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In vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2

Science (American Association for the Advancement of Science), 2004-02, Vol.303 (5659), p.844-848

2004

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Asymmetric Cyclopropanations by Rhodium(II) N-(Arylsulfonyl)prolinate Catalyzed Decomposition of Vinyldiazomethanes in the Presence of Alkenes. Practical Enantioselective Synthesis of the Four Stereoisomers of 2-Phenylcyclopropan-1-amino Acid

Journal of the American Chemical Society, 1996-07, Vol.118 (29), p.6897-6907

1996

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Study on High Availability and Fault Tolerance

2023 International Conference on Computing, Networking and Communications (ICNC), 2023, p.77-82

2023

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Catalytic Asymmetric Synthesis of Highly Functionalized Cyclopentenes by a [3 + 2] Cycloaddition

Journal of the American Chemical Society, 2001-08, Vol.123 (30), p.7461-7462

2001

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Zurletrectinib is a next-generation TRK inhibitor with strong intracranial activity against NTRK fusion-positive tumours with on-target resistance to first-generation agents

British journal of cancer, 2024-08, Vol.131 (3), p.601-610

2024

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Abstract 3655: Discovery of SC10914: a highly potent, selective and orally active PARP inhibitor for the treatment of BRCA1/2 deficient cancer

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.3655-3655

2015

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Abstract 2631: Discovery of SC110237, a highly potent, selective and orally active FLT3 inhibitor for the treatment of acute myeloid leukemia

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.2631-2631

2015

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Enantioselective Synthesis of Functionalized Tropanes by Rhodium(II) Carboxylate-Catalyzed Decomposition of Vinyldiazomethanes in the Presence of Pyrroles

Journal of organic chemistry, 1997-02, Vol.62 (4), p.1095-1105

1997

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Abstract 6187: ICP-723 is a potent pan-TRK Inhibitor with robust anti-tumor activities against wild-type and acquired drug-resistant mutations of NTRK fusions

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.6187-6187

2022

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Benzazepinones and Benzoxazepinones as Antagonists of Inhibitor of Apoptosis Proteins (IAPs) Selective for the Second Baculovirus IAP Repeat (BIR2) Domain

Journal of medicinal chemistry, 2013-10, Vol.56 (20), p.7772-7787

2013

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Synthesis of iodinated 3β-aryltropanes with selective binding to either the dopamine or serotonin transporters

Bioorganic & medicinal chemistry letters, 2002-03, Vol.12 (6), p.845-847

2002

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Characterization of a Novel Mitogen-Activated Protein Kinase Kinase 1/2 Inhibitor with a Unique Mechanism of Action for Cancer Therapy

Cancer research (Chicago, Ill.), 2009-03, Vol.69 (5), p.1924-1932

2009

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Asymmetric Synthesis of Cyclopentenes by [3 + 2] Annulations between Vinylcarbenoids and Vinyl Ethers

Journal of organic chemistry, 1998-09, Vol.63 (19), p.6586-6589

1998

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Synthesis and evaluation of a novel dirhodium tetraprolinate catalyst containing bridging prolinate ligands

Tetrahedron letters, 1997-06, Vol.38 (24), p.4203-4206

1997

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Synthesis of iodinated 3beta-aryltropanes with selective binding to either the dopamine or serotonin transporters

Bioorganic & medicinal chemistry letters, 2002-03, Vol.12 (6), p.845-847

2002

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Synthesis and monoamine transporter affinity of 3β-(4-(2-pyrrolyl)phenyl)-8-azabicyclo[3.2.1]octanes and 3β-(5-Indolyl)-8-azabicyclo[3.2.1]octanes

Bioorganic & medicinal chemistry letters, 2001-02, Vol.11 (4), p.487-489

2001

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Cell cycle inhibitors for the treatment of cancer

Drugs of the Future, 2003-09, Vol.28 (9), p.881

2003

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ChemInform Abstract: Synthesis of Iodinated 3β-Aryltropanes with Selective Binding to Either the Dopamine or Serotonin Transporters

ChemInform, 2002-07, Vol.33 (30), p.no-no

2002

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ChemInform Abstract: Catalytic Asymmetric Synthesis of Highly Functionalized Cyclopentenes by a [3 + 2] Cycloaddition

