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Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice

Proceedings of the National Academy of Sciences - PNAS, 2008-08, Vol.105 (32), p.11105-11109

2008

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Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo

Proceedings of the National Academy of Sciences - PNAS, 2007-05, Vol.104 (21), p.8749-8754

2007

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Fluorination in Medicinal Chemistry: Methods, Strategies, and Recent Developments

Organic process research & development, 2008-03, Vol.12 (2), p.305-321

Kirk, Kenneth L

2008

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Identification of arsenic-binding proteins in human breast cancer cells

Cancer letters, 2007-09, Vol.255 (1), p.95-106

2007

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Robert Filler 1923–2019

Journal of fluorine chemistry, 2019-12, Vol.228, p.109341, Article 109341

Kirk, Kenneth L.

2019

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Selective fluorination in drug design and development: an overview of biochemical rationales

Current topics in medicinal chemistry, 2006-07, Vol.6 (14), p.1447-1456

Kirk, Kenneth L

2006

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Enantioselective Fluorination Mediated by N-Fluoroammonium Salts of Cinchona Alkaloids: First Enantioselective Synthesis of BMS-204352 (MaxiPost)

Journal of organic chemistry, 2003-03, Vol.68 (6), p.2494-2497

2003

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Gc Protein (Vitamin D-binding Protein): Gc Genotyping and GcMAF Precursor Activity

Anticancer research, 2005-11, Vol.25 (6A), p.3689-3695

2005

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Fluorinated phenylcyclopropylamines. Part 5: Effects of electron-withdrawing or -donating aryl substituents on the inhibition of monoamine oxidases A and B by 2-aryl-2-fluoro-cyclopropylamines

Bioorganic & medicinal chemistry, 2008-08, Vol.16 (15), p.7148-7166

2008

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Design of antiangiogenic hypoxic cell radiosensitizers: 2-Nitroimidazoles containing a 2-aminomethylene-4-cyclopentene-1,3-dione moiety

Bioorganic & medicinal chemistry, 2008-06, Vol.16 (11), p.6042-6053

2008

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John W. Daly - An Appreciation

Heterocycles, 2009, Vol.79 (1), p.61-71

2009

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Fluorinated Phenylcyclopropylamines. 2. Effects of Aromatic Ring Substitution and of Absolute Configuration on Inhibition of Microbial Tyramine Oxidase

Journal of medicinal chemistry, 2004-11, Vol.47 (24), p.5860-5871

2004

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John W. Daly: The Early Years. The NIH Shift and Cyclic-AMP Assays: Early Pharmacological Breakthroughs

Heterocycles, 2009-04, Vol.79 (1), p.85

2009

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Fluorine in medicinal chemistry: Recent therapeutic applications of fluorinated small molecules

Journal of fluorine chemistry, 2006-08, Vol.127 (8), p.1013-1029

Kirk, Kenneth L.

2006

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Fluorinated Phenylcyclopropylamines. 1. Synthesis and Effect of Fluorine Substitution at the Cyclopropane Ring on Inhibition of Microbial Tyramine Oxidase

Journal of medicinal chemistry, 2004-03, Vol.47 (7), p.1796-1806

2004

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Synthesis and biological activities of fluorinated chalcone derivatives

Bioorganic & medicinal chemistry, 2002-03, Vol.10 (3), p.699-706

2002

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Angiogenesis inhibitor TX-1898: syntheses of the enantiomers of sterically diverse haloacetylcarbamoyl-2-nitroimidazole hypoxic cell radiosensitizers

Bioorganic & medicinal chemistry, 2004-09, Vol.12 (18), p.4917-4927

2004

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Oxidative Inactivation of the Lipid Phosphatase Phosphatase and Tensin Homolog on Chromosome Ten (PTEN) as a Novel Mechanism of Acquired Long QT Syndrome

The Journal of biological chemistry, 2011-01, Vol.286 (4), p.2843-2852

2011

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An improved synthesis of arsenic–biotin conjugates

Bioorganic & medicinal chemistry, 2008-05, Vol.16 (10), p.5743-5746

2008

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Photochemical Schiemann reaction in ionic liquids

