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Regulation of muscle protein synthesis and the effects of catabolic states

The international journal of biochemistry & cell biology, 2013-10, Vol.45 (10), p.2147-2157

2013

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Integration of signals generated by nutrients, hormones, and exercise in skeletal muscle

The American journal of clinical nutrition, 2014, Vol.99 (1), p.237S-242S

Kimball, Scot R

2014

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Mechanisms Underlying Muscle Protein Imbalance Induced by Alcohol

Annual review of nutrition, 2018-08, Vol.38 (1), p.197-217

2018

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Signaling pathways and molecular mechanisms through which branched-chain amino acids mediate translational control of protein synthesis

The Journal of nutrition, 2006, Vol.136 (1S), p.227S-231S

2006

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Role of p70S6K1-mediated Phosphorylation of eIF4B and PDCD4 Proteins in the Regulation of Protein Synthesis

The Journal of biological chemistry, 2012-12, Vol.287 (51), p.42890-42899

2012

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ALCAT1 controls mitochondrial etiology of fatty liver diseases, linking defective mitophagy to steatosis

Hepatology (Baltimore, Md.), 2015-02, Vol.61 (2), p.486-496

2015

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REDD1 enhances protein phosphatase 2A-mediated dephosphorylation of Akt to repress mTORC1 signaling

Science signaling, 2014-07, Vol.7 (335), p.ra68

2014

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Evidence for a role for Sestrin1 in mediating leucine-induced activation of mTORC1 in skeletal muscle

American journal of physiology: endocrinology and metabolism, 2019-05, Vol.316 (5), p.E817-E828

2019

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Toll-like receptor activation suppresses ER stress factor CHOP and translation inhibition through activation of eIF2B

Nature cell biology, 2012-02, Vol.14 (2), p.192-200

2012

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Control of Translation Initiation through Integration of Signals Generated by Hormones, Nutrients, and Exercise

The Journal of biological chemistry, 2010-09, Vol.285 (38), p.29027-29032

2010

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ATF4-Mediated Upregulation of REDD1 and Sestrin2 Suppresses mTORC1 Activity during Prolonged Leucine Deprivation

The Journal of nutrition, 2020-05, Vol.150 (5), p.1022-1030

2020

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Exercise Is Medicine for Nonalcoholic Fatty Liver Disease: Exploration of Putative Mechanisms

Nutrients, 2023-05, Vol.15 (11), p.2452

2023

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ATF4 is necessary and sufficient for ER stress-induced upregulation of REDD1 expression

Biochemical and biophysical research communications, 2009-02, Vol.379 (2), p.451-455

2009

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ERK and Akt signaling pathways function through parallel mechanisms to promote mTORC1 signaling

American Journal of Physiology: Cell Physiology, 2011-05, Vol.300 (5), p.C1172-C1180

2011

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Glucagon-Dependent Suppression of mTORC1 is Associated with Upregulation of Hepatic FGF21 mRNA Translation

American journal of physiology: endocrinology and metabolism, 2020-07, Vol.319 (1), p.E26-E33

2020

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New functions for amino acids: effects on gene transcription and translation

The American journal of clinical nutrition, 2006-02, Vol.83 (2), p.500S-507S

2006

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AKT controls protein synthesis and oxidative metabolism via combined mTORC1 and FOXO1 signalling to govern muscle physiology

Journal of cachexia, sarcopenia and muscle, 2022-02, Vol.13 (1), p.495-514

2022

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The mTORC1 signaling repressors REDD1/2 are rapidly induced and activation of p70S6K1 by leucine is defective in skeletal muscle of an immobilized rat hindlimb

American journal of physiology: endocrinology and metabolism, 2013-01, Vol.304 (2), p.E229-E236

2013

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Dexamethasone Represses Signaling through the Mammalian Target of Rapamycin in Muscle Cells by Enhancing Expression of REDD1

The Journal of biological chemistry, 2006-12, Vol.281 (51), p.39128-39134

2006

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Mechanisms Involved in the Coordinate Regulation of mTORC1 by Insulin and Amino Acids

