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Drug discovery management, small is still beautiful: Why a number of companies get it wrong

Drug discovery today, 2011-06, Vol.16 (11), p.476-484

Knutsen, Lars J.S.

2011

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Discovery and Characterization of 6-{4-[3-(R)-2-Methylpyrrolidin-1-yl)propoxy]phenyl}-2H-pyridazin-3-one (CEP-26401, Irdabisant): A Potent, Selective Histamine H3 Receptor Inverse Agonist

Journal of medicinal chemistry, 2011-07, Vol.54 (13), p.4781-4792

2011

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Emerging Opportunities for Antipsychotic Drug Discovery in the Postgenomic Era

Journal of medicinal chemistry, 2008-03, Vol.51 (5), p.1077-1107

2008

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Explaining variation in Colorado songbird blood mercury using migratory behavior, foraging guild, and diet

Ecotoxicology (London), 2020-10, Vol.29 (8), p.1268-1280

2020

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Uncommon Upper Extremity Compression Neuropathies

Hand clinics, 2013-08, Vol.29 (3), p.443-453

2013

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Synthesis and SAR of novel 2-arylthiazolidinones as selective analgesic N-type calcium channel blockers

Bioorganic & medicinal chemistry letters, 2007-02, Vol.17 (3), p.662-667

2007

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Pleistocene stratigraphy and paleoenvironmental variation from Lomonosov Ridge sediments, central Arctic Ocean

Global and planetary change, 2001-11, Vol.31 (1), p.1-22

2001

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Infection of wild fishes by the parasitic copepod Caligus elongatus on the south east coast of Norway

Diseases of aquatic organisms, 2007-09, Vol.77 (2), p.149-158

2007

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Activity patterns of wild European lobster Homarus gammarus in coastal marine reserves: implications for future reserve design

Marine ecology. Progress series (Halstenbek), 2011-05, Vol.429, p.197-207

2011

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Hpz1 modulates the G1-S transition in fission yeast

PloS one, 2012-09, Vol.7 (9), p.e44539-e44539

2012

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Host preference of adult Caligus elongatus Nordmann in the laboratory and its implications for Atlantic cod aquaculture

Journal of fish diseases, 2006-03, Vol.29 (3), p.167-174

2006

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Factors Associated With Failure of Nonoperative Treatment in Lateral Epicondylitis

The American journal of sports medicine, 2015-09, Vol.43 (9), p.2133-2137

2015

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Lobster and cod benefit from small-scale northern marine protected areas: inference from an empirical before–after control-impact study

Proceedings of the Royal Society. B, Biological sciences, 2013-03, Vol.280 (1754), p.20122679-20122679

2013

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Life-history variation among local populations of Atlantic cod from the Norwegian Skagerrak coast

Journal of fish biology, 2004-06, Vol.64 (6), p.1725-1730

2004

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Marine feeding of anadromous Salmo trutta during winter

Journal of fish biology, 2004-01, Vol.64 (1), p.89-99

2004

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Is Satisfaction Among Orthopaedic Trauma Patients Predicted by Depression and Activation Levels?

Journal of orthopaedic trauma, 2015-05, Vol.29 (5), p.e183-e187

2015

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Particle concentration and yield stress of biomass slurries during enzymatic hydrolysis at high-solids loadings

Biotechnology and bioengineering, 2009-10, Vol.104 (2), p.290-300

2009

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Synthesis of Novel GABA Uptake Inhibitors. 3. Diaryloxime and Diarylvinyl Ether Derivatives of Nipecotic Acid and Guvacine as Anticonvulsant Agents

Journal of medicinal chemistry, 1999-09, Vol.42 (18), p.3447-3462

1999

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Cellulase retention and sugar removal by membrane ultrafiltration during lignocellulosic biomass hydrolysis

Applied biochemistry and biotechnology, 2004, Vol.113 (1-3), p.585-599

2004

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Biomarkers in fish from dioxin-contaminated fjords

Biomarkers, 2006-03, Vol.11 (2), p.97-117

2006

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Seasonal variation in marine growth of sea trout, Salmo trutta, in coastal Skagerrak

Ecology of freshwater fish, 2006-12, Vol.15 (4), p.446-452

2006

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Synthesis of Novel GABA Uptake Inhibitors. 4. Bioisosteric Transformation and Successive Optimization of Known GABA Uptake Inhibitors Leading to a Series of Potent Anticonvulsant Drug Candidates

Journal of medicinal chemistry, 1999-10, Vol.42 (21), p.4281-4291

1999

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Temporally distinct Escherichia coli O157 outbreaks associated with alfalfa sprouts linked to a common seed source – Colorado and Minnesota, 2003

Epidemiology and infection, 2005-06, Vol.133 (3), p.439-447

2005

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High-Strength Welds in Metallocene Polypropylene/Polyethylene Laminates

Science (American Association for the Advancement of Science), 2000-06, Vol.288 (5474), p.2187-2190

2000

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Drug discovery management, small is still beautiful: Why a number of companies get it wrong

Discovery and Characterization of 6-{4-[3-(R)-2-Methylpyrrolidin-1-yl)propoxy]phenyl}-2H-pyridazin-3-one (CEP-26401, Irdabisant): A Potent, Selective Histamine H3 Receptor Inverse Agonist

Emerging Opportunities for Antipsychotic Drug Discovery in the Postgenomic Era

Explaining variation in Colorado songbird blood mercury using migratory behavior, foraging guild, and diet

Uncommon Upper Extremity Compression Neuropathies

Synthesis and SAR of novel 2-arylthiazolidinones as selective analgesic N-type calcium channel blockers

Pleistocene stratigraphy and paleoenvironmental variation from Lomonosov Ridge sediments, central Arctic Ocean

Infection of wild fishes by the parasitic copepod Caligus elongatus on the south east coast of Norway

Activity patterns of wild European lobster Homarus gammarus in coastal marine reserves: implications for future reserve design

Hpz1 modulates the G1-S transition in fission yeast

The ClC-1 chloride channel inhibitor NMD670 improves skeletal muscle function in rat models and patients with myasthenia gravis

Host preference of adult Caligus elongatus Nordmann in the laboratory and its implications for Atlantic cod aquaculture

Factors Associated With Failure of Nonoperative Treatment in Lateral Epicondylitis

Lobster and cod benefit from small-scale northern marine protected areas: inference from an empirical before–after control-impact study

Life-history variation among local populations of Atlantic cod from the Norwegian Skagerrak coast

Marine feeding of anadromous Salmo trutta during winter

Is Satisfaction Among Orthopaedic Trauma Patients Predicted by Depression and Activation Levels?

Particle concentration and yield stress of biomass slurries during enzymatic hydrolysis at high-solids loadings

Synthesis of Novel GABA Uptake Inhibitors. 3. Diaryloxime and Diarylvinyl Ether Derivatives of Nipecotic Acid and Guvacine as Anticonvulsant Agents

Cellulase retention and sugar removal by membrane ultrafiltration during lignocellulosic biomass hydrolysis

Biomarkers in fish from dioxin-contaminated fjords

Seasonal variation in marine growth of sea trout, Salmo trutta, in coastal Skagerrak

Synthesis of Novel GABA Uptake Inhibitors. 4. Bioisosteric Transformation and Successive Optimization of Known GABA Uptake Inhibitors Leading to a Series of Potent Anticonvulsant Drug Candidates

Temporally distinct Escherichia coli O157 outbreaks associated with alfalfa sprouts linked to a common seed source – Colorado and Minnesota, 2003

High-Strength Welds in Metallocene Polypropylene/Polyethylene Laminates

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