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P.1.g.041 RG1662, a new negative allosteric modulator of the gamma-aminobutyric acid Aα5 receptor subtype, does not show convulsions at relevant doses

European neuropsychopharmacology, 2015-09, Vol.25, p.S259-S259

2015

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Characterization of RO4583298 as a novel potent, dual antagonist with in vivo activity at tachykinin NK1 and NK3 receptors

British journal of pharmacology, 2011-02, Vol.162 (4), p.929-946

2011

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Characterization of RO4583298 as a novel potent, dual antagonist with in vivo activity at tachykinin NK 1 and NK 3 receptors

British journal of pharmacology, 2011-02, Vol.162 (4), p.929-946

2011

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Potentiation of sensory responses in ventrobasal thalamus in vivo via selective modulation of mGlu1 receptors with a positive allosteric modulator

Neuropharmacology, 2012-03, Vol.62 (4), p.1695-1699

2012

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Modulation of Voltage-Gated Calcium Channels by Orphanin FQ in Freshly Dissociated Hippocampal Neurons

The Journal of neuroscience, 1996-11, Vol.16 (21), p.6657-6664

1996

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Positive Allosteric Modulators of Metabotropic Glutamate 1 Receptor: Characterization, Mechanism of Action, and Binding Site

Proceedings of the National Academy of Sciences - PNAS, 2001-11, Vol.98 (23), p.13402-13407

2001

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9H-Xanthene-9-carboxylic acid [1,2,4]oxadiazol-3-yl- and (2H-tetrazol-5-yl)-amides as potent, orally available mGlu1 receptor enhancers

Bioorganic & medicinal chemistry letters, 2005-10, Vol.15 (20), p.4628-4631

2005

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Mutational Analysis and Molecular Modeling of the Allosteric Binding Site of a Novel, Selective, Noncompetitive Antagonist of the Metabotropic Glutamate 1 Receptor

The Journal of biological chemistry, 2003-03, Vol.278 (10), p.8340-8347

2003

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Heterogeneity of GABAA-receptors : cell-specific expression, pharmacology, and regulation

Neurochemical research, 1995-05, Vol.20 (5), p.631-636

1995

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Benzodiazepine-Insensitive Mice Generated by Targeted Disruption of the γ2Subunit Gene of γ-Aminobutyric Acid Type A Receptors

Proceedings of the National Academy of Sciences - PNAS, 1995-08, Vol.92 (17), p.7749-7753

1995

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The γ3‐subunit of the GABAA‐receptor confers sensitivity to benzodiazepine receptor ligands

FEBS letters, 1991-11, Vol.293 (1-2), p.191-194

1991

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Identification of Essential Residues Involved in the Glutamate Binding Pocket of the Group II Metabotropic Glutamate Receptor

Molecular pharmacology, 2001-11, Vol.60 (5), p.944-954

2001

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Characterization of R04583298 as a novel potent, dual antagonist with in vivo activity at tachykinin NK1 and NK3 receptors

British journal of pharmacology, 2011, Vol.162 (4), p.929-946

2011

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Metabotropic glutamate group II receptors activate a G protein-coupled inwardly rectifying K+ current in neurones of the rat cerebellum

The Journal of physiology, 1998-06, Vol.509 (2), p.347-354

1998

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Characterization of behavioral response to amphetamine, tyrosine hydroxylase levels, and dopamine receptor levels in neurokinin 3 receptor knockout mice

Behavioural pharmacology, 2008-09, Vol.19 (5-6), p.518-529

2008

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Pharmacological and Electrophysiological Properties of Recombinant GABAA Receptors Comprising the α3, β1 and γ2 Subunits

The European journal of neuroscience, 1992-01, Vol.4 (1), p.1-9

1992

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Characterization of ( R , S )‐5,7‐di‐ tert ‐butyl‐3‐hydroxy‐3‐trifluoromethyl‐3 H ‐benzofuran‐2‐one as a positive allosteric modulator of GABA B receptors

British journal of pharmacology, 2009-01, Vol.154 (4), p.797-811

2009

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Pharmacological modulation of the diazepam-insensitive recombinant gamma-aminobutyric acidA receptors alpha 4 beta 2 gamma 2 and alpha 6 beta 2 gamma 2

Molecular pharmacology, 1996-11, Vol.50 (5), p.1253-1261

1996

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Characterization of (R,S)‐5,7‐di‐tert‐butyl‐3‐hydroxy‐3‐trifluoromethyl‐3H‐benzofuran‐2‐one as a positive allosteric modulator of GABAB receptors

British journal of pharmacology, 2008-06, Vol.154 (4), p.797-811

2008

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Benzodiazepine-insensitive mice generated by targeted disruption of the gamma 2 subunit gene of gamma-aminobutyric acid type A receptors

Proceedings of the National Academy of Sciences - PNAS, 1995-08, Vol.92 (17), p.7749-7753