ChemInform, 2001-11, Vol.32 (48), p.no-no

2001

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ChemInform Abstract: Synthesis and Monoamine Transporter Affinity of 3β-(4-(2-Pyrrolyl)phenyl)-8-azabicyclo[3.2.1]octanes and 3β-(5-Indolyl)-8-azabicyclo[3.2.1]octanes

ChemInform, 2001-06, Vol.32 (24), p.no-no

2001

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Chronic mirabegron treatment increases human brown fat, HDL cholesterol, and insulin sensitivity

The Journal of clinical investigation, 2020-05, Vol.130 (5), p.2209-2219

2020

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Comparative transcriptomics of multidrug-resistant Acinetobacter baumannii in response to antibiotic treatments

Scientific reports, 2018-02, Vol.8 (1), p.3515-11, Article 3515

2018

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Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor

Science translational medicine, 2014-07, Vol.6 (243), p.243ra88

2014

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Glomerular Filtration Rate, Cardiorenal End Points, and All-Cause Mortality in Type 2 Diabetic Patients

Diabetes care, 2006-09, Vol.29 (9), p.2046-2052

2006

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In vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2

Asymmetric Cyclopropanations by Rhodium(II) N-(Arylsulfonyl)prolinate Catalyzed Decomposition of Vinyldiazomethanes in the Presence of Alkenes. Practical Enantioselective Synthesis of the Four Stereoisomers of 2-Phenylcyclopropan-1-amino Acid

Study on High Availability and Fault Tolerance

Catalytic Asymmetric Synthesis of Highly Functionalized Cyclopentenes by a [3 + 2] Cycloaddition

Zurletrectinib is a next-generation TRK inhibitor with strong intracranial activity against NTRK fusion-positive tumours with on-target resistance to first-generation agents

Abstract 3655: Discovery of SC10914: a highly potent, selective and orally active PARP inhibitor for the treatment of BRCA1/2 deficient cancer

Abstract 2631: Discovery of SC110237, a highly potent, selective and orally active FLT3 inhibitor for the treatment of acute myeloid leukemia

Enantioselective Synthesis of Functionalized Tropanes by Rhodium(II) Carboxylate-Catalyzed Decomposition of Vinyldiazomethanes in the Presence of Pyrroles

Abstract 6187: ICP-723 is a potent pan-TRK Inhibitor with robust anti-tumor activities against wild-type and acquired drug-resistant mutations of NTRK fusions

Benzazepinones and Benzoxazepinones as Antagonists of Inhibitor of Apoptosis Proteins (IAPs) Selective for the Second Baculovirus IAP Repeat (BIR2) Domain

Synthesis of iodinated 3β-aryltropanes with selective binding to either the dopamine or serotonin transporters

Characterization of a Novel Mitogen-Activated Protein Kinase Kinase 1/2 Inhibitor with a Unique Mechanism of Action for Cancer Therapy

Asymmetric Synthesis of Cyclopentenes by [3 + 2] Annulations between Vinylcarbenoids and Vinyl Ethers

Synthesis and evaluation of a novel dirhodium tetraprolinate catalyst containing bridging prolinate ligands

Synthesis of iodinated 3beta-aryltropanes with selective binding to either the dopamine or serotonin transporters

Synthesis and monoamine transporter affinity of 3β-(4-(2-pyrrolyl)phenyl)-8-azabicyclo[3.2.1]octanes and 3β-(5-Indolyl)-8-azabicyclo[3.2.1]octanes

Cell cycle inhibitors for the treatment of cancer

ChemInform Abstract: Synthesis of Iodinated 3β-Aryltropanes with Selective Binding to Either the Dopamine or Serotonin Transporters

ChemInform Abstract: Catalytic Asymmetric Synthesis of Highly Functionalized Cyclopentenes by a [3 + 2] Cycloaddition

ChemInform Abstract: Synthesis and Monoamine Transporter Affinity of 3β-(4-(2-Pyrrolyl)phenyl)-8-azabicyclo[3.2.1]octanes and 3β-(5-Indolyl)-8-azabicyclo[3.2.1]octanes

Chronic mirabegron treatment increases human brown fat, HDL cholesterol, and insulin sensitivity

Comparative transcriptomics of multidrug-resistant Acinetobacter baumannii in response to antibiotic treatments

Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor

Addressing challenges in low-income and middle-income countries through novel radiotherapy research opportunities

Glomerular Filtration Rate, Cardiorenal End Points, and All-Cause Mortality in Type 2 Diabetic Patients

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