydrase IX in plasma of women with cervical dysplasia

From Nonpeptide toward Noncarbon Protease Inhibitors: Metallacarboranes as Specific and Potent Inhibitors of HIV Protease

Specific Inhibitors of HIV Capsid Assembly Binding to the C‑Terminal Domain of the Capsid Protein: Evaluation of 2‑Arylquinazolines as Potential Antiviral Compounds

Design of HIV Protease Inhibitors Based on Inorganic Polyhedral Metallacarboranes

Human DNA-Damage-Inducible 2 Protein Is Structurally and Functionally Distinct from Its Yeast Ortholog

Current and Novel Inhibitors of HIV Protease

Triggering HIV polyprotein processing by light using rapid photodegradation of a tight-binding protease inhibitor

Kinetic, Thermodynamic, and Structural Analysis of Drug Resistance Mutations in Neuraminidase from the 2009 Pandemic Influenza Virus

Correction: MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition

Viral proteases as therapeutic targets

Mouse glutamate carboxypeptidase II (GCPII) has a similar enzyme activity and inhibition profile but a different tissue distribution to human GCPII

Structural Basis of Interactions between Human Glutamate Carboxypeptidase II and Its Substrate Analogs

Molecular Analysis of the HIV-1 Resistance Development: Enzymatic Activities, Crystal Structures, and Thermodynamics of Nelfinavir-resistant HIV Protease Mutants

A novel substrate-based HIV-1 protease inhibitor drug resistance mechanism

Mutations in HIV-1 gag and pol Compensate for the Loss of Viral Fitness Caused by a Highly Mutated Protease

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