1995

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Full and partial agonism displayed by benzodiazepine receptor ligands at recombinant gamma-aminobutyric acidA receptor subtypes

The Journal of pharmacology and experimental therapeutics, 1993-07, Vol.266 (1), p.385

1993

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Pharmacological properties of native metabotropic glutamate receptors in freshly dissociated Golgi cells of the rat cerebellum

Neuropharmacology, 2001, Vol.40 (2), p.163-169

2001

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Alkyl diphenylacetyl, 9H-xanthene- and 9H-thioxanthene-carbonyl carbamates as positive allosteric modulators of mGlu1 receptors

Farmaco (Società chimica italiana : 1989), 2002-12, Vol.57 (12), p.989-992

2002

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Multiple pathways for regulation of the KCl-induced [ 3H]-GABA release by metabotropic glutamate receptors, in primary rat cortical cultures

Brain research, 1998-01, Vol.782 (1), p.91-104

1998

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Pharmacological and Electrophysiological Properties of Recombinant GABAA Receptors Comprising the alpha3, beta1 and gamma2 Subunits

The European journal of neuroscience, 1992-10, Vol.4 (1), p.1-9

1992

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P.1.g.041 RG1662, a new negative allosteric modulator of the gamma-aminobutyric acid Aα5 receptor subtype, does not show convulsions at relevant doses

Characterization of RO4583298 as a novel potent, dual antagonist with in vivo activity at tachykinin NK1 and NK3 receptors

Characterization of RO4583298 as a novel potent, dual antagonist with in vivo activity at tachykinin NK 1 and NK 3 receptors

Potentiation of sensory responses in ventrobasal thalamus in vivo via selective modulation of mGlu1 receptors with a positive allosteric modulator

Modulation of Voltage-Gated Calcium Channels by Orphanin FQ in Freshly Dissociated Hippocampal Neurons

Positive Allosteric Modulators of Metabotropic Glutamate 1 Receptor: Characterization, Mechanism of Action, and Binding Site

9H-Xanthene-9-carboxylic acid [1,2,4]oxadiazol-3-yl- and (2H-tetrazol-5-yl)-amides as potent, orally available mGlu1 receptor enhancers

Mutational Analysis and Molecular Modeling of the Allosteric Binding Site of a Novel, Selective, Noncompetitive Antagonist of the Metabotropic Glutamate 1 Receptor

Heterogeneity of GABAA-receptors : cell-specific expression, pharmacology, and regulation

Benzodiazepine-Insensitive Mice Generated by Targeted Disruption of the γ2Subunit Gene of γ-Aminobutyric Acid Type A Receptors

The γ3‐subunit of the GABAA‐receptor confers sensitivity to benzodiazepine receptor ligands

Identification of Essential Residues Involved in the Glutamate Binding Pocket of the Group II Metabotropic Glutamate Receptor

Characterization of R04583298 as a novel potent, dual antagonist with in vivo activity at tachykinin NK1 and NK3 receptors

Metabotropic glutamate group II receptors activate a G protein-coupled inwardly rectifying K+ current in neurones of the rat cerebellum

Characterization of behavioral response to amphetamine, tyrosine hydroxylase levels, and dopamine receptor levels in neurokinin 3 receptor knockout mice

Pharmacological and Electrophysiological Properties of Recombinant GABAA Receptors Comprising the α3, β1 and γ2 Subunits

Characterization of ( R , S )‐5,7‐di‐ tert ‐butyl‐3‐hydroxy‐3‐trifluoromethyl‐3 H ‐benzofuran‐2‐one as a positive allosteric modulator of GABA B receptors

Pharmacological modulation of the diazepam-insensitive recombinant gamma-aminobutyric acidA receptors alpha 4 beta 2 gamma 2 and alpha 6 beta 2 gamma 2

Characterization of (R,S)‐5,7‐di‐tert‐butyl‐3‐hydroxy‐3‐trifluoromethyl‐3H‐benzofuran‐2‐one as a positive allosteric modulator of GABAB receptors

Benzodiazepine-insensitive mice generated by targeted disruption of the gamma 2 subunit gene of gamma-aminobutyric acid type A receptors

Full and partial agonism displayed by benzodiazepine receptor ligands at recombinant gamma-aminobutyric acidA receptor subtypes

Pharmacological properties of native metabotropic glutamate receptors in freshly dissociated Golgi cells of the rat cerebellum

Alkyl diphenylacetyl, 9H-xanthene- and 9H-thioxanthene-carbonyl carbamates as positive allosteric modulators of mGlu1 receptors

Multiple pathways for regulation of the KCl-induced [ 3H]-GABA release by metabotropic glutamate receptors, in primary rat cortical cultures

Pharmacological and Electrophysiological Properties of Recombinant GABAA Receptors Comprising the alpha3, beta1 and gamma2 Subunits

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