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Role of the aryl hydrocarbon receptor in carcinogenesis and potential as an anti-cancer drug target

Archives of toxicology, 2017-07, Vol.91 (7), p.2497-2513

2017

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Molecular Analysis of ZNF71 KRAB in Non-Small-Cell Lung Cancer

International journal of molecular sciences, 2021-04, Vol.22 (7), p.3752

2021

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The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor

PloS one, 2010-10, Vol.5 (10), p.e13128

2010

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Benzimidazoisoquinolines: a new class of rapidly metabolized aryl hydrocarbon receptor (AhR) ligands that induce AhR-dependent Tregs and prevent murine graft-versus-host disease

PloS one, 2014-02, Vol.9 (2), p.e88726

2014

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The aryl hydrocarbon receptor mediates leflunomide-induced growth inhibition of melanoma cells

PloS one, 2012-07, Vol.7 (7), p.e40926-e40926

2012

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Modeling of the Aryl Hydrocarbon Receptor (AhR) Ligand Binding Domain and Its Utility in Virtual Ligand Screening to Predict New AhR Ligands

Journal of medicinal chemistry, 2009-09, Vol.52 (18), p.5635-5641

2009

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Retinoid X Receptor Regulates Nur77/Thyroid Hormone Receptor 3-Dependent Apoptosis by Modulating Its Nuclear Export and Mitochondrial Targeting

Molecular and Cellular Biology, 2004-11, Vol.24 (22), p.9705-9725

2004

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Cytochrome c Release and Apoptosis Induced by Mitochondrial Targeting of Nuclear Orphan Receptor TR3

Science (American Association for the Advancement of Science), 2000-08, Vol.289 (5482), p.1159-1164

2000

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Mitogenic Effect of Orphan Receptor TR3 and Its Regulation by MEKK1 in Lung Cancer Cells

Molecular and Cellular Biology, 2003-12, Vol.23 (23), p.8651-8667

2003

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Identification of a Raloxifene Analog That Promotes AhR-Mediated Apoptosis in Cancer Cells

Biology (Basel, Switzerland), 2017-12, Vol.6 (4), p.41

2017

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Nur77 converts phenotype of Bcl-B, an antiapoptotic protein expressed in plasma cells and myeloma

Blood, 2007-05, Vol.109 (9), p.3849-3855

2007

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The R-Enantiomer of the Nonsteroidal Antiinflammatory Drug Etodolac Binds Retinoid X Receptor and Induces Tumor-Selective Apoptosis

Proceedings of the National Academy of Sciences - PNAS, 2005-02, Vol.102 (7), p.2525-2530

2005

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Regulation of retinoic acid receptor β expression by peroxisome proliferator-activated receptor γ ligands in cancer cells

Cancer research (Chicago, Ill.), 2003-07, Vol.63 (13), p.3531-3538

2003

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Unique anti-activator protein-1 activity of retinoic acid receptor β

Cancer research (Chicago, Ill.), 2000-06, Vol.60 (12), p.3271-3280

2000

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Complementation of Ah Receptor Deficiency in Hepatoma Cells: Negative Feedback Regulation and Cell Cycle Control by the Ah Receptor

Experimental cell research, 1996-07, Vol.226 (1), p.154-163

1996

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Orphan Receptor COUP-TF Is Required for Induction of Retinoic Acid Receptor β, Growth Inhibition, and Apoptosis by Retinoic Acid in Cancer Cells

Molecular and Cellular Biology, 2000-02, Vol.20 (3), p.957-970

2000

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Novel target genes of the Ah (dioxin) receptor: Transcriptional induction of N-myristoyltransferase 2

Cancer research (Chicago, Ill.), 2001-12, Vol.61 (23), p.8534-8539

2001

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Apoptosis induction in cancer cells by a novel analogue of 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylic acid lacking retinoid receptor transcriptional activation activity

Cancer research (Chicago, Ill.), 2001-06, Vol.61 (12), p.4723-4730

2001

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Discovery and Mechanistic Characterization of a Select Modulator of AhR-regulated Transcription (SMAhRT) with Anti-cancer Effects

Apoptosis (London), 2021-06, Vol.26 (5-6), p.307-322

2021

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Erratum to: Role of the aryl hydrocarbon receptor in carcinogenesis and potential as an anti-cancer drug target

