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CYP2D6 Phenotype Prediction From Genotype: Which System Is the Best?

Clinical pharmacology and therapeutics, 2008-02, Vol.83 (2), p.225-227

Kirchheiner, J

2008

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Pharmacokinetics of codeine and its metabolite morphine in ultra-rapid metabolizers due to CYP2D6 duplication

The pharmacogenomics journal, 2007-08, Vol.7 (4), p.257-265

2007

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Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response

Molecular psychiatry, 2004-05, Vol.9 (5), p.442-473

2004

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Appropriate Phenotyping Procedures for Drug Metabolizing Enzymes and Transporters in Humans and Their Simultaneous Use in the "Cocktail" Approach

Clinical pharmacology and therapeutics, 2007-02, Vol.81 (2), p.270-283

2007

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Effect of an Antiretroviral Regimen Containing Ritonavir Boosted Lopinavir on Intestinal and Hepatic CYP3A, CYP2D6 and P-glycoprotein in HIV-infected Patients

Clinical pharmacology and therapeutics, 2008-07, Vol.84 (1), p.75-82

2008

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The clinical role of genetic polymorphisms in drug-metabolizing enzymes

The pharmacogenomics journal, 2008-02, Vol.8 (1), p.4-15

2008

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CYP2D6 and CYP2C19 genotype-based dose recommendations for antidepressants:a first step towards subpopulation-specific dosages

Acta psychiatrica Scandinavica, 2001-09, Vol.104 (3), p.173-192

2001

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Pharmacogenetics in psychiatry--a useful clinical tool or wishful thinking for the future?

Current pharmaceutical design, 2010, Vol.16 (2), p.136-144

2010

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Assessment of Activity Levels for CYP2D61, CYP2D62, and CYP2D641 Genes by Population Pharmacokinetics of Dextromethorphan

Clinical pharmacology and therapeutics, 2010-11, Vol.88 (5), p.643-651

2010

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Relative Impact of Genotype and Enzyme Induction on the Metabolic Capacity of CYP2C9 in Healthy Volunteers

Clinical pharmacology and therapeutics, 2009-07, Vol.86 (1), p.54-61

2009

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Influence of CYP2C9 polymorphisms on the pharmacokinetics and cholesterol‐lowering activity of (−)‐3s,5r‐fluvastatin and (+)‐3r,5s‐fluvastatin in healthy volunteers

Clinical pharmacology and therapeutics, 2003-08, Vol.74 (2), p.186-194

2003

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Association between CYP2C9 slow metabolizer genotypes and severe hypoglycaemia on medication with sulphonylurea hypoglycaemic agents

British journal of clinical pharmacology, 2005-07, Vol.60 (1), p.103-106

2005

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Why, When, and How Should Pharmacogenetics Be Applied in Clinical Studies?: Current and Future Approaches to Study Designs

Clinical pharmacology and therapeutics, 2011-02, Vol.89 (2), p.198-209

2011

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Pharmacokinetics and pharmacodynamics of rosiglitazone in relation to CYP2C8 genotype

Clinical pharmacology and therapeutics, 2006-12, Vol.80 (6), p.657-667

2006

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CYP2D6 in the brain: genotype effects on resting brain perfusion

Molecular psychiatry, 2011-03, Vol.16 (3), p.333-341

2011

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Pharmacokinetics of Mirtazapine: Enantioselective Effects of the CYP2D6 Ultra Rapid Metabolizer Genotype and Correlation with Adverse Effects

Clinical pharmacology and therapeutics, 2007-05, Vol.81 (5), p.699-707

2007

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Serotonin Syndrome With Tramadol and Citalopram

The American journal of psychiatry, 2004-06, Vol.161 (6), p.1129-1129

2004

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A 40-basepair VNTR polymorphism in the dopamine transporter (DAT1) gene and the rapid response to antidepressant treatment

The pharmacogenomics journal, 2007-02, Vol.7 (1), p.48-55

2007

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Pharmacogenomics Education: International Society of Pharmacogenomics Recommendations for Medical, Pharmaceutical, and Health Schools Deans of Education

The pharmacogenomics journal, 2005-08, Vol.5 (4), p.221-225

2005

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Effect of propiverine on cytochrome P450 enzymes: a cocktail interaction study in healthy volunteers

Drug metabolism and disposition, 2005-12, Vol.33 (12), p.1859

2005

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Genetic variants of the insulin receptor substrate-1 are influencing the therapeutic efficacy of oral antidiabetics

Diabetes, obesity & metabolism, 2010-12, Vol.12 (12), p.1106-1112

2010

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CYP2D6 Ultrarapid Metabolism and Morphine/Codeine Ratios in Blood: Was it Codeine or Heroin?