Journal of fluorine chemistry, 2007-06, Vol.128 (6), p.674-678

2007

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A convenient synthesis of the C-1-phosphonate analogue of UDP-GlcNAc and its evaluation as an inhibitor of O-linked GlcNAc transferase (OGT)

Carbohydrate research, 2008-02, Vol.343 (2), p.189-195

2008

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6-Bromo-6-deoxy-L-ascorbic acid: an ascorbate analog specific for Na+-dependent vitamin C transporter but not glucose transporter pathways

The Journal of biological chemistry, 2005-02, Vol.280 (7), p.5211-5220

2005

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Synthesis of 2‘,5‘-Dideoxy-2-fluoroadenosine and 2‘,5‘-Dideoxy-2,5‘-difluoroadenosine: Potent P-Site Inhibitors of Adenylyl Cyclase

Journal of medicinal chemistry, 2004-02, Vol.47 (5), p.1207-1213

2004

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Molecular recognition in the P2Y14 receptor: Probing the structurally permissive terminal sugar moiety of uridine-5'-diphosphoglucose

Bioorganic & medicinal chemistry, 2009-07, Vol.17 (14), p.5298-5311

2009

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Structural basis of the selectivity of the β2-adrenergic receptor for fluorinated catecholamines

Bioorganic & medicinal chemistry, 2009-12, Vol.17 (23), p.7987-7992

2009

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Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice

Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo

Fluorination in Medicinal Chemistry: Methods, Strategies, and Recent Developments

Identification of arsenic-binding proteins in human breast cancer cells

Robert Filler 1923–2019

Selective fluorination in drug design and development: an overview of biochemical rationales

Enantioselective Fluorination Mediated by N-Fluoroammonium Salts of Cinchona Alkaloids: First Enantioselective Synthesis of BMS-204352 (MaxiPost)

Gc Protein (Vitamin D-binding Protein): Gc Genotyping and GcMAF Precursor Activity

Fluorinated phenylcyclopropylamines. Part 5: Effects of electron-withdrawing or -donating aryl substituents on the inhibition of monoamine oxidases A and B by 2-aryl-2-fluoro-cyclopropylamines

Design of antiangiogenic hypoxic cell radiosensitizers: 2-Nitroimidazoles containing a 2-aminomethylene-4-cyclopentene-1,3-dione moiety

John W. Daly - An Appreciation

Fluorinated Phenylcyclopropylamines. 2. Effects of Aromatic Ring Substitution and of Absolute Configuration on Inhibition of Microbial Tyramine Oxidase

John W. Daly: The Early Years. The NIH Shift and Cyclic-AMP Assays: Early Pharmacological Breakthroughs

Fluorine in medicinal chemistry: Recent therapeutic applications of fluorinated small molecules

Fluorinated Phenylcyclopropylamines. 1. Synthesis and Effect of Fluorine Substitution at the Cyclopropane Ring on Inhibition of Microbial Tyramine Oxidase

Synthesis and biological activities of fluorinated chalcone derivatives

Angiogenesis inhibitor TX-1898: syntheses of the enantiomers of sterically diverse haloacetylcarbamoyl-2-nitroimidazole hypoxic cell radiosensitizers

Oxidative Inactivation of the Lipid Phosphatase Phosphatase and Tensin Homolog on Chromosome Ten (PTEN) as a Novel Mechanism of Acquired Long QT Syndrome

An improved synthesis of arsenic–biotin conjugates

Photochemical Schiemann reaction in ionic liquids

A convenient synthesis of the C-1-phosphonate analogue of UDP-GlcNAc and its evaluation as an inhibitor of O-linked GlcNAc transferase (OGT)

6-Bromo-6-deoxy-L-ascorbic acid: an ascorbate analog specific for Na+-dependent vitamin C transporter but not glucose transporter pathways

Synthesis of 2‘,5‘-Dideoxy-2-fluoroadenosine and 2‘,5‘-Dideoxy-2,5‘-difluoroadenosine: Potent P-Site Inhibitors of Adenylyl Cyclase

Molecular recognition in the P2Y14 receptor: Probing the structurally permissive terminal sugar moiety of uridine-5'-diphosphoglucose

Structural basis of the selectivity of the β2-adrenergic receptor for fluorinated catecholamines

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