The Journal of biological chemistry, 2011-03, Vol.286 (10), p.8287-8296

2011

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Preventing loss of sirt1 lowers mitochondrial oxidative stress and preserves C2C12 myotube diameter in an in vitro model of cancer cachexia

Physiological reports, 2024-07, Vol.12 (13), p.e16103-n/a

2024

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Emerging role for regulated in development and DNA damage 1 (REDD1) in the regulation of skeletal muscle metabolism

American journal of physiology: endocrinology and metabolism, 2016-07, Vol.311 (1), p.E157-E174

2016

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Interaction between the AMP-activated protein kinase and mTOR signaling pathways

Medicine and science in sports and exercise, 2006-11, Vol.38 (11), p.1958-1964

KIMBALL, Scot R

2006

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Role of precursor mRNA splicing in nutrient-induced alterations in gene expression and metabolism

The Journal of nutrition, 2015-05, Vol.145 (5), p.841-846

2015

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Serum Fibroblast Growth Factor 21 Is Markedly Decreased following Exercise Training in Patients with Biopsy-Proven Nonalcoholic Steatohepatitis

Nutrients, 2023-03, Vol.15 (6), p.1481

2023

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Regulation of muscle protein synthesis and the effects of catabolic states

Integration of signals generated by nutrients, hormones, and exercise in skeletal muscle

Mechanisms Underlying Muscle Protein Imbalance Induced by Alcohol

Signaling pathways and molecular mechanisms through which branched-chain amino acids mediate translational control of protein synthesis

Role of p70S6K1-mediated Phosphorylation of eIF4B and PDCD4 Proteins in the Regulation of Protein Synthesis

ALCAT1 controls mitochondrial etiology of fatty liver diseases, linking defective mitophagy to steatosis

REDD1 enhances protein phosphatase 2A-mediated dephosphorylation of Akt to repress mTORC1 signaling

Evidence for a role for Sestrin1 in mediating leucine-induced activation of mTORC1 in skeletal muscle

Toll-like receptor activation suppresses ER stress factor CHOP and translation inhibition through activation of eIF2B

Control of Translation Initiation through Integration of Signals Generated by Hormones, Nutrients, and Exercise

ATF4-Mediated Upregulation of REDD1 and Sestrin2 Suppresses mTORC1 Activity during Prolonged Leucine Deprivation

Exercise Is Medicine for Nonalcoholic Fatty Liver Disease: Exploration of Putative Mechanisms

ATF4 is necessary and sufficient for ER stress-induced upregulation of REDD1 expression

ERK and Akt signaling pathways function through parallel mechanisms to promote mTORC1 signaling

Glucagon-Dependent Suppression of mTORC1 is Associated with Upregulation of Hepatic FGF21 mRNA Translation

New functions for amino acids: effects on gene transcription and translation

AKT controls protein synthesis and oxidative metabolism via combined mTORC1 and FOXO1 signalling to govern muscle physiology

The mTORC1 signaling repressors REDD1/2 are rapidly induced and activation of p70S6K1 by leucine is defective in skeletal muscle of an immobilized rat hindlimb

Dexamethasone Represses Signaling through the Mammalian Target of Rapamycin in Muscle Cells by Enhancing Expression of REDD1

Mechanisms Involved in the Coordinate Regulation of mTORC1 by Insulin and Amino Acids

Preventing loss of sirt1 lowers mitochondrial oxidative stress and preserves C2C12 myotube diameter in an in vitro model of cancer cachexia

Emerging role for regulated in development and DNA damage 1 (REDD1) in the regulation of skeletal muscle metabolism

Interaction between the AMP-activated protein kinase and mTOR signaling pathways

Role of precursor mRNA splicing in nutrient-induced alterations in gene expression and metabolism

Serum Fibroblast Growth Factor 21 Is Markedly Decreased following Exercise Training in Patients with Biopsy-Proven Nonalcoholic Steatohepatitis

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