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Evolution of nonsteroidal anti-inflammatory drugs (NSAIDs): cyclooxygenase (COX) inhibition and beyond

Journal of pharmacy & pharmaceutical sciences, 2008-09, Vol.11 (2), p.81s

2008

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Design and Synthesis of Celecoxib and Rofecoxib Analogues as Selective Cyclooxygenase-2 (COX-2) Inhibitors: Replacement of Sulfonamide and Methylsulfonyl Pharmacophores by an Azido Bioisostere

Journal of medicinal chemistry, 2001-08, Vol.44 (18), p.3039-3042

2001

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Design and Synthesis of 4,5-Diphenyl-4-isoxazolines: Novel Inhibitors of Cyclooxygenase-2 with Analgesic and Antiinflammatory Activity

Journal of medicinal chemistry, 2001-08, Vol.44 (18), p.2921-2927

2001

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N-1 and C-3 substituted indole Schiff bases as selective COX-2 inhibitors: Synthesis and biological evaluation

Bioorganic & medicinal chemistry letters, 2012-03, Vol.22 (6), p.2154-2159

2012

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Ethanesulfohydroxamic Acid Ester Prodrugs of Nonsteroidal Anti-inflammatory Drugs (NSAIDs): Synthesis, Nitric oxide and Nitroxyl Release, Cyclooxygenase Inhibition, Anti-inflammatory, and Ulcerogenicity Index Studies

Journal of medicinal chemistry, 2011-03, Vol.54 (5), p.1356-1364

2011

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Synthesis and Structure−Activity Relationship Studies of 1,3-Diarylprop-2-yn-1-ones: Dual Inhibitors of Cyclooxygenases and Lipoxygenases

Journal of medicinal chemistry, 2006-03, Vol.49 (5), p.1668-1683

2006

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Novel approaches for designing 5'-O-ester prodrugs of 3'-azido-2', 3'-dideoxythymidine (AZT)

Current medicinal chemistry, 2000-10, Vol.7 (10), p.995

2000

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Design, Synthesis, and Biological Evaluation of 6-Substituted-3-(4-methanesulfonylphenyl)-4-phenylpyran-2-ones: A Novel Class of Diarylheterocyclic Selective Cyclooxygenase-2 Inhibitors

Journal of medicinal chemistry, 2003-11, Vol.46 (23), p.4872-4882

2003

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Suppression of network activity in dorsal horn by gabapentin permeation of TRPV1 channels: Implications for drug access to cytoplasmic targets

Neuroscience letters, 2015-01, Vol.584, p.397-402

2015

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Pulmonary Artery and Intercostal Artery Pseudoaneurysms After Penetrating Injury

The Annals of thoracic surgery, 2021-11, Vol.112 (5), p.e353-e355

2021

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Social Determinants of Health and Hirschsprung-associated Enterocolitis

Journal of pediatric surgery, 2023-08, Vol.58 (8), p.1458-1462

2023

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Novel Nonsteroidal Antiinflammatory Drugs Possessing a Nitric Oxide Donor Diazen-1-ium-1,2-diolate Moiety: Design, Synthesis, Biological Evaluation, and Nitric Oxide Release Studies

Journal of medicinal chemistry, 2005-06, Vol.48 (12), p.4061-4067

2005

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Sociodemographic Differences in Care Plans and Time to Treatment Among Children Being Considered for Adenotonsillectomy

Otolaryngology-head and neck surgery, 2022-06, Vol.166 (6), p.1106-1117

2022

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Design, Synthesis, and Structure−Activity Relationship Studies of 3,4,6-Triphenylpyran-2-ones as Selective Cyclooxygenase-2 Inhibitors

Journal of medicinal chemistry, 2004-07, Vol.47 (16), p.3972-3990

2004

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Design, synthesis, and biological evaluation of 1,3-diarylprop-2-en-1-ones : A novel class of cyclooxygenase-2 inhibitors

Bioorganic & medicinal chemistry, 2006-04, Vol.14 (8), p.2600-2605

2006

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Electrophysiological characterization of a recombinant human Na+-coupled nucleoside transporter (hCNT1) produced in Xenopus oocytes

The Journal of physiology, 2004-08, Vol.558 (3), p.807-823

2004

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Reply to Letter to the Editor by Priyadarsini A, et al

Journal of pediatric surgery, 2022-11, Vol.57 (11), p.750-750

2022

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Design and Synthesis of 3‘- and 5‘-O-(3-Benzenesulfonylfuroxan-4-yl)-2‘-deoxyuridines: Biological Evaluation as Hybrid Nitric Oxide Donor−Nucleoside Anticancer Agents

Journal of medicinal chemistry, 2004-03, Vol.47 (7), p.1840-1846

2004

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Glutathione S‑Transferase π‑Activatable O 2‑(Sulfonylethyl Derived) Diazeniumdiolates Potently Suppress Melanoma in Vitro and in Vivo

Journal of medicinal chemistry, 2018-03, Vol.61 (5), p.1833-1844

2018

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Routine botulinum toxin injection one month after a Swenson pull-through does not change the incidence of Hirschsprung associated enterocolitis

Journal of pediatric surgery, 2022-08, Vol.57 (8), p.1453-1457

2022

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Antegrade continence enemas in children with functional constipation and dyssynergic defecation: Go or no go?