Archives of toxicology, 2017-09, Vol.91 (9), p.3209-3209

2017

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Conversion of Bcl-2 from Protector to Killer by Interaction with Nuclear Orphan Receptor Nur77/TR3

Cell, 2004-02, Vol.116 (4), p.527-540

2004

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Cancer therapeutics based on BCL-2 functional conversion

Apoptosis (London), 2019-02, Vol.24 (1-2), p.1-2

2019

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A Short Nur77-Derived Peptide Converts Bcl-2 from a Protector to a Killer

Cancer cell, 2008-10, Vol.14 (4), p.285-298

2008

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Regulation of Retinoic Acid-induced Inhibition of AP-1 Activity by Orphan Receptor Chicken Ovalbumin Upstream Promoter-Transcription Factor

The Journal of biological chemistry, 2002-06, Vol.277 (24), p.21414-21422

2002

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Induction of apoptosis and suppression of tumor growth by Nur77-derived Bcl-2 converting peptide in chemoresistant lung cancer cells

Oncotarget, 2018-05, Vol.9 (40), p.26072-26085

2018

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Role of the aryl hydrocarbon receptor in carcinogenesis and potential as an anti-cancer drug target

Molecular Analysis of ZNF71 KRAB in Non-Small-Cell Lung Cancer

The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor

Benzimidazoisoquinolines: a new class of rapidly metabolized aryl hydrocarbon receptor (AhR) ligands that induce AhR-dependent Tregs and prevent murine graft-versus-host disease

The aryl hydrocarbon receptor mediates leflunomide-induced growth inhibition of melanoma cells

Modeling of the Aryl Hydrocarbon Receptor (AhR) Ligand Binding Domain and Its Utility in Virtual Ligand Screening to Predict New AhR Ligands

Retinoid X Receptor Regulates Nur77/Thyroid Hormone Receptor 3-Dependent Apoptosis by Modulating Its Nuclear Export and Mitochondrial Targeting

Cytochrome c Release and Apoptosis Induced by Mitochondrial Targeting of Nuclear Orphan Receptor TR3

Mitogenic Effect of Orphan Receptor TR3 and Its Regulation by MEKK1 in Lung Cancer Cells

Identification of a Raloxifene Analog That Promotes AhR-Mediated Apoptosis in Cancer Cells

Nur77 converts phenotype of Bcl-B, an antiapoptotic protein expressed in plasma cells and myeloma

The R-Enantiomer of the Nonsteroidal Antiinflammatory Drug Etodolac Binds Retinoid X Receptor and Induces Tumor-Selective Apoptosis

Regulation of retinoic acid receptor β expression by peroxisome proliferator-activated receptor γ ligands in cancer cells

Unique anti-activator protein-1 activity of retinoic acid receptor β

Complementation of Ah Receptor Deficiency in Hepatoma Cells: Negative Feedback Regulation and Cell Cycle Control by the Ah Receptor

Orphan Receptor COUP-TF Is Required for Induction of Retinoic Acid Receptor β, Growth Inhibition, and Apoptosis by Retinoic Acid in Cancer Cells

Novel target genes of the Ah (dioxin) receptor: Transcriptional induction of N-myristoyltransferase 2

Apoptosis induction in cancer cells by a novel analogue of 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylic acid lacking retinoid receptor transcriptional activation activity

Discovery and Mechanistic Characterization of a Select Modulator of AhR-regulated Transcription (SMAhRT) with Anti-cancer Effects

Erratum to: Role of the aryl hydrocarbon receptor in carcinogenesis and potential as an anti-cancer drug target

Conversion of Bcl-2 from Protector to Killer by Interaction with Nuclear Orphan Receptor Nur77/TR3

Cancer therapeutics based on BCL-2 functional conversion

A Short Nur77-Derived Peptide Converts Bcl-2 from a Protector to a Killer

Regulation of Retinoic Acid-induced Inhibition of AP-1 Activity by Orphan Receptor Chicken Ovalbumin Upstream Promoter-Transcription Factor

Induction of apoptosis and suppression of tumor growth by Nur77-derived Bcl-2 converting peptide in chemoresistant lung cancer cells

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