Journal of analytical toxicology, 2008-03, Vol.32 (2), p.178-182

2008

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A novel presenilin1 mutation (Q223R) associated with early onset Alzheimer's disease, dysarthria and spastic paraparesis and decreased Abeta levels in CSF

European journal of neurology, 2010-04, Vol.17 (4), p.631-633

2010

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Individualized Medicine - Implementation of Pharmacogenetic Diagnostics in Antidepressant Drug Treatment of Major Depressive Disorders

PHARMACOPSYCHIATRY, 2003, Vol.36 (S 3), p.235-243

2003

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Assessment of Activity Levels for CYP2D61, CYP2D62, and CYP2D641 Genes by Population Pharmacokinetics of Dextromethorphan

Clinical pharmacology and therapeutics, 2010-09, Vol.88 (5), p.643-651

2010

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CYP2D6 Phenotype Prediction From Genotype: Which System Is the Best?

Pharmacokinetics of codeine and its metabolite morphine in ultra-rapid metabolizers due to CYP2D6 duplication

Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response

Appropriate Phenotyping Procedures for Drug Metabolizing Enzymes and Transporters in Humans and Their Simultaneous Use in the "Cocktail" Approach

Effect of an Antiretroviral Regimen Containing Ritonavir Boosted Lopinavir on Intestinal and Hepatic CYP3A, CYP2D6 and P-glycoprotein in HIV-infected Patients

The clinical role of genetic polymorphisms in drug-metabolizing enzymes

CYP2D6 and CYP2C19 genotype-based dose recommendations for antidepressants:a first step towards subpopulation-specific dosages

Pharmacogenetics in psychiatry--a useful clinical tool or wishful thinking for the future?

Assessment of Activity Levels for CYP2D61, CYP2D62, and CYP2D641 Genes by Population Pharmacokinetics of Dextromethorphan

Relative Impact of Genotype and Enzyme Induction on the Metabolic Capacity of CYP2C9 in Healthy Volunteers

Influence of CYP2C9 polymorphisms on the pharmacokinetics and cholesterol‐lowering activity of (−)‐3s,5r‐fluvastatin and (+)‐3r,5s‐fluvastatin in healthy volunteers

Association between CYP2C9 slow metabolizer genotypes and severe hypoglycaemia on medication with sulphonylurea hypoglycaemic agents

Why, When, and How Should Pharmacogenetics Be Applied in Clinical Studies?: Current and Future Approaches to Study Designs

Pharmacokinetics and pharmacodynamics of rosiglitazone in relation to CYP2C8 genotype

CYP2D6 in the brain: genotype effects on resting brain perfusion

Pharmacokinetics of Mirtazapine: Enantioselective Effects of the CYP2D6 Ultra Rapid Metabolizer Genotype and Correlation with Adverse Effects

Serotonin Syndrome With Tramadol and Citalopram

A 40-basepair VNTR polymorphism in the dopamine transporter (DAT1) gene and the rapid response to antidepressant treatment

Pharmacogenomics Education: International Society of Pharmacogenomics Recommendations for Medical, Pharmaceutical, and Health Schools Deans of Education

Effect of propiverine on cytochrome P450 enzymes: a cocktail interaction study in healthy volunteers

Genetic variants of the insulin receptor substrate-1 are influencing the therapeutic efficacy of oral antidiabetics

CYP2D6 Ultrarapid Metabolism and Morphine/Codeine Ratios in Blood: Was it Codeine or Heroin?

A novel presenilin1 mutation (Q223R) associated with early onset Alzheimer's disease, dysarthria and spastic paraparesis and decreased Abeta levels in CSF

Individualized Medicine - Implementation of Pharmacogenetic Diagnostics in Antidepressant Drug Treatment of Major Depressive Disorders

Assessment of Activity Levels for CYP2D61, CYP2D62, and CYP2D641 Genes by Population Pharmacokinetics of Dextromethorphan

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