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Matrigel: From discovery and ECM mimicry to assays and models for cancer research

Advanced drug delivery reviews, 2014-12, Vol.79-80, p.3-18

2014

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In vitro microtumors provide a physiologically predictive tool for breast cancer therapeutic screening

PloS one, 2015-04, Vol.10 (4), p.e0123312-e0123312

2015

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The endothelial cell tube formation assay on basement membrane turns 20: state of the science and the art

Angiogenesis (London), 2009-09, Vol.12 (3), p.267-274

2009

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Hematogenous metastasis and tumor dormancy as concepts or dogma? The continuum of vessel co-option and angiotropic extravascular migratory metastasis as an alternative

Frontiers in oncology, 2022-10, Vol.12, p.996411

2022

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Angiotropism, pericytic mimicry and extravascular migratory metastasis: an embryogenesis-derived program of tumor spread

Angiogenesis (London), 2020-02, Vol.23 (1), p.27-41

2020

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Imaging of Angiotropism/Vascular Co-Option in a Murine Model of Brain Melanoma: Implications for Melanoma Progression along Extravascular Pathways

Scientific reports, 2016-04, Vol.6 (1), p.23834-23834, Article 23834

2016

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0.1% RGN-259 (Thymosin ß4) Ophthalmic Solution Promotes Healing and Improves Comfort in Neurotrophic Keratopathy Patients in a Randomized, Placebo-Controlled, Double-Masked Phase III Clinical Trial

International journal of molecular sciences, 2022-12, Vol.24 (1), p.554

2022

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RGN-259 (thymosin β4) improves clinically important dry eye efficacies in comparison with prescription drugs in a dry eye model

Scientific reports, 2018-07, Vol.8 (1), p.10500-14, Article 10500

2018

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In vitro angiogenesis: endothelial cell tube formation on gelled basement membrane extract

Nature protocols, 2010-04, Vol.5 (4), p.628-635

2010

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Thymosin β4: a multi-functional regenerative peptide. Basic properties and clinical applications

Expert opinion on biological therapy, 2012-01, Vol.12 (1), p.37-51

2012

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Increased initiation and growth of tumor cell lines, cancer stem cells and biopsy material in mice using basement membrane matrix protein (Cultrex or Matrigel) co-injection

Nature protocols, 2012-06, Vol.7 (6), p.1138-1144

2012

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Role of the extracellular matrix in morphogenesis

Current opinion in biotechnology, 2003-10, Vol.14 (5), p.526-532

2003

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Thymosin β4: potential to treat epidermolysis bullosa and other severe dermal injuries

EJD. European journal of dermatology, 2019-10, Vol.29 (5), p.459-467

2019

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Safety and potential efficacy of gemfibrozil as a supportive treatment for children with late infantile neuronal ceroid lipofuscinosis and other lipid storage disorders

Orphanet journal of rare diseases, 2017-06, Vol.12 (1), p.113-113, Article 113

2017

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Cell-cell and cell-extracellular matrix interactions regulate embryonic stem cell differentiation

Stem cells (Dayton, Ohio), 2007-03, Vol.25 (3), p.553-561

2007

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The basement membrane matrix in malignancy

The Journal of pathology, 2003-07, Vol.200 (4), p.465-470

2003

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Matrigel: history/background, uses, and future applications

Journal of cell communication and signaling, 2022-12, Vol.16 (4), p.621-626

2022

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Thymosin β4 significantly reduces the signs of dryness in a murine controlled adverse environment model of experimental dry eye

Expert opinion on biological therapy, 2015-06, Vol.15 (sup1), p.155-161

2015

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Neuropeptide Y induces migration, proliferation, and tube formation of endothelial cells bimodally via Y1, Y2, and Y5 receptors

The FASEB journal, 2006-09, Vol.20 (11), p.1924-1926

2006

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Multiple uses of basement membrane‐like matrix (BME/Matrigel) in vitro and in vivo with cancer cells

International journal of cancer, 2011-04, Vol.128 (8), p.1751-1757

2011

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Primary Mechanisms of Thymosin β4 Repair Activity in Dry Eye Disorders and Other Tissue Injuries

Investigative ophthalmology & visual science, 2015-08, Vol.56 (9), p.5110-5117

2015

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Matrigel: Basement membrane matrix with biological activity

Seminars in cancer biology, 2005-10, Vol.15 (5), p.378-386

2005

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Gene expression profiles of mouse submandibular gland development: FGFR1 regulates branching morphogenesis in vitro through BMP- and FGF-dependent mechanisms

Development (Cambridge), 2002-12, Vol.129 (24), p.5767-5778

2002

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Thymosin β4 and the anti-fibrotic switch

International immunopharmacology, 2023-02, Vol.115, p.109628, Article 109628

2023

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Eotaxin (CCL11) Induces In Vivo Angiogenic Responses by Human CCR3+ Endothelial Cells

The Journal of immunology (1950), 2001-06, Vol.166 (12), p.7571-7578

2001

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Matrigel: From discovery and ECM mimicry to assays and models for cancer research

In vitro microtumors provide a physiologically predictive tool for breast cancer therapeutic screening

The endothelial cell tube formation assay on basement membrane turns 20: state of the science and the art

Hematogenous metastasis and tumor dormancy as concepts or dogma? The continuum of vessel co-option and angiotropic extravascular migratory metastasis as an alternative

Angiotropism, pericytic mimicry and extravascular migratory metastasis: an embryogenesis-derived program of tumor spread

Imaging of Angiotropism/Vascular Co-Option in a Murine Model of Brain Melanoma: Implications for Melanoma Progression along Extravascular Pathways

0.1% RGN-259 (Thymosin ß4) Ophthalmic Solution Promotes Healing and Improves Comfort in Neurotrophic Keratopathy Patients in a Randomized, Placebo-Controlled, Double-Masked Phase III Clinical Trial

RGN-259 (thymosin β4) improves clinically important dry eye efficacies in comparison with prescription drugs in a dry eye model

In vitro angiogenesis: endothelial cell tube formation on gelled basement membrane extract

Thymosin β4: a multi-functional regenerative peptide. Basic properties and clinical applications

Increased initiation and growth of tumor cell lines, cancer stem cells and biopsy material in mice using basement membrane matrix protein (Cultrex or Matrigel) co-injection

Role of the extracellular matrix in morphogenesis

Thymosin β4: potential to treat epidermolysis bullosa and other severe dermal injuries

Safety and potential efficacy of gemfibrozil as a supportive treatment for children with late infantile neuronal ceroid lipofuscinosis and other lipid storage disorders

Cell-cell and cell-extracellular matrix interactions regulate embryonic stem cell differentiation

The basement membrane matrix in malignancy

Matrigel: history/background, uses, and future applications

Thymosin β4 significantly reduces the signs of dryness in a murine controlled adverse environment model of experimental dry eye

Neuropeptide Y induces migration, proliferation, and tube formation of endothelial cells bimodally via Y1, Y2, and Y5 receptors

Multiple uses of basement membrane‐like matrix (BME/Matrigel) in vitro and in vivo with cancer cells

Primary Mechanisms of Thymosin β4 Repair Activity in Dry Eye Disorders and Other Tissue Injuries

Matrigel: Basement membrane matrix with biological activity

Gene expression profiles of mouse submandibular gland development: FGFR1 regulates branching morphogenesis in vitro through BMP- and FGF-dependent mechanisms

Thymosin β4 and the anti-fibrotic switch

Eotaxin (CCL11) Induces In Vivo Angiogenic Responses by Human CCR3+ Endothelial Cells

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