Journal of pediatric surgery, 2022-08, Vol.57 (8), p.1672-1675

2022

Volltextzugriff (PDF)

Dinitroglyceryl and diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of aspirin, indomethacin and ibuprofen: Synthesis, biological evaluation and nitric oxide release studies

Bioorganic & medicinal chemistry letters, 2009-06, Vol.19 (11), p.3014-3018

2009

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Impact of Neurodevelopmental Disorders on Bowel Management Outcomes in Children with Functional Constipation

Journal of pediatric gastroenterology and nutrition, 2022-09, Vol.75 (3), p.286-292

2022

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Improvement in bladder function in children with functional constipation after a bowel management program

Pediatric surgery international, 2022-10, Vol.38 (10), p.1473-1479

2022

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Both sides of the screen: Provider and patient perspective on telemedicine in pediatric surgery

Journal of pediatric surgery, 2022-08, Vol.57 (8), p.1614-1621

2022

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Evolution of nonsteroidal anti-inflammatory drugs (NSAIDs): cyclooxygenase (COX) inhibition and beyond

Design and Synthesis of Celecoxib and Rofecoxib Analogues as Selective Cyclooxygenase-2 (COX-2) Inhibitors: Replacement of Sulfonamide and Methylsulfonyl Pharmacophores by an Azido Bioisostere

Design and Synthesis of 4,5-Diphenyl-4-isoxazolines: Novel Inhibitors of Cyclooxygenase-2 with Analgesic and Antiinflammatory Activity

N-1 and C-3 substituted indole Schiff bases as selective COX-2 inhibitors: Synthesis and biological evaluation

Ethanesulfohydroxamic Acid Ester Prodrugs of Nonsteroidal Anti-inflammatory Drugs (NSAIDs): Synthesis, Nitric oxide and Nitroxyl Release, Cyclooxygenase Inhibition, Anti-inflammatory, and Ulcerogenicity Index Studies

Synthesis and Structure−Activity Relationship Studies of 1,3-Diarylprop-2-yn-1-ones: Dual Inhibitors of Cyclooxygenases and Lipoxygenases

Novel approaches for designing 5'-O-ester prodrugs of 3'-azido-2', 3'-dideoxythymidine (AZT)

Design, Synthesis, and Biological Evaluation of 6-Substituted-3-(4-methanesulfonylphenyl)-4-phenylpyran-2-ones: A Novel Class of Diarylheterocyclic Selective Cyclooxygenase-2 Inhibitors

Suppression of network activity in dorsal horn by gabapentin permeation of TRPV1 channels: Implications for drug access to cytoplasmic targets

Pulmonary Artery and Intercostal Artery Pseudoaneurysms After Penetrating Injury

Social Determinants of Health and Hirschsprung-associated Enterocolitis

Novel Nonsteroidal Antiinflammatory Drugs Possessing a Nitric Oxide Donor Diazen-1-ium-1,2-diolate Moiety: Design, Synthesis, Biological Evaluation, and Nitric Oxide Release Studies

Sociodemographic Differences in Care Plans and Time to Treatment Among Children Being Considered for Adenotonsillectomy

Design, Synthesis, and Structure−Activity Relationship Studies of 3,4,6-Triphenylpyran-2-ones as Selective Cyclooxygenase-2 Inhibitors

Design, synthesis, and biological evaluation of 1,3-diarylprop-2-en-1-ones : A novel class of cyclooxygenase-2 inhibitors

Electrophysiological characterization of a recombinant human Na+-coupled nucleoside transporter (hCNT1) produced in Xenopus oocytes

Reply to Letter to the Editor by Priyadarsini A, et al

Design and Synthesis of 3‘- and 5‘-O-(3-Benzenesulfonylfuroxan-4-yl)-2‘-deoxyuridines: Biological Evaluation as Hybrid Nitric Oxide Donor−Nucleoside Anticancer Agents

Glutathione S‑Transferase π‑Activatable O 2‑(Sulfonylethyl Derived) Diazeniumdiolates Potently Suppress Melanoma in Vitro and in Vivo

Routine botulinum toxin injection one month after a Swenson pull-through does not change the incidence of Hirschsprung associated enterocolitis

Antegrade continence enemas in children with functional constipation and dyssynergic defecation: Go or no go?

Dinitroglyceryl and diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of aspirin, indomethacin and ibuprofen: Synthesis, biological evaluation and nitric oxide release studies

Impact of Neurodevelopmental Disorders on Bowel Management Outcomes in Children with Functional Constipation

Improvement in bladder function in children with functional constipation after a bowel management program

Both sides of the screen: Provider and patient perspective on telemedicine in pediatric surgery

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